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PLoS One. 2010; 5(7): e11424.
Published online 2010 July 2. doi:  10.1371/journal.pone.0011424
PMCID: PMC2896401

Patterning in Birthweight in India: Analysis of Maternal Recall and Health Card Data

Sanja Stanojevic, Editor

Abstract

Background

National data on birthweight from birth certificates or medical records are not available in India. The third Indian National Family Health Survey included data on birthweight of children obtained from health cards and maternal recall. This study aims to describe the population that these data represent and compares the birthweight obtained from health cards with maternal recall data in terms of its socioeconomic patterning and as a risk factor for childhood growth failure.

Methodology/Principal Findings

The analytic sample consisted of children aged 0 to 59 months with birthweight data obtained from health cards (n = 3227) and maternal recall (n = 16787). The difference between the card sample and the maternal recall sample in the distribution across household wealth, parental education, caste, religion, gender, and urban residence was compared using multilevel models. We also assessed the ability of birthweight to predict growth failure in infancy and childhood in the two groups. The survey contains birthweight data from a majority of household wealth categories (>5% in every category for recall), both genders, all age groups, all caste groups, all religion groups, and urban and rural dwellers. However, children from the lowest quintile of household wealth were under-represented (4.73% in card and 8.62% in recall samples). Comparison of data across health cards and maternal recall revealed similar social patterning of low birthweight and ability of birthweight to predict growth failure later in life. Children were less likely to be born with low birthweight if they had mothers with over 12 years of education compared to 1–5 years of education with relative risk (RR) of 0.79 (95% confidence interval [CI]: 0.52, 1.2) in the card sample and 0.70 (95% CI: 0.59, 0.84) in the recall sample. A 100 gram difference in a child's birthweight was associated with a decreased likelihood of underweight in both the card (RR: 0.95; 95% CI: 0.94, 0.96) and recall (RR: 0.96; 95% CI: 0.96, 0.97) samples.

Conclusions

Our results suggest that in the absence of other sources, the data on birthweight in the third Indian National Family Health Survey is valuable for epidemiologic research.

Introduction

Birthweight is a key indicator of the health trajectory of a child. In addition to being an intrinsic endpoint[1], low birthweight is associated with increased risk of numerous adverse health outcomes in childhood[2], and adulthood[3]. Even though India is reported to have one of the highest rates of low birthweight in the world[4], the ideal source of birthweight data in the form of birth certificates or hospital discharge data does not exist in India at the national level. The National Family Health Survey in its third round (NFHS-3), the equivalent of the Demographic and Health Surveys (DHS) in India, obtained information on the birthweight of the children based on maternal recollection as well as by asking mothers to show a health card that records the child birthweight in cases where the delivery was institutional. While there are legitimate concerns related to birthweight data from the DHS, especially the extent of missingness and its representativeness[5], in the sheer absence of any alternative source of birthweight data for research as well as surveillance it is important to investigate the utility of the NFHS-3 data on birthweight. In this study, we investigate the extent and characteristics of the sub-population to which the birthweight data from NFHS-3 can be generalized. Doing so allows researchers to use these data with a clear picture of the population they represent. Since the birthweight data were obtained from two sources in the NFHS-3 (maternal recall and health cards), we sought to determine what populations the data from the two groups represent. We also investigated the extent of similarity in socioeconomic patterning of birthweight in the two groups, and assessed the ability of birthweight from each of these sources to predict subsequent growth failure in childhood.

Methods

Data source

We analyzed data from the third round of the National Family Health Survey of India (NFHS-3) conducted in 2005–06. The NFHS was established to generate representative data at the national and state levels on population and health indicators, with special emphasis on maternal and child health outcomes. The NFHS is the Indian equivalent of the DHS assessments which use standard model questionnaires widely used in more than 80 developing countries[6]. The target population for the 2005–2006 NFHS was children aged 0 to 59 months, women aged 15 to 49 years, and men aged 15 to 54 years[7].

Sampling Plan

Multistage stratified sampling methods were used to create a sample representing individuals from all 29 Indian states[8], [9]. The sample size of each state was proportional to the population and the sample was stratified by urban and rural residence within states. Within state strata, primary sampling units (PSUs) were selected based on probability proportional to population and were villages or clusters of villages in rural areas, and census enumeration blocks within urban areas. Households were randomly selected within PSUs. Within selected households, all women aged 15 to 49 years were eligible to be respondents in the survey. Through a two-phase data collection process, 12 states were surveyed between November 2005 and May 2006, and the remaining 17 states were surveyed between April and August 2006[8]. From 116 652 selected households, 124 385 women participated in the survey out of 131 596 who were eligible, yielding an overall response rate of 94.5%, which ranged between 90% and 99% among all states[9]. Of the 124 385 women who participated in the survey, 36 850 reported having 1 or more live births less than five years before completing the survey. These women reported 51 555 live births within this time frame, and we restricted the sample for this study to singletons alive at the time of survey (n = 48 065). Of this sample, 28 051 children were missing data on birthweight. The sample for the health card analyses comprised of all 3227 children that had their birthweight recorded on a health card, while the sample for the maternal recall analysis comprised of all 16 787 children that had their birthweight recorded based on maternal self-report (Table 1).

Table 1
Weighted frequency of children across household, parent and child covariates by method of birthweight report.

Outcomes

Birthweight was measured in grams (whether from health card or maternal recall) and was used as a continuous variable. We also created a binary indicator of low birthweight based on whether the birthweight was less than 2500 grams or not. We assessed the ability of the birthweight data to predict the child's growth failure as measured by underweight, severe underweight, stunting, severe stunting, wasting and severe wasting. We used data on anthropometry available in the NFHS, which applied the World Health organization (WHO) standards to compute the Z scores for weight-for-age, height-for-age, and weight-for-height. Following WHO guidelines, children with a Z score below two standard deviations for weight-for-age, height-for-age, and weight-for-height were classified as underweight, stunted, and wasted respectively. Children whose Z scores were below three standard deviations were classified as having severe growth failure. Height was measured to the nearest 1 millimeter using a measuring board, taking care to measure length for children less than 2 years of age. Weight was measured using the UNICEF Uniscale to the nearest 100 grams. The data available to us were missing data on anthropometry for 8% of eligible children at the national level because these children were missing data on month and year of birth or had grossly improbable height or weight measurements[9].

Socioeconomic Variables

We used the following variables to compare the socioeconomic patterning of birthweight and low birthweight: household wealth, maternal education, paternal education, caste, residence (urban vs. rural), gender, and religion. Household wealth was operationalized as possession of household assets. The dataset contained an index of 33 household assets and characteristics that had been created using principal components analysis (PCA)[10]. We weighted the PCA scores in the dataset by the household sampling weights to ensure that the distribution was representative of all the households in India and then divided the households into quintiles. Categorical variables for maternal and paternal education were created using data on the number of years of schooling. Maternal education had the following categories: no education (0 years of schooling), primary education (1–5 years), secondary education (6–12 years), and greater than secondary (>12 years of education). The paternal education variable had an additional category for those with greater than 15 years of education.

The caste variable was coded as scheduled caste, scheduled tribe, “other backward class”, general caste, and missing or no caste. This classification (using terminology adopted by the Government of India) focuses more on the socially disadvantaged castes, and all privileged caste groups are represented in the “general” group[11]. Urban residence was categorized as residing in cities, towns or villages. The religion of the head of the household was assigned to each individual, with indicators denoting Hindu, Muslim, Christian, Sikh, and other religions. All analyses were adjusted for the age of the child, maternal age, and birth order.

Analysis

To describe the population that this sample of children with birthweight data represents, we first calculated the frequency distribution of children, by source of birthweight (and for those missing birthweight data), across categories of the covariates (age, gender, household wealth, maternal education, paternal education, caste, and religion). We calculated mean and standard deviation of birthweight and prevalence of low birthweight across the socioeconomic categories in datasets that compared children with data from health cards and maternal recall data. These descriptive analyses used survey analytic methods that account for clustering by primary sampling units and the sampling weights.

We then estimated multivariable regression models with birthweight and low birthweight as two separate outcomes, in order to quantify the adjusted association between the socioeconomic indicators and the outcomes. We additionally estimated models with the anthropometric measures as the outcomes, to evaluate the ability of birthweight and low birthweight in predicting subsequent growth failure in the child. In order to account for the multilevel structure of the data (children nested within households within clusters within states) and to account for clustering, we used a multilevel modeling approach, with random effects specified for households, clusters, and states. We fit linear models for birthweight and generalized linear models with a Poisson distribution and a log link function for low birthweight and anthropometric measures. A Poisson model for binary outcomes is a suitable choice in instances where the outcomes, such as here, are not rare events[12], [13]. For presentation, we report the beta estimates and standard errors for linear models and relative risk (RR) estimates and 95% confidence intervals (CI) for the Poisson models.

In order to compare birthweight data obtained from health cards with data from maternal recall, all multivariable models were fit for two sets of data: a) children with birthweight data from health cards, and b) children with birthweight data as per maternal recall. As an exploratory exercise, we reproduced all analyses in a pooled dataset which included records from the health card and maternal samples.

Ethical Review

The 2005–06 National Family Health Survey was conducted under the scientific and administrative supervision of the International Institute for Population Sciences, (IIPS) Mumbai, India. The IIPS is a regional center for teaching, training and research in population studies, and is associated with the Ministry of Health and Family Welfare, Government of India. The institute conducted an independent ethics review of 2005–06 NFHS protocol. Data collection procedures were also approved by the ORC Macro institutional review board. The study was reviewed by Harvard School of Public Health Institutional Review Board and was considered as exempt from full review as the study was based on an anonymous public use data set with no identifiable information on the survey participants.

Results

Covariate distribution by source of birthweight data

The distribution of children across the social factors between the birthweight data obtained from health cards and maternal recall, while statistically significantly different, did not vary to a great extent (Table 1). The children were mostly from households in the highest wealth quintile (40.32% and 30.66%), with mothers (77.3% and 64.6%) and fathers (81.88% and 73.99%) who had greater than 6 years of education, residing in villages (48.37% and 55.98%) and representing all religion, caste, age and gender groups. Notably, there were no cells with zero frequency in the card and maternal recall datasets. In both datasets, there were more than 8% of children in the 4th wealth quintile, and more than 5% in every category of maternal and paternal education. The only group that had a negligible presence was the lowest wealth quintile. Those missing data on birthweight were mostly children from the lower two quintiles of household wealth (60.5%), living in villages (84.59%), whose mothers did not go to school (64.78%).

Descriptive statistics of birthweight sample

Mean birthweight varied by sociodemographic characteristics in both the datasets (Table 2). The birthweight of children with mothers having over 12 years of formal education (2938 grams, SD: 31.35) and fathers with over 15 years of formal education (2984 grams, SD: 49.71), were substantially higher than those whose parents had no education (2827 grams, SD: 61.18; and 2830 grams, SD: 70.62; respectively) in the card sample. The corresponding figures in the recall sample were 2924 (SD: 17.17) versus 2796 (SD: 20.98) for maternal education and 2956 (SD: 26.86) versus 2780 (SD: 23.64) for paternal education.

Table 2
Mean birthweight (standard deviation) and frequency of low birthweight (LBW) across covariates in the card and recall samples.

There was a gradient in prevalence of low birthweight across categories of household wealth with the lowest prevalence among children from the highest quintile (13.72%; 95% CI: 11.12, 16.31), and the highest prevalence among children from the lowest quintile (19.86%; 95% CI: 11.29, 28.43) in the card sample. Similar patterns were observed in the recall sample. In both card and recall samples the disparities by parental education was similar to that observed with birthweight. Weighted prevalence of low birthweight was lower among boys (16.33%; 95% CI: 13.74, 18.91) compared to girls (19.56%; 95% CI: 16.90, 22.22) in the card sample. The gender differences in prevalence of low birthweight were similar in the recall sample as well. Residents of towns (13.80%; 95% CI: 9.63, 17.97 in the card sample and 17.03%; 95% CI: 14.96, 19.11 in the recall sample) had the lowest prevalence of low birthweight, while rural dwellers had the highest prevalence (19.67%; 95% CI: 16.86, 22.48 in the card sample and 22.15%; 95% CI: 20.80, 23.49 in the recall sample). The differentials across age and caste groups were not substantial.

Social patterning of birthweight and low birthweight

The social patterning of birthweight among children whose mothers reported their birthweight differed from that among children in the health card sample (Table 3). Children from households in the lowest wealth quintile were not substantially different in terms of birthweight from those in the third quintile among those whose mother reported birthweight (β: −16.73; SE: 27.61). Among children whose weight was recorded from a health card, however, those from households in the lowest wealth quintile had substantially higher birthweight than those from the third quintile (β: 198.00; SE: 76.83). Children born to a scheduled tribe family were not different from those born to general caste families among those whose mother reported birthweight (β: 38.61; SE: 24.53). Among children whose weight was recorded from a health card, however, those who were born to a scheduled tribe family had substantially higher birthweight than those born to general caste families (β: 132.50; SE: 47.50).

Table 3
Predicted difference* in birthweight (gm) across categories of covariates by source of data.

There were no discrepancies, however, in the social patterning of low birthweight, whether birthweight data had been recorded from a health card, or obtained by maternal recall (Table 4). In the health card sample, children were less likely to be born with low birthweight if they were from the highest quintile of households compared to the middle quintile (RR: 0.69; 95% CI: 0.51, 0.92) or had mothers with over 12 years of education compared to 1–5 years of education (RR: 0.79; 95% CI: 0.52,1.2). Girls were more likely to be born with low birthweight than boys (RR: 1.17; 95% CI: 0.99, 1.38). Similar social patterning was observed in the maternal recall samples.

Table 4
Relative risk (95% confidence interval) of low birthweight* across covariates by source of data.

Birthweight and childhood growth failure

We observed statistically significant associations between both birthweight (in units of 100 grams) and low birthweight and growth failure later in life (Table 5). A 100 gram difference in a child's birthweight in the card sample was associated with decreased likelihood of stunting (RR: 0.97; 95% CI: 0.96, 0.98), underweight (RR: 0.95; 95% CI: 0.94, 0.96), and wasting (RR: 0.96; 95% CI: 0.94, 0.97) at an older age in the card sample. The corresponding figures in the recall sample were 0.98 (95% CI: 0.97, 0.98), 0.96 (95% CI: 0.96, 0.97), and 0.97 (95% CI: 0.96, 0.97) in the recall sample. In the card sample, low birthweight was associated with increased likelihood of stunting (RR: 1.41; 95% CI: 1.18, 1.67), underweight (RR: 1.77; 95% CI: 1.48, 2.12), and wasting (RR: 1.67; 95% CI: 1.32, 2.11) in later life. A similar pattern was seen in the recall sample for stunting (RR: 1.32; 95% CI: 1.24, 1.41), underweight (RR: 1.57; 95% CI: 1.46, 1.68) and wasting (RR: 1.41; 95% CI: 1.28, 1.55).

Table 5
Relative risk (95% CI) for the association between growth failure* and birthweight/low birthweight by source of data.

The mean birthweight and proportion of low birthweight across covariates (Table S1), socioeconomic patterning of low birthweight (Table S3) and the association between birthweight and growth failure at a later age (Table S4) in the pooled sample were similar to the results in both the card and recall samples. The socioeconomic disparities in birthweight (Table S2) were closer to the results from the recall sample but not the card sample.

Discussion

This study has two key findings. First, we found that contrary to prevalent beliefs [5], [14] the Indian National Family Health Survey-3 contains birthweight data from a majority of household wealth categories, both genders, all age groups, all caste groups, all religion groups and urban and rural dwellers. Second, our comparison of low birthweight data across two sources—health card records and maternal recall—revealed that the data were similar with regards to their socioeconomic patterning, and especially in predicting growth failure in childhood using low birthweight.

While there are multiple studies of birthweight in India[15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], some of them well designed community-based cohorts[30], [31], [32], [33], they remain local studies. The NFHS-3 is the only source that provides data from a sample of individuals across the country and includes data from a majority of sociodemographic groups of the Indian population. The households in the poorest wealth quintile, however, were much underrepresented. We found that there was some representation of every level of the sociodemographic factors we examined in both of the sources of birth weight data: the health cards and maternal recall. However, the proportion of missingness was not the same across these social factors. As might be expected, there was relatively greater missing data among the poorest, least educated, those belonging to disadvantaged caste groups, and rural dwellers. Despite this social patterning in missingness, these findings highlight the sub-population of India to whom analyses of birthweight are generalizable: children across India, of both genders, aged less than five years, of all caste and religion groups, and belonging to middle and wealthier households. Arguably this encompasses a large proportion of the population of children under age five in India.

Although we posit that these data represent a specific subgroup of children within the Indian context, it may be possible to extrapolate these data to the larger population. For example, researchers interested in using these data might be able to come up with weighting schemes to account for the social patterning in missingness. Such weighting techniques have already been proposed to account for the heaping of birthweight recall data at multiples of 500 grams in order to estimate the prevalence of low birthweight at the country level[5].

Our comparison of birthweight from two sources of the data in the survey, health cards and maternal recall, revealed that the differences between the two might not be as large as has previously been discussed, especially for low birthweight[5]. This method of comparison, wherein the measures of birthweight in two groups are compared on their associations with other variables, with prior knowledge as to what these associations look like, is called “criterion related validation”[34]. Specifically, we found, in both groups, socioeconomic advantages to be associated with lower likelihood of low birthweight, consistent with previous studies[19], [21], [31]. We also found associations of birthweight and low birthweight with later growth failure that were consistent with those of earlier research in both groups[35]. These results are generalizable only to the sub-population described previously.

To our knowledge only one published study has evaluated birthweight data from the Indian NFHS[5]. This study used data pooled from 62 countries including Indian data from 1992 and 1999, but not from 2005–2006. Since we use only 2005–2006 Indian data, our study is not strictly comparable with the Blanc and Wardlaw study. While Blanc and Wardlaw address heaping in actual birthweight data, they mostly focus on an assessment of “baby size” by mothers (“larger than average”, “smaller than average”, etc). This variable provides important information that can supplement the use of actual birthweight. Dharmalingam and colleagues have suggested that this is a useful proxy for birthweight[14], citing the findings by Blanc and Wardlaw as evidence to support their use of this variable. However Blanc and Wardlaw found that, while consistent at the aggregate level, the correlation between baby size and birthweight was variable at the individual level. We posit that ignoring the data on actual birthweight in the NFHS is to ignore valuable data. Information on baby size can potentially be used in conjunction with data on birthweight to provide a more comprehensive picture.

Our results must be interpreted keeping in mind several limitations regarding the quality of the data. One assumption we have made is that birthweight data taken from the health card are reliable. Specifically, these cards are filled out by medical professionals at health care institutions while attending the birth of the child. Since these cards are typically filled out at the same time as a standard medical record by the same individual, there is little reason to think that the quality of the data from these cards would vary widely from that of other medical records, which are taken as a gold standard for medical information retrieval. Another possible limitation is that mothers in India may recall birthweight differently for malnourished children compared to those who are not malnourished. The fact that we found birthweight reported by maternal recall to have similar patterns compared with objectively measured birthweight from the health cards provides evidence that this limitation cannot completely account for our results. As the data on all children of one mother were collected at one time point, there is a chance that mothers providing data on more than one child might report similar or even identical birthweight for all their children. However, our modeling techniques account for clustering of data and moreover, we found that our findings were robust even when we dropped the records of siblings with identical birthweight. Most importantly, the purpose of our analysis is to encourage the efficient use of existing rich data. However, the extent of missing data, especially among the disadvantaged sections of the Indian population, cannot be addressed by modeling or weighting techniques. A conscientious attempt at gathering data from all socioeconomic groups would allow researchers and policy-makers to work towards prevention of low birthweight as well as reduction of social disparities in child health.

Conclusion

Birthweight is a key variable for measuring the quality of the prenatal medical and social environment as well as predicting future individual health outcomes. Our study describes the population to which results of studies using existing birthweight data might be generalized, which is valuable in the Indian context where ensuring completion of data in a national survey is a daunting challenge, especially given the high proportion of home births. These birthweight data appear especially suitable for studies focused on examining the effect of low birthweight on other social and health outcomes. This study indicates that birthweight data from health cards and maternal recall data from the 2005–2006 NFHS can be used to study the epidemiology of low birthweight in India with appropriate cautions.

Supporting Information

Table S1

Mean birthweight (standard deviation) and frequency of lowbirthweight (LBW) across covariates in the pooled sample (card + recall).

(0.08 MB DOC)

Table S2

Predicted difference* in birthweight (gm) across categories of covariates in the pooled sample (card + recall). Footnote: Models additionally adjusted for age, maternal age, and birth order.

(0.06 MB DOC)

Table S3

Relative risk (95% confidence interval) of low birthweight* across covariates in the pooled sample (card + recall). Footnote: *Models additionally adjusted for age, maternal age and birth order, and conditional on random effects.

(0.06 MB DOC)

Table S4

Relative risk (95% CI) for the association between growth failure* and birthweight/low birthweight in the pooled sample (card + recall). Footnote: Birthweight and low birthweight were included in separate models. The RRs for birthweight are for 100 gm difference. All models additionally adjusted for household wealth, caste, religion, urban residence, maternal and paternal education, age, gender, maternal age, and birth order and are conditional on random effects.

(0.05 MB DOC)

Acknowledgments

We acknowledge the support of Macro International Inc. (Washington, DC) for providing access to the NFHS-3 data.

Footnotes

Competing Interests: The authors have declared that no competing interests exist.

Funding: No direct funding was available for this study. SVS is supported by a National Institutes of Health Career Development Award (NHLBI K25 HL081275). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

References

1. Wilcox AJ. Response: Where do we go from here? International Journal of Epidemiology. 2001;30:1245–1245.
2. Wilcox AJ. On the importance—and the unimportance—of birthweight. Int J Epidemiol. 2001;30:1233–1241. [PubMed]
3. Whincup PH, Kaye SJ, Owen CG, Huxley R, Cook DG, et al. Birth weight and risk of type 2 diabetes: a systematic review. JAMA. 2008;300:2886–2897. [PubMed]
4. WHO. New York: UNICEF; 2004. Low birth weight: Country, regional and global estimates.
5. Blanc AK, Wardlaw T. Monitoring low birth weight: an evaluation of international estimates and an updated estimation procedure. Bull World Health Organ. 2005;83:178–185. [PubMed]
6. DHS. Calverton, MD: MEASURE DHS; 2009. Demographic and Health Surveys.
7. IIPS, ORC-Macro. Mumbai: International Institute for Population Sciences; 2007. National Family Health Survey, 2005-2006: India.
8. IIPS, Macro-International. Mumbai: International Institute for Population Sciences; 2007. National Family Health Survey (NFHS-3), 2005-2006: India: Volume I.
9. IIPS, Macro-International. Mumbai: International Institute for Population Sciences; 2007. National Family Health Survey (NFHS-3), 2005-2006: India: Volume II.
10. Filmer D, Pritchett LH. Estimating wealth effects without expenditure data—or tears; an application to educational enrollments in states of India. Demography. 2001;38:115–132. [PubMed]
11. Chitnis S. Definition of the terms scheduled castes and scheduled tribes: a crisis of ambivalence. In: PaiPanandiker VA, editor. The Politics of Backwardness : Reservation Policy in India/edited by VA Pai Panandiker. New Delhi: Konark; 1997. pp. 88–107.
12. Zou G. A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol. 2004;159:702–706. [PubMed]
13. Barros AJ, Hirakata VN. Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. BMC Med Res Methodol. 2003;3:21. [PMC free article] [PubMed]
14. Dharmalingam A, Navaneetham K, Krishnakumar CS. Nutritional Status of Mothers and Low Birth Weight in India. Matern Child Health J 2009 [PubMed]
15. Sarkar NC, Saikia AC. Birth weight at Changlang, Arunachal Pradesh. Indian J Pediatr. 2000;67:419–421. [PubMed]
16. Mathai M, Vijayasri R, Babu S, Jeyaseelan L. Passive maternal smoking and birthweight in a south Indian population. Br J Obstet Gynaecol. 1992;99:342–343. [PubMed]
17. Prasad KN, Rao RS, Sujatha A. Birth weight pattern in Karnataka. Indian Pediatr. 1994;31:836–839. [PubMed]
18. Antonisamy B, Rao PS, Sivaram M. Changing scenario of birthweight in south India. Indian Pediatr. 1994;31:931–937. [PubMed]
19. Misra M, Mishra S, Sharadamma Epidemiology of low birth weight in an industrial area in India. J Trop Pediatr. 1995;41:374–376. [PubMed]
20. Deshmukh JS, Motghare DD, Zodpey SP, Wadhva SK. Low birth weight and associated maternal factors in an urban area. Indian Pediatr. 1998;35:33–36. [PubMed]
21. Nair NS, Rao RS, Chandrashekar S, Acharya D, Bhat HV. Socio-demographic and maternal determinants of low birth weight: a multivariate approach. Indian J Pediatr. 2000;67:9–14. [PubMed]
22. Muthayya S, Kurpad AV, Duggan CP, Bosch RJ, Dwarkanath P, et al. Low maternal vitamin B12 status is associated with intrauterine growth retardation in urban South Indians. Eur J Clin Nutr. 2006;60:791–801. [PubMed]
23. Patel V, Prince M. Maternal psychological morbidity and low birth weight in India. Br J Psychiatry. 2006;188:284–285. [PubMed]
24. Kulkarni B, Shatrugna V, Balakrishna N. Maternal lean body mass may be the major determinant of birth weight: A study from India. Eur J Clin Nutr. 2006;60:1341–1344. [PubMed]
25. Muthayya S, Dwarkanath P, Thomas T, Vaz M, Mhaskar A, et al. Anthropometry and body composition of south Indian babies at birth. Public Health Nutr. 2006;9:896–903. [PubMed]
26. Bisai S, Mahalanabis D, Sen A, Bose K, Datta N. Maternal early second trimester pregnancy weight in relation to birth outcome among Bengalee Hindus of Kolkata, India. Ann Hum Biol. 2007;34:91–101. [PubMed]
27. Dwarkanath P, Muthayya S, Vaz M, Thomas T, Mhaskar A, et al. The relationship between maternal physical activity during pregnancy and birth weight. Asia Pac J Clin Nutr. 2007;16:704–710. [PubMed]
28. Kanade AN, Rao S, Kelkar RS, Gupte S. Maternal nutrition and birth size among urban affluent and rural women in India. J Am Coll Nutr. 2008;27:137–145. [PubMed]
29. George K, Prasad J, Singh D, Minz S, Albert DS, et al. Perinatal outcomes in a South Asian setting with high rates of low birth weight. BMC Pregnancy Childbirth. 2009;9:5. [PMC free article] [PubMed]
30. Rao S, Kanade AN, Yajnik CS, Fall CH. Seasonality in maternal intake and activity influence offspring's birth size among rural Indian mothers—Pune Maternal Nutrition Study. Int J Epidemiol. 2009;38:1094–1103. [PMC free article] [PubMed]
31. Hirve SS, Ganatra BR. Determinants of low birth weight: a community based prospective cohort study. Indian Pediatr. 1994;31:1221–1225. [PubMed]
32. Gupta PC, Sreevidya S. Smokeless tobacco use, birth weight, and gestational age: population based, prospective cohort study of 1217 women in Mumbai, India. BMJ. 2004;328:1538. [PMC free article] [PubMed]
33. Agnihotri B, Antonisamy B, Priya G, Fall CH, Raghupathy P. Trends in human birth weight across two successive generations. Indian J Pediatr. 2008;75:111–117. [PMC free article] [PubMed]
34. Carmines EG, Zeller RA. Thousand Oaks, CA: Sage; 1979. Reliability and validity assessment.
35. Rehman AM, Gladstone BP, Verghese VP, Muliyil J, Jaffar S, et al. Chronic growth faltering amongst a birth cohort of Indian children begins prior to weaning and is highly prevalent at three years of age. Nutr J. 2009;8:44. [PMC free article] [PubMed]

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