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Saudi J Gastroenterol. 2010 October; 16(4): 307.
PMCID: PMC2995109

Minimum Hepatic Encephalopathy


I read the article ‘Predictors of minimal hepatic encephalopathy in patients with cirrhosis’ by Sharma et al. with interest.[1] The authors have conducted an interesting study, but a few points need to be highlighted. Studies done in the past have also shown the correlation between EEG (electroencephalography) and psychometric hepatic encephalopathy score in up to 73% of the cases and can be used as a non-invasive modality to diagnose cases of minimum hepatic encephalopathy in settings where it is possible.[2]


1. Sharma P, Sharma BC. Predictors of minimal hepatic encephalopathy in patients with cirrhosis. Saudi J Gastroenterol. 2010;16:181–7. [PMC free article] [PubMed]
2. Amodio P, Campagna F, Olianas S, Iannizzi P, Mapelli D, Penzo M, et al. Detection of minimal hepatic encephalopathy: Normalization and optimization of the psychometric hepatic encephalopathy score. A neuropsychological and quantified EEG study. J Hepatol. 2008;49:346–53. [PubMed]

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