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The Protein and Nucleic Acid (PAN) Facility (http://pan.stanford.edu) at Stanford University's Beckman Center is a multifaceted biotechnology fee-for-service laboratory providing services to the Stanford scientific community , other non-profit and biopharmaceutical organizations. The Facility's mission is to be adaptable and responsive to the changing needs of biomedical research by providing basic science investigators continued access to key tools and applications in an efficient and cost effective manner. The Facility offers a diverse array of instrumentation and technical capabilities in Molecular Genetics and Protein Analytics. In Molecular Genetics the services include Gene Expression and Genotypring (Affymetrix microarray), quantitative methylation and mutation analysis (PyroMark), qPCR, DNA sequencing and fragment analysis, Nucleic Acid QC (Agilent Bioanalyzer) and Oligonucleotide synthesis. For protein characterization the laboratory offers Protein Sequencing, Peptide Synthesis, Protein Identification (MALDI), Glycan Profiling (Glycostation) and Biomolecular interaction analysis (Surface Plasmon Resonance – Biacore). Each of our services is staffed and supported by highly experienced and dedicated scientists. Beyond merely making available facilities and services, the PAN facility also enables methods development, and new applications development, designed to meet the needs of the research community requiring the services. We will present research examples where the PAN facility played a significant role in the application of these technologies to basic science projects.