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Annals of the Rheumatic Diseases
 
From:
Published online 2009 May 11. doi: 10.1136/ard.2009.109579

Table 2

Meta-analysis of newly identified rheumatoid arthritis (RA) markers in populations of European ancestry

GWAS meta-analysis11US validation11UK validationMeta-analysis
LocusSNPp ValueORp ValueORp ValueOR (95% CI)p ValueOR (95% CI)Breslow–Day p value
CD40rs48104852.4×10−70.830.0030.912×10−40.86 (0.79 to 0.93)7.8×10−80.87 (0.83 to 0.92)0.31
CCL21rs28123786.9×10−51.139.7×10−41.100.041.08 (1.01 to 1.16)1.2×10−41.09 (1.04 to 1.14)0.81
CDK6rs420415.5×10−51.150.011.080.910.99 (0.92 to 1.08)0.0021.08 (1.03 to 1.14)0.02
GWAS, genome-wide association studies; SNP, single nucleotide polymorphism.