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From:
Published online 2010 December 22. doi: 10.1186/1471-2164-11-724

Figure 1

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Change in computation time and significance threshold for varying region sizes. The change in serial computation time (solid black line) and significance threshold (dotted blue line) are plotted as a function of the mean number of SNPs in each region in a GWAS-wide analysis using the simplex2133 method.