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Logo of ccforumBioMed CentralBiomed Central Web Sitesearchsubmit a manuscriptregisterthis articleCritical CareJournal Front Page
Crit Care. 2010; 14(Suppl 1): P273.
Published online 2010 March 1. doi:  10.1186/cc8505
PMCID: PMC2934419

Performance of ventilators at simulated altitude: study of fraction of inspired oxygen


We studied the performance of two respirators employing an advanced turbine delivery system: LTV 1000, Tbird VSO2. We assessed the ability of the ventilators to deliver to a normal lung model a set fraction of inspired oxygen (FiO2) at different simulated cabin altitudes.


We used a decompression chamber to mimic the hypobaric environment at a range of simulated cabin altitudes of 1,500, 2,000 and 3,000 meters (4,000, 5,333, 8,000 feet). A model of normal lung was used. Concerning the Tbird VSO2, cabin altitude was input. Ventilators were tested with FiO2 set at 50% and Vt set at 700 ml. We noted the effective FiO2 assessed by the ventilators (paramagnetic analysis). We measured the FiO2 really delivered with a dedicated instrument of the French physiological laboratory of aviation and space medicine of the Air Force. Comparisons of preset and assessed FiO2 to actual measured FiO2 were accomplished using a t test for each altitude.


Figure Figure11 shows the data with FiO2 set at 50%.


On one hand, both ventilators showed a moderate variation between FiO2 set and delivered. On the other hand, variations between FiO2 delivered and assessed are high, suggesting inefficacity of ventilators' paramagnetic analysis in hypobaric conditions.

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