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The aim of this work is to validate in greek population the PANDA Questionnaire for the assessment of mild cognitive deficits and dementia in patients with Parkinson's disease.
The study included two groups. The first consisted of 20 patients with Parkinson's disease, who were outpatients in the Movement Disorder Clinic and the Memory Clinic of the Neurological Clinic of two public health general hospitals and a university hospital. The second consisted of 20 healthy controls. The two groups were matched for age and education. Patients with Parkinson's disease were evaluated by an experienced clinical neuropsychologist with Mini Mental State Examination, Clock Test, Instrumental Activities of Daily Living. Healthy controls were evaluated only with Mini Mental State Examination, in order to ensure normal cognitive status. In the two groups, PANDA Questionnaire was also administered.
PD patients performed statistically significantly worse than controls in all PANDA subtests, except the first subtest of immediate recall, where the two groups did not differ. PANDA is very well correlated with all neuropsychological tests. Healthy controls were intact cognitively with all instruments.
Greek version of PANDA can be an effective tool. PANDA has a good correlation with all tests used in this study and differentiates well PD patients from controls. Small sample size is a limitation of the study. In order to complete the validation study, we need a bigger sample.