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Ann Thorac Med. 2010 Oct-Dec; 5(4): 249.
PMCID: PMC2954383

Author’s reply

Sir,

“Wiwanitkit highlighted few notes on the publication” H1N1 infection induced thyroid storm including weather this is the first reported case in litraure and the association between H1N1 infection and the thyroid storm.[1] Infection is frequently quoted as a possible precipitator to thyroid storm. This was highlighted both in the introduction and the discussion of our article. The mechanism by which systemic infections precipitate a storm is not well described in the literature.[28] We are not suggesting that the activation (induction of the storm) occurs because of direct invasion of the virus into the thyroid gland. The word induction surely is not meant to establish that case of correlation.

This case was published in the indexed Annals of Thoracic Medicine on April 14, 2010. Therefore, to our knowledge, we still believe that it is the first case to appear in the English literature that correlates H1N1 with thyroid storm. The case presented by Oguz et al. is quite interesting, however, it was presented in the abstract book of the “European Congress of Endocrinology” that was held between April 24 and 28, 2010, in Czech Republic, that is, after our publication date.

References

1. Bahroon SA. H1N1 infection and thyroid storm. Ann Thorac Med. 2010;5:249. [PMC free article] [PubMed]
2. Jampen C, Müller B, Weiss M. 49-year-old patient with staphylococcal endocarditis and thyrotoxic crisis. Praxis (Bern 1994) 2003;92:1261–4. [PubMed]
3. Balkhy HH. The inevitable! An emergence of a new influenza virus. Ann Thorac Med. 2009;4:109–10. [PMC free article] [PubMed]
4. Yoshie T, Masao Y, Masaya I, Ken S, Hideyuki K. Thyroid crisis caused by respiratory infection, twenty-six years after the onset of Graves’ disease-a case report. J Okayama Saiseikai Gen Hospital. 2004;36:34–8.
5. Petrosillo N, Di Bella S, Drapeau CM, Grilli E. The novel influenza A (H1N1) virus pandemic: An update. Ann Thorac Med. 2009;4:163–72. [PMC free article] [PubMed]
6. Bečejac B, Vrkljan M, Solter M, Sikirica N. Thyrotoxic Crisis in a 75 years old woman. Acta Clin Croat. 2003;42:229–31.
7. Rufener S, Arunachalam V, Ajluni R, Sil A. Thyroid storm precipitated by infection: An atypical case involving multisystem organ dysfunction. Endocrinologist. 2005;15:111–4.
8. Desai B, Shukla A. Thyroid Storm: An Atypical Presentation legionella and parainfluenza Abstracts of Papers Presented At The 154th Research Meeting of The Medical Research Centre of Bombay Hospital Trust on Monday 8th Oct 2007

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