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Logo of annaldermaThis ArticleThis JournalAboutInformation for AuthorsOnline SubmissionAnnals of Dermatology
Ann Dermatol. 2009 February; 21(1): 98–101.
Published online 2009 February 28. doi:  10.5021/ad.2009.21.1.98
PMCID: PMC2883384

A Case of Varicella Combined with Hand-foot-mouth Disease in a Healthy Child

So Young Na, M.D., Young Min Son, M.D., Hye Young Lee, M.D., Jin Ok Baek, M.D., Joo Young Roh, M.D., and Jong Rok Lee, M.D.corresponding author


We report here on an 11-year-old child with a pustulovesicular eruption on her whole body, including her palms, soles and oral mucosa, and this was accompanied with fever. A serologic test was positive for IgM varicella zoster antibody and coxsackievirus A16 antibody. The histopathologic examination from the palm revealed intraepidermal pustules that showed neither inclusion bodies nor multinucleated giant cells. We made the final diagnosis, according to the serologic tests and histopathologic findings, as varicella combined with hand-foot-mouth disease caused by coxsackievirus A16 in a previously healthy child.

Keywords: Hand-foot-mouth disease, Varicella

Articles from Annals of Dermatology are provided here courtesy of Korean Dermatological Association and Korean Society for Investigative Dermatology