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Fifty subjects with seizure disorder were compared with thirty subjects with bronchial asthma and assessed for depression and suicidal behaviour. 34% of the epilepsy group had a diagnosis of major depressive episode compared to 13.3% of Bronchial Asthma group, which demonstrated a significant difference. Complex partial seizures and use of phenobarbitone had significant association with depression. 16% of the epilepsy group had a history of atleast one suicidal attempt in the previous year with 88% using anticonvulsants. 20% of the group also expressed current suicidal ideation, which correlated with Hamilton Depression Rating Scale total scores.