Search tips
Search criteria 


Logo of aaciBioMed CentralBiomed Central Web Sitesearchsubmit a manuscriptregisterthis articleAllergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
Allergy Asthma Clin Immunol. 2010; 6(Suppl 1): P31.
Published online 2010 May 12. doi:  10.1186/1710-1492-6-S1-P31
PMCID: PMC2874302

Treatment of initial allergic reactions to peanut inside and outside of health care facilities


Recent studies suggest increased admission rates for food-related anaphylaxis. The only effective treatment for anaphylaxis is prompt administration of epinephrine.


To characterize treatment practices of initial allergic reactions inside and outside health care facilities (HCF).


Individuals with an allergist-confirmed peanut allergy were recruited from the Montreal’s Children Hospital and Canadian food allergy advocacy organizations. Data were collected on initial allergic reactions to peanut and treatment inside and outside HCFs.


Of 751 individuals who had an allergic reaction to peanut, 613 responded (81.6%). Initial reactions were mild in 28.4% (95% CI, 25.0-32.1%), moderate in 50.6% (46.6-54.6%), and severe in 20.9% (17.8-24.3%). Average age of initial reaction was 2.1 years (2.0-2.3). Among participants, 11.6% (9.1-14.7%) were diagnosed with peanut allergy (based on skin and IgE testing) prior to the initial reaction. Of the 613 participants, 32.1% (28.5-36.0%) were treated in HCFs only, 51.7% (47.7-55.7) outside HCFs only, and 16.2% (13.4-19.3%) in both. 21.3% (17.0-26.3%) of all reactions treated in HCFs received epinephrine (table) versus only 3% (1.8-5.1%) treated outside. Of those with moderate or severe initial reactions, 58.2% (53.5-62.8%) were treated in HCFs, and 23.9% (19.1-29.6%) of these received epinephrine. See table table11.


Almost 50% of individuals with potentially life-threatening initial reactions are not treated in HCFs. Further, for those with moderate and severe reactions treated in HCFs, there is substantial underuse of epinephrine. Thus, it is crucial to establish, distribute, and monitor treatment guidelines that would improve treatment practices of food-related allergic reactions.

Articles from Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology are provided here courtesy of BioMed Central