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Logo of bmjcrInstructions for authorsCurrent ToCBMJ Case Reports
BMJ Case Rep. 2010; 2010: bcr0420102894.
Published online Nov 26, 2010. doi:  10.1136/bcr.04.2010.2894
PMCID: PMC3027566
Rare disease
Aortic homograft endocarditis caused by Cardiobacterium hominis and complicated by agranulocytosis due to ceftriaxone
Dominique Braun,1 Arthur Horovitz,2 Mihai Bertea,3 Rolf Jenni,4 and Huldrych F Günthard1
1Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland
2Private Practice, Zurich, Switzerland
3Institute of Medical Microbiology, University Hospital Zurich, Zurich, Switzerland
4Department of Cardiology, University Hospital Zurich, Zurich, Switzerland
Correspondence to Dominique Braun, dominique.braun/at/
The present report describes a very rare case of an aortic homograft valve endocarditis caused by Cardiobacterium hominis. The case was complicated by an agranulocytosis after 3 weeks of antibiotic treatment induced by ceftriaxone. Alternative oral treatment with ciprofloxacin and rifampicin was successful, no surgical intervention was needed and homograft function could be preserved.
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