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Cover photograph (Copyright © 2010, American Society for Microbiology. All Rights Reserved.): Rickettsia rickettsii showing intracellular movement and cell-to-cell dissemination by actin-based motility as visualized by staining with rhodamine-phalloidin. Disruption of the Sca2 autotransporter protein inhibits actin comet tail formation and reduces virulence in a guinea pig model system. (See related article on p. 2240.)

Infect Immun. 2010 May; 78(5): Cover