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A subscription to Nucleic Acids Research comprises 22 issues. All prices include postage, and for subscribers outside the UK delivery is by Standard Air. Nucleic Acids Research operates a model of continuous online publication, more details of which can be found at www.nar.oxfordjournals.org
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Nucleic Acids Research is published twice monthly by Oxford University Press, Oxford, UK. Annual subscription price is £2009.00/$4018.00/€3014.00. Nucleic Acids Research is distributed by Mercury International, 365 Blair Road, Avenel, NJ 07001, USA. Periodicals postage paid at Rahway, NJ and at additional entry points. Issue Date: July 8, 2010.
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|Cover: The ability to engineer novel enzymes capable of efficiently and specifically modifying DNA sequences is essential for the development of enhanced gene therapies and genetic studies. Recombinase-mediated reassembly of the gene encoding beta-lactamase has enabled the discovery of recombinase variants capable of reacting with sequences present in the human genome. The illustration highlights the amino acid residues evolved for catalysis (shown as spheres) and their position relative to bound substrate DNA (shown as purple and green spheres). Gamma delta resolvase monomers are depicted as orange and blue cartoons. For further information please see the article by C.A.Gersbach et al., Nucleic Acids Res., 2010, 38, 4198–4206).|