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We thank Prof. Wiwanitkit, who has taken keen interest in our article, for his appreciation and constructive comments. He has raised some concerns on the use of this technique in humans: the assessment of the outcome, cell dosage, cost and cost-effectiveness. We have already mentioned that the study was a pilot study that demonstrated the effectiveness of the technique; however, we did not quantify the cell dosage and cost-effectiveness. To address this we are evaluating the cell count/cm2 and the cost-effectiveness of the technique in phase II of the study, the results of which will be communicated on completion of the study.
Competing interests: None declared.