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Logo of bmjcrInstructions for authorsCurrent ToCBMJ Case Reports
BMJ Case Rep. 2010; 2010: bcr0220102777.
Published online Sep 21, 2010. doi:  10.1136/bcr.02.2010.2777
PMCID: PMC3027462
Other full case
Management of tibial non-union with tricalcium phosphate and BMP 7
Jonathan Cubitt1 and Andrew McAndrew2
1Department of Plastic Surgery, Stoke Mandeville Hospital, Aylesbury, UK
2Department of Orthopaedics, Royal Berkshire Hospital Foundation Trust, Reading, UK
Correspondence to Jonathan Cubitt, jonathan.cubitt/at/
We present the case of a 30-year-old woman who was referred with an established tibial non-union with a bone defect following a spiral fracture of the tibia. Initial attempts at union with intramedullary fixation and then autograft were unsuccessful. We achieved union by debriding the fibrous tissue and packing the defect with Bone Morphogenetic Protein 7 (Osigraft, Stryker, UK) and a tricalcium phosphate bone void filler (Calstrux, Stryker, UK). We did not use any additional surgical fixation and the patient was supported in an aircast boot.
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