PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of thijTexas Heart Institute JournalSee also Cardiovascular Diseases Journal in PMCSubscribeSubmissionsTHI Journal Website
 
Tex Heart Inst J. 2010; 37(6): 678–680.
PMCID: PMC3014115

The Case for MinimallyInvasive Surgery inColorectal Cancer and the Development of a Program for Such Surgery

Daniel Albo, MD, PhD
Joseph S. Coselli, MD, Section Editor

Several large, randomized trials have shown that laparoscopic colon and rectal resections are safe, acceptable alternatives to open resections, with additional short-term benefits that include decreased pulmonary and gastrointestinal morbidity, improved pain control, fewer wound complications, and shorter hospital stays.1-4 Despite the accumulating evidence, more than 90% of all colorectal resections for cancer in the United States are still performed through a traditional open approach.5

In the most comprehensive review to date of the utilization patterns of minimally invasive surgery (MIS) in our country, Kemp and Finlayson5 reported that only 6.5% of all colorectal resections are performed by MIS. The proportion of MIS surgeries was only 4.3% for cancer and 8.2% for benign conditions. The utilization rate of MIS in patients with rectal cancer is even worse, with less than 2% of rectal resections performed laparoscopically. These same investigators found that patients treated laparoscopically tended to be younger (median age, 61 vs 66 yr; P <0.001) and tended to have fewer comorbid conditions (Charlson score of zero for 58.1% vs 37%; P <0.001), which runs contrary to logic: the patient group that could benefit the most from MIS (elderly and debilitated patients) was not the group receiving the procedure. Laparoscopic colon resections were more widely adopted in teaching than in nonteaching hospitals (5.1% vs 3.7%; P <0.001) and in urban than in rural hospitals (4.7% vs 2.2%; P <0.001).

The barriers to more widespread adoption of MIS for patients with colorectal cancer (CRC) are not yet fully understood, but they probably include lack of proper training, steep learning curves, and lack of a supportive environment in many hospitals. In order to circumvent these perceived obstacles, we created a minimally invasive CRC program at our institution with the intent of improving the quality of care by increasing the use of MIS in patients with CRC, while maintaining patient safety and oncologic standards.6 A programmatic approach to this problem, we thought, would enable us to rapidly increase the use of MIS and improve clinical outcomes.

Methods

The creation of our MIS program in 2008 involved several components, including

  1. Surgeon retraining, including didactic coursework, animal and cadaver workshops, and preceptorships early in the training curve.
  2. Development of a multidisciplinary colorectal cancer clinic, with embedded clinical pathways and a prospective database.
  3. Development of standardized operative approaches, aided by extensive use of video review.
  4. Strict quality assessment and quality improvement, with weekly morbidity and mortality conferences and multidisciplinary tumor board meetings, peer review, and physician feedback.

Results

Since the inception of our MIS program, we have seen a dramatic increase in our use of MIS in patients with CRC. This increase has been associated with a significant decrease in our rates of conversion from laparoscopic operation to open surgery due to our inability to perform MIS safely or to intraoperative complications (Fig. 1).

figure 18FF1
Fig. 1 Our minimally invasive colorectal surgery program led to the increased use of laparoscopic-assisted surgery and to lower rates of conversion to open surgery in patients with colorectal cancer.

In comparison with patients receiving open surgery, patients receiving laparoscopic resections benefited from much smaller incisions (Fig. 2), lower rates of wound complication, lower reoperative rates, and shorter hospital stays (Table I), without compromising oncologic safety (Table II).

Table thumbnail
TABLE I. Laparoscopic Surgery Offers Significant Short-Term Advantages over Open Surgery in Patients with Colorectal Cancer
Table thumbnail
TABLE II. Oncologic Operative Outcomes Are Similar in Laparoscopic and Open Surgery in Patients with Colorectal Cancer
figure 18FF2
Fig. 2 A) Open surgery versus B) laparoscopic-assisted surgery incisions in low anterior resections for rectal cancer. Laparoscopic-assisted surgery is substantially less invasive than open surgery.

In order to evaluate the impact of our MIS program on our hospital's financial bottom line, we compared the costs of laparoscopic surgery with those of open surgery in our CRC patients. In our experience, the use of MIS led to significant cost savings—both direct and indirect—of almost 50% ($17,047 vs $52,572 for open vs laparoscopic resections; P=0.01) in the surgical man-agement of CRC patients. These decreased treatment costs were largely the consequence of shorter lengths of stay and lower rates of wound complications in the patients who underwent laparoscopic resections. The advantages for hospitals include high surgical volumes (due to increased patient referrals into this type of program) and decreased hospitalization costs, higher revenues, and increased patient satisfaction.

Conclusions

Despite mounting evidence of substantial short-term advantages of MIS over open surgery, MIS remains grossly underused in patients with CRC. Our experience has shown that the development of a program to overcome the impediments to MIS enables a rapid increase in the use of MIS, with substantial benefits to both patients and hospitals.

The advantages for patients and hospitals are outlined above. The advantages for surgeons include higher operative volumes, excellent clinical outcomes, and, most importantly, the chance to do the right thing. Furthermore, the development of a MIS CRC program provides increased educational and research opportunities, enhancing the academic mission and paving the way for exciting new discoveries.

Footnotes

Address for reprints: Daniel Albo, MD, PhD, Division of Surgical Oncology, The Michael E. DeBakey Department of Surgery, Baylor College of Medicine, 1709 Dryden, Suite 1500, Houston, TX 77030

E-mail: ude.mcb@oblad

Presented at the Joint Session of the Denton A. Cooley Cardiovascular Surgical Society and the Michael E. DeBakey International Surgical Society; Austin, Texas, 10–13 June 2010

References

1. Lacy AM, Garcia-Valdecasas JC, Delgado S, Castells A, Taura P, Pique JM, Visa J. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet 2002;359(9325):2224–9. [PubMed]
2. Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AM, et al. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet 2005;365(9472):1718–26. [PubMed]
3. Weeks JC, Nelson H, Gelber S, Sargent D, Schroeder G; Clinical Outcomes of Surgical Therapy (COST) Study Group. Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial. JAMA 2002;287(3):321–8. [PubMed]
4. Colon Cancer Laparoscopic or Open Resection Study Group, Buunen M, Veldkamp R, Hop WC, Kuhry E, Jeekel J, et al. Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol 2009;10(1):44–52. [PubMed]
5. Kemp JA, Finlayson SR. Nationwide trends in laparoscopic colectomy from 2000 to 2004. Surg Endosc 2008;22(5):1181–7. [PubMed]
6. Wilks JA, Balentine CJ, Berger DH, Anaya D, Awad S, Lee L, et al. Establishment of a minimally invasive program at a Veterans' Affairs Medical Center leads to improved care in colorectal cancer patients. Am J Surg 2009;198(5):685–92. [PubMed]

Articles from Texas Heart Institute Journal are provided here courtesy of Texas Heart Institute