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From:
Published online Dec 2, 2010. doi: 10.1186/1471-2164-11-690
Table 4
Translation initiation factors down regulated in myo1Δ strains.
Initiation Factor/Gene NamesFunction (http://www.yeastgenome.org)Fold Change in Microarray (p≤0.01)Fold Change by Real Time RT-PCR (± s.d.)
eIF1Ad (TIF11)Forms a complex with Sui1p (eIF1) and the 40 S ribosomal subunit and scans for the start codon-2.41-2.52 ± 0.42
eIF2γ (GCD11)Identification of the start codon-1.43-1.26 ± 0.21
eIF2Bβ (GCD7)Guanine-nucleotide exchange factor for eIF2-1.29-1.38 ± 0.27
eIF5 (TIF5)GTPase-activating protein mediates hydrolysis of ribosome-bound GTP-1.25-1.60 ± 0.47
eIF4A (TIF2)RNA helicase-1.32-2.14 ± 0.50
eIF3β (PRT1)Binding of mRNA and Met- tRNAi to ribosomes-1.39-1.87 ± 0.10
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