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We appreciate the opinions about our article by Wiwanitkit. The adhesives, mainly ethyl-cyanoacrylate, have been studied by our group in different features.[3,4] Previously, we mentioned that “high temperatures related to exothermic reaction of ethyl-cyanoacrylate polymerization may possibly induce a temporary bactericidal effect” like Dr Viroj Wiwanitkit cited very well in his letter to the editor. Other studies, however, suggest that the antimicrobial activity could be related to the degradation products.[5,6] Formaldehyde, one of degradation products of cyanoacrylate, for example, destroys cell membranes by denaturing the membrane proteins. Toxic degradation products of cyanoacrylate may further slow cell growth, damage its physiological needs, and change its cellular membrane structure by inhibiting a specific receptor.