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Tissue Antigens
Tissue Antigens. 2010 July; 76(1): 81–85.
PMCID: PMC2996859

Nomenclature for factors of the HLA system, update December 2009

for the WHO Nomenclature Committee for Factors of the HLA System

The following sequences have been submitted to the Nomenclature Committee since the November 2009 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank, Vega or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3.

Table 1
New Sequences
Table 2
Confirmatory Sequences
Table 3
Recently Published Sequences

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the World Wide Web at:


1. Yan LX, Zhu FM, Zhang W, He J. HLA-B*4088, a new allele was identified by polymerase chain reaction sequence-based typing in a Chinese cord blood donor. Tissue Antigens. 2010;75:79–80. [PubMed]
2. Chen MJ, Chu CC, Shyr MH, Lin CL, Lin PY, Yang KL. A novel HLA-B allele, B*5214, detected in a Taiwanese volunteer bone marrow donor using a sequence-based typing method. Int J Immunogenet. 2010;37:39–41. [PubMed]
3. Thude H, Michael M, Loth M, Schorner U, Barz D. Identification of the novel allele, Cw*040110 in a German patient. Tissue Antigens. 2010;75:80–2. [PubMed]
4. Balas A, Garcia-Sanchez F, Vicario JL. The new HLA-Cw*0442 allele possibily generated by a recombination event involving Cw*04010101 and Cw*1801. Tissue Antigens. 2010;75:82–3. [PubMed]
5. Deng ZH, Wang DM, Gao SQ, Xu YP. Characterization of the novel HLA-Cw*0624 allele identified by sequence-based typing. Tissue Antigens. 2010;75:83–4. [PubMed]
6. Endres RO, Redman H, Marcus N. Identification of the HLA-Cw*0774 and DQB1*060105 alleles. Tissue Antigens. 2010;75:84–6. [PubMed]
7. Deng Z, Xu Y, Wang D, Jin S. Description of two novel alleles HLA-Cw*0766 and Cw*0767 identified in a Chinese Han individual by sequence-based typing. Hum Immunol. 2010;71:93–5. [PubMed]
8. Wang DM, Zou HY, Li Z. Identification of a novel HLA-Cw*08 variant allele, Cw*0824. Tissue Antigens. 2010;75:86–7. [PubMed]
9. Chen MJ, Chu CC, Shyr MH, Lin CL, Lin PY, Yang KL. Detection of a rare Caucasoid HLA-DRB1*0337 in a Taiwanese bone marrow donor using sequence-based typing method. Int J Immunogenet. 2010;37:1–3. [PubMed]
10. Parkner A, Mosebach M, Halm-Heinrich I, Heim M. Identification of a novel HLA-DRB1*15 allele, DRB1*1533, in a recently registered stem cell donor. Tissue Antigens. 2010;75:88–9. [PubMed]

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