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Indian J Psychiatry. 1981 Jul-Sep; 23(3): 251–253.
PMCID: PMC3012953


Sudhir K. Khandelwal, M.D.,2 C. B. Khare, DPM., MD., MNAMS.,1 K. S. Raghavan, Ph.D.,3 and R. Srinivasa Murthy, M.D., MNAMS.4


Two groups of patients on regular lithium therapy were studied to find out the stability in values of serum lithium over a period of time. Serum samples of one group was stored at —4°C while that of other group at room temperature. These samples were subsequently analysed over a period of eight days and subjected to statistical analysis. It was seen that values on the first day did not differ significantly from values of subsequent days. Implications of this findings are discussed in Indian conditions as lithium estimation facilities are available only at a few centres.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Coppen A, Noguera R, Bailey J, Burns BH, Swani MS, Hare EH, Gardner R, Maggs R. Prophylactic lithium in affective disorders. Controlled trial. Lancet. 1971 Aug 7;2(7719):275–279. [PubMed]
  • Prien RF, Caffey EM, Jr, Klett CJ. Prophylactic efficacy of lithium carbonate in manic-depressive illness. Report of the Veterans Administration and National Institute of Mental Health collaborative study group. Arch Gen Psychiatry. 1973 Mar;28(3):337–341. [PubMed]
  • Subhash MN, Narayanan HS, Rao BS, Channabasavanna SM. Monitoring of serum lithium levels in manic depressive psychosis. Indian J Med Res. 1980 Nov;72:712–714. [PubMed]

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