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J Biomol Tech. 2010 September; 21(3 Suppl): S18.
PMCID: PMC2918176

New Directions and Update on MicroRNA Profiling Study



Over the past year, the MARG has focused on 3 biotechnology research and education areas: 1) completion and analysis of aperformance study of multiple DNA microarray and deep-sequencing platforms for microRNA profiling; 2) development of synthetic microRNA standards for validating methods and platforms for microRNA profilingassays in core and research laboratories; and 3) expanding MARG focus to include other genomic profiling platforms.We will present an overview on current MARG activities and new initiatives including the launch of a new webforum for genomic profiling technology and assays. The results of the microRNA profiling study on 5 DNA array platforms and 2 next-generation sequencers will be presented and discussed. Finally, we will summarize our progress in developing a set of synthetic microRNA standards that can be used by core laboratories to test methods and validate platforms for microRNA profiling.These standards will be made available to ABRF member labs after testing in MARG laboratories is complete.

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