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Int J Ayurveda Res. 2010 Jul-Sep; 1(3): 196.
PMCID: PMC2996584

More concerns on triphala mouthwash


I read with great interest a recent published work on triphala mouthwash by Tandon et al[1] They concluded that there was no significant difference between triphala and chlorhexidine mouthwashes.[1] I agree that this work confirms the dental usefulness of triphala. The previous report also mentioned the counteraction on biofilm formed on tooth substrate.[2] However, there are some facts on the triphala to be known. Triphala has been recently reported to have an in vitro effect on drug modulating enzymes.[3] Disturbance on cytochrome P450 is mentioned, thereby the likelihood of herb–drug interactions, if these are administered concomitantly, can be expected.[3]


1. Tandon S, Gupta K, Rao S, Malagi KJ. Effect of Triphala mouthwash on the caries status. Int J Ayurveda Res. 2010;1:93–9. [PMC free article] [PubMed]
2. Prabhakar J, Senthilkumar M, Priya MS, Mahalakshmi K, Sehgal PK, Sukumaran VG. Evaluation of antimicrobial efficacy of herbal alternatives (Triphala and green tea polyphenols), MTAD, and 5% sodium hypochlorite against Enterococcus faecalis biofilm formed on tooth substrate: An in vitro study. J Endod. 2010;36:83–6. [PubMed]
3. Ponnusankar S, Pandit S, Babu R, Bandyopadhyay A, Mukherjee PK. Cytochrome P450 inhibitory potential of Triphala: A Rasayana from Ayurveda. J Ethnopharmacol. 2010 [In press] [PubMed]

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