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BMJ Case Rep. 2010; 2010: bcr0120102634.
Published online 2010 October 6. doi:  10.1136/bcr.01.2010.2634
PMCID: PMC3027323
Unusual presentation of more common disease/injury

Glycogenic acanthosis presenting as leukoplakia on the tongue


This report describes a rare case of glycogenic acanthosis (GA) located on the tongue of a 72-year-old man. The patient presented with a white plaque that had been on the right side of the tongue for 5 years. Histologically, the lesion was characterised by thickened squamous epithelium with abundant intracellular glycogen deposits. No epithelial dysplasia was noted. This is the first report of GA involving the tongue. This benign condition should be added to the large number of lesions responsible for leukoplakia in this anatomical location.

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