Both reciprocal and non-reciprocal exchanges are found in DNA damage–induced TYR1 recombinants.
(A) Minimal estimation of reciprocal exchanges (RE) was obtained by PCR amplification of TYR1
locus of Tyr+
colonies (details in text and in ) (The numbers of events were “y
” was identified or not are presented). (B) Calculation of excepted frequency of RE in TYR1
locus of irradiated cells. The minimal estimate for RE frequency among Tyr+
recombinants (7A) was multiplied by 2, assuming that all events occurred in G2
) and then was multiplied by the frequency of Tyr+
induced recombinants as measured in .
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