Search tips
Search criteria 


Logo of plosonePLoS OneView this ArticleSubmit to PLoSGet E-mail AlertsContact UsPublic Library of Science (PLoS)
Published online 2010 December 13. doi: 10.1371/journal.pone.0014298

Figure 6

An external file that holds a picture, illustration, etc.
Object name is pone.0014298.g006.jpg
HO-1 upregulation leads to less fibrotic and extracellular matrix gene expression as well as TGF-β protein production.

Relative mRNA expression (average ± s.e.m.) of PAI-1 (panel A), collagen types I and III (panels B and C), fibronectin (panel D) and TGF-β (panel E). Samples were obtained from obstructed kidneys of UUO and Hemin-treated groups. Gene expression from control animals was assigned a value of 1. * p<0,05 vs. UUO. (F) TGF-β protein, assessed by ELISA assay, in obstructed kidney samples from UUO and Hemin-treated animals. The amount of TGF-β quantified was divided by total tissue protein. * p<0,05 vs. Control and Hemin.

Images in this article

  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5
  • Figure 6
  • Figure 7
  • Figure 8
  • Figure 9
  • Figure 10
  • Figure 11
  • Figure 12
Click on the image to see a larger version.