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Visualization of P-values at the PCSK6 locus. Negative log10 of the P-values for all genotyped and imputed SNPs around PCSK6 plotted in LocusZoom (53). Linkage disequilibrium (r2) with the most highly associated SNP, rs11855415 (purple diamond), is calculated based on the HapMap phase II CEU population and is shown by the colour of the SNPs. The recombination rate is shown by the blue line and the locations of genes in this locus are shown in the panel below the plot.