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From:
Published online 2010 December 1. doi: 10.1155/2011/239021

Table 4

Diagnosis of paradoxical TB-IRIS according to consensus case-definition.

Sl. no.TBTB-IRISClinical criteria*
SiteCategoryMajorMinor
(1)DTB (Lung + Pleura + mediastinal LN)ProbableDTB (Lung + Pleura + mediastinal + RP/mesenteric LN)New LNWorsening constitutional symptoms (fever, weight loss, etc.)

(2)LNTB (cervical)DefinitiveDTB (cervical + mediastinal + RP/mesenteric LN)New LNWorsening constitutional symptoms

(3)LNTB (cervical)ProbableDTB (cervical + mediastinal + RP/mesenteric LN)New LNWorsening constitutional symptoms

(4)PTBDefinitivePTBWorsening CXRWorsening constitutional symptoms
Worsening respiratory symptoms (cough, dyspnoea, etc.)

(5)LNTB (cervical)ProbableLNTB (cervical)New & enlarging LNWorsening constitutional symptoms

PTB: pulmonary tuberculosis; RP: retroperitoneal; LN: lymph nodes; DTB: disseminated tuberculosis

*“Antecedent requirements” and “Alternative explanations for clinical deterioration” criteria were fulfilled in all the cases.