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BMJ Case Rep. 2010; 2010: bcr0520102970.
Published online Nov 5, 2010. doi:  10.1136/bcr.05.2010.2970
PMCID: PMC3027392
Unusual presentation of more common disease/injury
Solitary fibrous tumour of the lower leg: an uncommon site with atypical histopathological features
Rana K Sherwani and Amit Kumar
Department of Pathology, J N Medical College, AMU, Aligarh, Uttar Pradesh, India
Correspondence to Rana K Sherwani, prof.ranasherwani/at/gmail.com
Abstract
A 40-year-old man of low socioeconomic status presented with a slowly growing painless mass for 1 year at the antero-medial aspect of the right leg. On local examination, the overlying skin was normal and the mass was soft to firm in consistency, non-tender and freely mobile with no fixity to underlying structures. MRI revealed a lobulated mass with central areas of necrosis and no involvement of underlying muscles and neurovascular bundles suggesting a benign soft tissue tumour. The tumour was totally excised and submitted for histopathological examination, which, along with immunopositivity for CD34, CD99 and focally for Bcl2, led to a confirmatory diagnosis of solitary fibrous tumour with atypical histopathological features of increased mitosis and necrosis. After 4 months of follow-up, the patient was disease free without any recurrence or metastasis.
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