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J Gen Intern Med. 2010 August; 25(8): 847–852.
Published online 2010 May 19. doi:  10.1007/s11606-010-1335-8
PMCID: PMC2896588

Hypertension and Diabetes Prevalence Among U.S. Hispanics by Country of Origin: The National Health Interview Survey 2000-2005

Lina P. Pabon-Nau, MD, MPH,corresponding author1,3 Amy Cohen, BA,2 James B. Meigs, MD, MPH,1 and Richard W. Grant, MD, MPH1



Despite their diverse cultural origins, Hispanics in the US are generally studied as a single ethnic group.


1) Assess demographic and disease-related differences among U.S. Hispanics by country of origin, and 2) Examine the mediating roles of socioeconomic status and acculturation on disease prevalence in these subgroups.

Design and Participants

Using data from the 2000-2005 National Health Interview Survey (NHIS), we compared characteristics of Mexican-Americans with Hispanics originally from: Mexico, Puerto Rico, Central/South America, Cuba, and Dominican Republic (n = 31,240). We stratified the analysis by foreign versus US-born Hispanic subgroups and modeled hypertension and diabetes prevalence, adjusting for demographic and acculturation differences.

Main results

The six Hispanic subgroups were significantly diverse in all measured variables. Prevalence of hypertension (32%) and diabetes (15%) was highest in foreign-born Puerto Ricans. After adjusting for age, BMI, smoking, socioeconomic status and acculturation in foreign-born Hispanics, Puerto Ricans (OR = 1.76 [95% CI: 1.23, 2.50], p = 0.002) and Dominicans (OR = 1.93 [1.24, 3.00], p = 0.004), had higher prevalence of hypertension relative to Mexican-Americans. Adjusted diabetes prevalence among foreign-born Hispanics was half or less in Cubans (OR = 0.42 [0.25, 0.68] p < 0.001), Dominicans (OR = 0.48 [0.26, 0.91], p = 0.02) and Central/South Americans (OR = 0.51 [0.33, 0.78], p = 0.002) relative to Mexican-Americans. Among US-born Hispanic subgroups, Cubans had lower hypertension (OR = 0.53, [0.33, 0.83], p = 0.006) and Mexicans (OR = 0.76 [0.60, 0.98], p = 0.03) had lower diabetes prevalence compared to Mexican-Americans in adjusted models.


The prevalence of hypertension and diabetes varies significantly among Hispanics by country of origin. Health disparities research should include representation from all Hispanic subgroups.

Electronic supplementary material

The online version of this article (doi:10.1007/s11606-010-1335-8) contains supplementary material, which is available to authorized users.

KEY WORDS: diabetes, health status, hypertension, immigrant health, vulnerable populations


There are an estimated 45.5 million Hispanics in the United States, comprising 14% of the US population1. Compared to non-Hispanic whites, this group has been reported to have similar or lower prevalence of hypertension26 and higher prevalence of type 2 diabetes710. In addition, US Hispanics have poorer control of both hypertension and diabetes and greater associated complications such as amputations, end-stage renal disease, and peripheral vascular disease compared to non-Hispanic-whites2,1115.

A large number of epidemiologic studies related to Hispanic health disparities in the US have focused on Mexican-Americans from Southwestern United States28,16,17. Studies evaluating disease prevalence in other Hispanic subgroups have provided conflicting results, partly due to differences in analytical approach and study design. Also, most studies have focused on the historically prominent groups (Mexican-Americans, Puerto Ricans, Cubans), leaving out those of Caribbean, Central, or South American descent1823.

Hispanics, while sharing a common language, are an ethnically and culturally heterogeneous group24. While Mexican-Americans continue to be the largest US sub-group, other nationalities are rapidly growing in size1. In addition to country-of-origin differences, Hispanic individuals may differ in disease risk if they were born in the U.S. or were foreign-born. Therefore, epidemiologic findings derived exclusively from a single Hispanic subgroup may not be generalizable to the overall Hispanic population.

To address these concerns, we used data from the National Health Interview Survey to stratify US Hispanic adults by country of origin and by US- versus foreign-born nativity. To our knowledge, this is the only large-scale national survey which provides information on country of origin for Hispanics. We compared demographic characteristics and calculated the adjusted odds of hypertension and diabetes for each subgroup, to test the hypothesis that data on Mexican–Americans are not representative of other Hispanic subgroups.


Data Source and Participants

The National Health Interview Survey (NHIS) is a yearly face-to-face survey conducted by the National Center for Health Statistics of the Centers for Disease Control and Prevention. NHIS uses a complex sample design involving stratification, clustering, and multistage sampling to allow extrapolation to the US civilian non-institutionalized population. The total response rate for the adults in 2000 to 2005 ranged from 69 to 74%25. Details of the survey design are reported elsewhere 26. In 2000-2005, data were collected for 190,355 adults for the Sample Adult questionnaire, including 32,766 adults (ages 18-85) who answered “yes” to the question “do you consider yourself to be Hispanic or Latino?” NHIS provided the following categories for Hispanic respondents to further self-define ethnicity by their (or their family’s) country of origin: Mexican, Mexican-American, Central/South American, Puerto Rican, Cuban/Cuban American, Dominican, Other Spanish, Multiple Hispanic, and Other Latin American type not specified. For the purposes of our analysis, we excluded subjects who reported “Other Spanish” (1,127), “Multiple Hispanic” (356), or “Other Latin American type not specified”, leaving 31,240 Hispanic adults for our analysis. The survey instrument did not provide respondents with any specific definitions or instructions when choosing country of origin. Although “Mexican” and “Mexican-American” respondents presumably shared a similar Mexican heritage at some level, we found these two groups to be demographically very different and thus we did not combine them in our analyses. Although not part of our main analysis, in a subsidiary analysis we also compared characteristics of all Hispanics to non-Hispanic whites and non-Hispanic blacks (Online Appendix 1 and 2). Self report of diabetes or hypertension was ascertained by the questions: “Have you ever been told by a doctor or other health professional that you had ... hypertension, also called high blood pressure?” and “Other than during pregnancy, have you ever been told by a doctor or health professional that you have diabetes or sugar diabetes?”

Variables Related to Disease Risk, Socioeconomics, and Acculturation

BMI was derived from self-reported weights and heights. Smoking status (never smoked vs. current/past smoker) and education (high school degree/equivalent or greater vs. less than high school) were analyzed as binary variables. US regions were defined as Northeast, Midwest, South, and West based on US census regions. Health insurance (yes or no), employment status (yes or no), and regular place of medical care (yes or no) pertained to the 12 months preceding the interview. We define acculturation as “the process by which individuals adopt the attitudes, values, customs, beliefs and behaviors of a another culture.” This definition has been used elsewhere34. For measures of acculturation, we used the following acculturation proxies: place of birth, years in the US, language of interview, and citizenship status. While place of birth was available for all participants, only foreigners were asked how many years they had lived in the US. We dichotomized years in the US by 10, based on prior research which found that disease prevalence significantly changes after this time period27,28. Patient’s primary language was defined based on whether the interview was conducted in English or Spanish. Other than citizenship (yes or no), no data were collected related to participants’ legal immigration status.

Statistical Methods

Because prior literature suggests that there is a significant relationship between nativity and health status among Hispanics2931, we stratified our analyses by whether subjects were US- or foreign-born. We analyzed participant characteristics using chi-square for categorical variables and t-tests for normally distributed continuous data. We conducted univariate analysis to determine significant predictors of self-reported hypertension and diabetes for all Hispanics. We then created separate multivariate logistic regression models to evaluate the effect of Hispanic country of origin on the odds of hypertension or diabetes relative to Mexican-Americans. We chose Mexican-Americans as our referent group for each analysis because this is the largest Hispanic subgroup in the United States. Models adjusted for variables related to demographics (age, gender, BMI, smoking status, US region of residence), socioeconomic status (high school degree, employed for the past 12 months, insurance status, if receiving routine care), and acculturation (language of interview, years in the US, US citizenship status).

We used a step-wise modeling approach in which we sequentially added significantly independent variables related to demographics, socioeconomics, and acculturation. We used SAS-callable SUDAAN (9.1) for all our analyses. Data were weighted to create nationally representative estimates using sampling weights provided by NHIS32. The Human Studies Committee at the Massachusetts General Hospital approved this research.


Respondent Characteristics by Nativity and Hispanic Sub-group

We found significant demographic differences across Hispanic subgroups that were particularly evident among foreign-born subjects (Table 1). In US-born participants, the greatest differences were in age and BMI. Mexican-Americans were the oldest and had the highest BMI. Insurance status also varied significantly among US-born, with Cubans having the highest rates (85%). Otherwise, all US-born Hispanics reported high rates of high school attainment (70-87%), employment (69-75%) and routine care (76-87%). Fewer than 22% of people in US-born Hispanic subgroups chose to conduct the interview in Spanish.

Table 1
Demographic Characteristics of Hispanic Adults by Subgroups, Ages 18-85 and Stratified by US- vs. Foreign-Born: The National Health Interview Survey 2000-2005a

Among foreign-born US Hispanics, we found significant differences across all variables measured. Dominicans had the highest proportion of females, Cubans were the oldest, and Puerto Ricans had the highest BMI and smoking rates. Foreign-born Mexicans had the lowest rates of high school attainment (32%), insurance (42%), and routine medical care (55%). While more than 60% of all foreign-born had been in the US for over ten years, US citizenship ranged from 20% among Mexicans to 96% for Puerto Ricans. The rates of interviews conducted in Spanish varied from 33% among Puerto Ricans, to 74% among Cubans.

Hypertension Prevalence

Table 2 demonstrates the wide variation in weighted unadjusted prevalence of hypertension across subgroups, with overall rates ranging from 12% for Central/South Americans to 25% for Cubans. Among US-born Hispanics, the unadjusted hypertension rate was highest for Mexican-Americans (20%) and lowest for Dominicans (6%). After adjusting for demographic, socioeconomic and acculturation differences, hypertension rates were similar for all groups except Cubans (OR = 0.53, CI: 0.33, 0.83 vs. Mexican-Americans). Among foreign-born Hispanics, a fully adjusted model showed significantly higher odds of reporting hypertension for Puerto Ricans (OR = 1.76: CI: 1.23, 2.50) and Dominicans (OR: 1.93, CI: 1.24, 3.00).

Table 2
Weighted and Adjusted Estimates of Self-reported Hypertension across Hispanic Subgroups Stratified by US vs. Foreign-Born Adults

Diabetes Prevalence

There was also wide variation in the prevalence of diabetes by Hispanic subgroup and nativity (Table 3). Overall prevalence of diabetes ranged from 4% for Central/South Americans to 11% for Puerto Ricans. For US-born subgroups, diabetes prevalence was lower for Mexicans (OR = 0.76, CI: 0.60, 0.98). In contrast, among foreign-born Hispanics, diabetes prevalence remained significantly lower in fully adjusted models for Cubans (OR = 0.42, CI: 0.25, 0.68), Dominicans (OR = 0.48, CI: 0.26, 0.91) and Central/South Americans (OR = 0.51, CI: 0.33, 0.78, referent group = foreign-born Mexican-Americans).

Table 3
Weighted and Adjusted Estimates of Self-reported Diabetes across Hispanic Subgroups Stratified by US vs. Foreign-Born Adults


We found significant variability in demographic characteristics and disease prevalence by country of origin among US Hispanics. This country of origin effect on hypertension and diabetes prevalence was significant among both US and foreign-born Hispanic immigrants. Us born Cubans had lower hypertension and US born Mexicans had lower rates of diabetes compared to US born Mexican-Americans. Among foreign-born Hispanics, Puerto Ricans and Dominicans had higher hypertension prevalence compared to Mexican-Americans, whereas Cubans, Dominicans and Central/South Americans had lower diabetes prevalence. These results indicate that Hispanics cannot be clustered into one group and that disease prevalence is different among US born versus foreign born subgroups.

Differences in hypertension and diabetes prevalence among foreign-born Hispanics may be explained by several factors. At the individual level, there may be mediators such as interaction with the country of origin’s healthcare system, exercise and dietary habits, and societal and family stressors that may have different degrees of importance based on country of origin. In addition, foreign-born Hispanics may have different patterns of migration/immigration back to their native land33,34. Other examples of social determinants that may influence disease prevalence include demographic and socioeconomic characteristics prior to entering the US and the characteristics of the American community into which an immigrant settles24,34. We found higher prevalence of hypertension in countries with higher prevalence of Hispanic Blacks. Recent studies have shown that prevalence of hypertension was equally high among both Hispanic Blacks and non-Hispanic Blacks.3538. Whether this reflects a true genetic difference among groups or a reflection of unmeasured social determinants needs to be further investigated.

Once foreign-born Hispanics arrive in the US, they undergo a process of acculturation that is likely not uniformly experienced. As people spend more time in the US, they likely adopt American lifestyle habits. Prior research has shown that years in the US is a significant predictor of increasing BMI and poor health outcomes39,40. Conversely, as a positive part of acculturation, they also gain more access to healthcare. The balance between positive and negative aspects of acculturation and how they play out across subgroups has yet to be explored. Although a standard for measuring acculturation has not been reached34,41, our findings indicate that country of origin may be an important proxy for social determinants related to migration and acculturation and must be considered when exploring these processes.

In contrast, the relatively uniform prevalence of hypertension and diabetes among US-born Hispanic subgroups indicates that the determinants of disease expression in these participants are similar across different Hispanic sub-groups. While US-born Hispanics may share common cultural values, our study also indicates that they have high rates of high school education, insurance, and routine care. These factors have been shown to be important determinants of health18,24. We also show that US-born Hispanics lack the language disparity of their foreign-born counterparts.

A strength of this study is the large sample size. Also, this study included Dominicans, and Central/South Americans, which have been excluded in prior Hispanic subgroups analysis. However, our findings must be interpreted in light of certain limitations. First this is a cross-sectional analysis and therefore we cannot attribute causality. Nonetheless it presents a valuable starting point for a future longitudinal analysis of the acculturation process and how it manifests itself in each Hispanic subgroup. Second, the data are self-reported and thus could be biased by under- or over-reporting disease prevalence. However, self-reported hypertension has been shown to be similar to physician-diagnosed hypertension among patients who receive routine care42,43. Another limitation is the issue of misclassification. For instance, although all Puerto Ricans are US-born, because the interviews were conducted only in mainland US, we found that not all Puerto Ricans born outside mainland US considered themselves as US-born. Furthermore, the self-identified Mexican versus Mexican-American categories did not closely correlate with US nativity or years in US. That is, some respondents describing themselves as Mexican were US born whereas other respondents who identified as Mexican-American were born in Mexico. These discrepancies indicate that birthplace alone does not necessarily determine ethnic identity among Mexican and Mexican-American Hispanics. Lastly, although we would have preferred to analyze Central and South Americans as two separate groups, these respondents were grouped into a single category in the NHIS survey.

We conclude that Hispanics are a heterogeneous group and cannot be represented by one subset of this population. This heterogeneity is particularly evident among foreign-born Hispanics. Further, traditional variables of demographics, socioeconomic status, or acculturation do not fully account for differences in disease prevalence across foreign-born Hispanic subgroups. We hypothesize that nationality might be a proxy for risk factors that accompany various migration experiences and the process of acculturation. This concept would be worth exploring in future studies. We need to cease assuming that Mexican Americans or any other Hispanic subgroup are representative of all Hispanics and to take into account the cultural diversity within this population. Future studies should explore how a migrant’s incorporation into the American healthcare system is influenced by the country of origin.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Appendix 1(39K, doc)

Demographic Characteristics of Hispanics in Comparison to Non-Hispanic Whites and Non-Hispanic Blacks* (DOC 38 kb)

Appendix 2(29K, doc)

Estimates of Self-Reported Hypertension and Diabetes for Hispanic Subgroups and Non-Hispanic Blacks compared to Non-Hispanic Whites (DOC 29 kb)


This study was funded by grant number T32HP11001 from the Health Resources and Services Administration of the Department of Health and Human Services to support the Harvard Medical School Fellowship in General Medicine and Primary Care. This study was also funded by Aetna Foundation Inc. to support the Aetna/Disparities Solutions Center Fellowship of Massachusetts General Hospital. The study content is solely the responsibility of the authors and do not necessarily represent the official views of the Department of Health and Human Services.

Conflicts of Interest Dr. Grant was supported by an NIDDK Career Development Award (K23 DK067452). Dr. Meigs was supported by NIDDK K24 DK080140. Dr. Meigs currently has research grants from GlaxoSmithKline and Sanofi-Aventis, and has consulting agreements with GlaxoSmithKline, Sanofi-Aventis, Interleukin Genetics, Kalypsis, and Outcomes Science.


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