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Pharmacogn Mag. 2010 Oct-Dec; 6(24): 345.
PMCID: PMC2992152

Rapid determination of paeoniflorin


I read the recent publication on rapid determination of paeoniflorin with great interest.[1] Zhou et al. concluded that their new proposed method is a rapid, effective, binary reverse phase rapid resolution liquid chromatographic (LC) method.[1] I have some comments on this work. First, I have a concern on the cost of this new LC method. Is it expensive that prevents it from application in routine usage? Second, the quality management, especially for external quality assessment, is a problem that might prevent the generalization of this new technique.[2] Third, the LC is not the fastest technique for identification. Fluorescence- and electrochemical-based detections might be faster.


1. Zhou X, Chen X, Ge L, Gong H, Tian S, An D. Rapid determination of paeoniflorin from Paeonia sinjiang K. Y. Pan. by rapid resolution liquid chromatography. Phcog Mag. 2010;6:98–101. [PMC free article] [PubMed]
2. Nikolin B, Imamović B, Medanhodzić-Vuk S, Sober M. High performance liquid chromatography in pharmaceutical analyses. Bosn J Basic Med Sci. 2004;4:5–9. [PubMed]

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