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Indian J Ophthalmol. 2010 Sep-Oct; 58(5): 450–451.
PMCID: PMC2992938

Amyloidosis of lacrimal gland: Authors’ reply

Dear Editor,

We thank Kumar et al[1] for their interest in our article[2] and the comments.

We do agree that cases reported from the series by Leibovitch et al.[3] and Taban et al.[4] were not included, and we also agree that the bilateral case reported by Cheng et al.[5] was not included in the discussion. However, the case described by Knowles et al.[6] was orbital amyloidosis, than mere lacrimal gland involvement.

We would like to clarify that the axial proptosis was 2 mm and 2 mm was the inferior displacement.

We do agree that debulking is essential. However, this patient only had an incisional biopsy for diagnosis and opted to be under follow-up.


1. Kumar V, Goel N, Nicholson L, Shankar J. Amyloidosis of lacrimal gland. Indian J Ophthalmol. 2010;58:348. [PMC free article] [PubMed]
2. Prabhakaran VC, Babu K, Mahadevan A, Murthy SR. Amyloidosis of lacrima gland. Indian J Ophthalmol. 2009;57:461–3. [PMC free article] [PubMed]
3. Leibovitch I, Selva D, Goldberg RA, Sullivan TJ, Saeed P, Davis G, et al. Periocular and orbital amyloidosis: Clinical characteristics, management, and outcome. Ophthalmology. 2006;113:1657–64. [PubMed]
4. Taban M, Piva A, See RF, Sadun AA, Quiros PA. Review: Orbital amyloidosis. Ophthal Plast Reconstr Surg. 2004;20:162–5. [PubMed]
5. Cheng JY, Fong KS, Cheah ES, Choo CT. Lacrimal gland amyloidosis. Ophthal Plast Reconstr Surg. 2006;22:306–8. [PubMed]
6. Knowles DM, 2nd, Jakobiec FA, Rosen M, Howard G. Amyloidosis of the orbit and adnexae. Surv Ophthalmol. 1975;19:367–84. [PubMed]

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