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Logo of jbcThe Journal of Biological Chemistry
Published online 2010 May 17. doi: 10.1074/jbc.M110.139758


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Trafficking-deficient BK channel mutants are trapped in the ER. a, representative single confocal sections from permeabilized cells co-transfected with the corresponding HA-tagged BK channel site-directed mutant (construct, green) and the endoplasmic reticulum marker expression plasmid pdsRed-ER (ER, red). The merged images are shown in the right-hand panels. b, summary bar graph of Pearson's correlation coefficient for quantitative co-localization of the respective HA-tagged channels with the pdsRed-ER marker (a value of 1.0 would indicate complete co-localization). *, p < 0.05, ANOVA with post hoc Dunnett's test compared with the zero channel.

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