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To determine the prevalence of self-reported napping and its association with subjective nighttime sleep duration and quality, as measured by sleep-onset latency and sleep efficiency.
Lifestyle Interventions and Independence for Elder’s Pilot Study.
Community-dwelling older adults (N=414), aged 70 to 89 years.
Self-report questionnaire on napping and sleep, derived from the Pittsburgh Sleep Quality Index (PSQI) scale.
A total of 54 percent of participants reported napping with mean nap duration of 55 minutes, (SD 41.2 minutes). Compared to non-nappers, nappers were more often men (37.3% vs. 23.8%, P = .003), African American (20.4% vs.14.4%, P = .06), or diabetic (28% vs. 14.3%, P = .007). Nappers and non-nappers had similar nighttime sleep duration and quality, but nappers spent about 10 percent of their 24-hour sleep occupied in napping. In a multivariate model, the odds of napping were higher for diabetics (OR: 1.9; 95% CI: 1.2–3.0) and men (OR: 1.9; 95% CI: 1.2–3.0)). In nappers, diabetes mellitus (β = 12.3 minutes, P =.005), male gender (β = 9.0 minutes, P = .04), higher BMI (β = 0.8 minutes, P = .02), and lower MMSE (β = 2.2, P = .03) were independently associated with longer nap duration.
Napping was a common practice in community-dwelling older adults and did not detract from nighttime sleep duration or quality. Given its high prevalence and association with diabetes, napping behavior should be assessed as part of sleep behavior, both in future research and in clinical practice.
A significant proportion of older adults report napping, with prevalence estimates ranging from 23 to 61 percent.1,2 Napping has generally been discussed in terms of its negative impact on sleep hygiene, particularly through increased sleep-onset latency,3,4 increased nighttime awakenings,5,6 and decreased nighttime sleep.7,8 Given the older adult’s increased risk of disrupted sleep quality and increased occurrence of fragmented sleep, any practice that may worsen nighttime sleep should be avoided. However, there is a gap in knowledge as to what specific effect napping has on nocturnal sleep and if it is a marker of poor health.
Poor nighttime sleep and daytime sleepiness, which may be associated with napping9,10 have detrimental impacts on mood, attention, memory, and quality of life, along with public health concerns of increased fall risk, usage of sedating medications, and mortality in the older adult.11,12,13,14,15 The time a nap occurs during the day, specifically an evening nap, may lead to disrupted sleep in older adults, especially decreased nocturnal sleep, which may be explained by altering their circadian rhythms.8,16 Large epidemiological studies of older adults have found napping to be an independent risk factor for mortality, especially on cardiovascular health. More recent data show that heart rate and blood pressure significantly increase after awakenings, both after nocturnal and daytime sleep.17,18,19,20,21,22 Still others report that napping improves mood and cognitive performance, having little or no impact on nighttime sleep.1,23,24,25,26 Few even report that napping may decrease coronary heart disease risk, depending on nap duration and health status.27,28 Despite the growing literature on napping, few studies to date specifically address the prevalence of napping in sedentary community dwelling adults, who are not selected by specific sleep complaints.8,29 Furthermore, few studies have described the correlation of napping to co-morbidity.
Our objective was to characterize the prevalence of self-reported napping in a group of community dwelling older adults with impaired physical performance and determine its association with nighttime sleep duration, sleep-onset latency, and sleep efficiency. We also sought to identify if other demographic factors, performance variables, and co-morbid conditions were predictive of napping using standardized, interview administered questionnaires in these community-dwelling older adults. We hypothesized that self-reported napping was related to fewer hours of reported nighttime sleep, longer sleep-onset latency, and decreased sleep efficiency, along with a greater prevalence of co-morbid psychological and physical illnesses in nappers.
Data were collected on participants enrolled in the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) study. 30,31 LIFE-P is a multi-center, single-blind, randomized controlled clinical trial in which community-living sedentary older adults age 70 to 89 at risk for disability were assigned to either physical activity or “successful aging” intervention lasting between 12 and 18 months depending on the month of randomization. The physical activity intervention consisted of a structured exercise program focused on walking supplemented with behavioral counseling. The “successful aging” intervention consisted of educational meetings not expected to impact the main study outcomes. Participants were recruited primarily via direct mailings, but media advertisements (radio and newspaper advertisements, press releases, articles) and other community outreach efforts were also used. The goal of the LIFE-P study was to obtain key design benchmarks in preparation for a larger study of the efficacy of physical activity for preventing disability in this population. The study was approved by the local institutional review boards of all four participating field centers (The Cooper Institute, Dallas, TX; Stanford University, Stanford, CA; University of Pittsburgh, Pittsburgh, PA; and Wake Forest University, Winston-Salem, North Carolina) and all enrolled participants gave written informed consent. The protocol is consistent with the principles of the Declaration of Helsinki and is registered at www.ClinicalTrials.gov (registration # NCT00116194).
The design and methods of the trial are described in detail elsewhere. 30,31 Briefly, eligibility criteria included being able to walk 400 meters within 15 minutes without sitting and without the use of any assistive device, having a Short Physical Performance Battery (SPPB) score of ≤9 [The SPPB is a standardized, well documented measure of lower extremity physical performance that includes walking, balance, and strength tasks, scaled 0–12, higher scores indicating better performance32], having completed a behavioral run-in related to logging health behavior, given informed consent, living in the study area, and not planning to move for at least nine months. Participants were ineligible if they had severe heart failure, uncontrolled angina, severe pulmonary disease, chest pain or severe shortness of breath during the 400-meter walk test, severe arthritis, cancer requiring treatment in the past three years, Parkinson’s disease, other severe illness that may interfere with physical activity, illness with life expectancy of less than 12 months, or a Mini-Mental State Examination (MMSE) score < 21. Temporary exclusion criteria were acute myocardial infarction, deep venous thrombosis, pulmonary embolism, major arrhythmias, stroke within six months, recent major surgery, uncontrolled hypertension, uncontrolled diabetes mellitus, or ongoing lower extremity physical therapy.
Baseline cross-sectional data on nap duration and prevalence, nighttime sleep duration, sleep-onset latency, and efficiency were collected via standardized interview at baseline. Of the 424 participants, 414 had completed data on napping and sleep and are included in the analysis.
Napping and sleep were assessed using a standardized interview. Participants were asked “During the past month, how many hours do you nap or sleep during a typical day?” Those reporting > 0 minutes of napping were classified as nappers. The Pittsburgh Sleep Quality Index (PSQI) items 1–433 were used to assess the following sleep measures: total time in bed, nighttime sleep duration, sleep-onset latency, and sleep efficiency.
Demographics variables assessed at baseline included age, sex, and self-designated race, marital status, level of education and self-report of smoking. Chronic health conditions considered as potential confounders included the following: hypertension, diabetes mellitus, cancer, myocardial infarction, congestive heart failure, stroke, or pacemaker placement, were assessed by self-report. Weight was assessed by a calibrated scale and height by stadiometer. Body mass index (BMI) (kg/m2) was calculated. Cognition, mood, fatigue, and pain were also considered as potential confounders. Cognitive function was assessed with the Folstein Mini-Mental State Examination (MMSE), depression symptoms with the Center for Epidemiologic Studies Depression (CES-D) Scale,34 energy level with a 6-item fatigue and energy questionnaire from the Modified Exercise-Induced Feeling Inventory, and pain symptoms with a modified 12-item pain scale and a pain frequency scale.
Wilcoxon-Mann-Whitney t-tests and chi-square analyses were used to examine differences between means and categorical variables between nappers and non-nappers. Logistic regression was used to examine the odds of taking a daytime nap (odds ratio 95% confidence interval). Stepwise linear regression was conducted to assess predictors of nap duration (minutes), as a continuous outcome. All models were adjusted for variables associated with napping in either univariate analysis or previous literature report.11,15 Variables that did not reach a significance of ≤.10 were excluded from the final models.
Descriptive characteristics of the 414 participants are shown in Table 1, and are stratified by napping status. Napping was reported by 54 percent of participants. Average nap duration for nappers was 55 minutes (SD 41.2 min). Men reported napping more than women, and napping was more prevalent in African-Americans compared with Caucasians and other racial/ethnic minorities, but did not reach statistical significance. There was no difference in average age with respect to napping status.
Diabetes mellitus was more prevalent among those who reported napping (Table 1). Nappers had lower energy/fatigue scores than non-nappers, indicating less energy. There was a marginal, but non significant difference in terms of both a higher BMI and higher CES-D score, indicating more depression symptoms, in nappers versus non-nappers. There was no difference in the prevalence of cardiovascular diseases between nappers and non-nappers (Table 1).
Contrary to our hypothesis, there was no difference between any nighttime sleep parameters in terms of average reported nighttime sleep duration, sleep-onset latency, or sleep efficiency, between nappers and non-nappers (Table 2). While there was no difference in reported nighttime sleep duration between nappers and non-nappers, when accounting for total 24 hour sleep, nappers had greater total sleep duration compared to non-nappers, with about 10 percent of their total sleep occupied in napping (Table 2).
In the logistic regression model (Table 3), the unadjusted odds ratio for nappers was higher in men and diabetics. In the fully adjusted model, men and diabetics had significantly higher odds of napping, which were not attenuated by adjustment of other factors (Table 3).
Among nappers, male gender, diabetes mellitus, and higher BMI were all associated with longer nap duration in the unadjusted linear regression model, which continued to hold the same associations in the fully adjusted model (Table 4). In the fully adjusted model, lower MMSE scores also became associated with longer nap duration. Male gender was associated with nine minute longer nap duration, while diabetes was associated with 12 minute longer nap duration. In both the logistic and linear models, none of the nighttime sleep parameters were associated with napping status or duration.
Self-reported napping was quite common in this group of sedentary, community-dwelling older adults with impaired physical performance. The finding that 54 percent of older adults napped at least once a week is within the range that others have reported.8,26,35,36 Currently, not all sleep studies routinely ask about nap behaviors. This study adds further supporting evidence that the prevalence of napping in older adults is high, and clearly must be accounted for in sleep studies involving older adults.
This study failed to show a clear association between age and napping, unlike others who have shown that the prevalence of napping increases with age.1,26,29,37 This difference could be explained by the fact that our population had a more narrow range of ages, focusing on the “oldest” old (70–89 years), while others have compared napping behavior between “younger” old (50–60 years) and “oldest” old (70–80 years). Men napped significantly more than women, which has been noted by others.1,26,38,39,40 While few studies have looked specifically at napping and race, our results suggest that African Americans nap more than other racial groups, a finding reported in two other studies.41,42
Reported poor sleep was not more prevalent in nappers versus non-nappers. There was no difference between nappers and non-nappers in terms of reported nighttime sleep duration, sleep-onset latency, or sleep efficiency. This finding is consistent with others,7,29 one of which used objective measures to show that daytime sleep was not related to nocturnal sleep in post-menopausal women. While self-reported napping did not have a negative effect on reported nighttime sleep as we had hypothesized, there is a speculation that napping may actually be a compensation for daytime sleepiness incurred from fragmented nighttime sleep. Sleep apnea43 or sleep fragmentation due to nocturia10,44,45 are two prevalent conditions that may not be reported as detracting from nocturnal sleep duration and quality but may still contribute to daytime sleepiness and thus increase the propensity to nap. A recent population based study suggested that napping could be regarded as a marker of sleep apnea, which could account for the incidence of cardiovascular diseases observed in nappers. Data in that study showed that nappers had a higher frequency of sleep apnea compared to controls at three different cutoff points.46 In addition, a study of female insomniacs showed that habitual nap behavior was not related to subjective or objective measures of nocturnal sleep but was rather indicative of their daytime sleepiness.47 This may be suggested by our finding that nappers spent 10 percent of 24-hour sleep occupied in napping, despite having no significant difference in nocturnal sleep parameters as compared to non-nappers.
In this cohort, napping was more prevalent in those with diabetes mellitus. The diagnosis of diabetes mellitus and higher BMI were also associated with longer nap duration. This finding provides a new piece of evidence that diabetes mellitus has an effect on daytime sleep. Others have described poor nighttime sleep in diabetics, particularly with respect to altered sleep durations48 and sleep disordered breathing,49,50 along with higher rates of insomnia, hypnotic medication use, and daytime sleepiness compared to controls. Studies correlating diabetes mellitus with increased daytime sleepiness have shown that daytime sleepiness was greatest in those with frequent nocturnal micturition episodes, somewhat explained by increased sleep apnea syndrome. Further study with objective actigraphy or polysomnography measurements of nighttime sleep and napping behavior is required to address such hypotheses.
A limitation to this study is the lack of a full sleep habits inventory or polysomnography. Given the nature of this ancillary study, within the larger framework of its parent study, we were limited by participant burden to a subset of questions from the PSQI that were previously shown to be prevalent in older adults recruited for exercise trials and responsive to a physical activity intervention.51 Therefore, we cannot address the potential importance of primary sleep disorders as potential correlates of napping. However, our finding of an association of napping with obesity and diabetes implicates sleep apnea and thus nocturnal arousals as a possible cause. Finally, a possible confounding variable not defined in our study was medication usage, especially hypnotics. Some reports do not show a correlation of hypnotics with daytime sleepiness while others have shown correlations of these medications with disturbed sleep11,52 and napping status.
Self-reported sleep disorders are poorly correlated with polysomnography. Ideally, objective measures of nighttime sleep as well as napping should be used in future research. Recent studies, using objective assessment show under-reporting of napping behavior when compared to actigraphy and polysomnography measurements.8,29
It remains unclear whether napping should be an endorsed or discouraged practice, with reports that a short nap may be beneficial to cognitive status1,23,24,25 while others reporting that napping increases mortality rate.9,11,12 Our study provides further evidence that napping is a common practice of older adults and does not appear to worsen nighttime sleep. We provide evidence that napping behavior should always be assessed in sleep studies of older adults. It is also important for clinicians to ask about napping behavior and determine its relationship to daytime sleepiness and nighttime sleep before making clinical recommendations.
In summary, this is one of the first studies to show that those with diabetes have a higher risk of napping and subsequently sleep longer when day and nighttime sleep are considered together. It may be suggested that napping is an indicator of silent co-morbid disease complications. In our study population, nappers had a higher prevalence of diabetes mellitus, while cardiovascular disease has been extensively cited in the literature to be associated both with napping and daytime sleepiness, particularly in myocardial infarction survivors.17,18,19,20,21 While it remains unclear whether illness might increases actual sleep need, older individuals who are sicker may report more sleep per day due to an increase in their subjective need for sleep. As illness often reduces nighttime sleep quality, daytime napping may be an important mechanism for addressing their desire for more sleep.
Funding sources and related paper presentations: NIH training grant T32 AG 021885
CONFLICT OF INTEREST
Financial Disclosure: None.
Author Contributions:Jennifer L. Picarsic, MD: Primary investigator, Instrumental in study design and concept, acquisition and interpretation of data performed primary literature search, interpretation of data, primary writer of manuscript.
Nancy W. Glynn, PhD: Project manager, Instrumental in study design and concept, acquisition of subjects, analysis and interpretation of data, editor of manuscript.
Christopher A. Taylor, BS: Primary statistician, analysis and interpretation of data, editor of manuscript.
Stephanie Studenski, MD, MPH: Investigator, Instrumental in study design and concept, acquisition of subjects, editor of manuscript.
Suzanne E. Goldman, PhD: Instrumental in study concept, acquisition of data, editor of manuscript.
Jeffery Katula, PhD: Investigator, Instrumental in study design and concept, acquisition of subjects, editor of manuscript.
Anne B. Newman, MD, MPH: Investigator, Instrumental in study design and concept, acquisition of subjects, analysis and interpretation of data, primary editor of manuscript.