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Logo of expclincardiolExperimental and Clinical Cardiology HomepageSubscription PageSubmissions Pagewww.pulsus.comExperimental and Clinical Cardiology
Exp Clin Cardiol. 2001 Summer; 6(2): 59–60.
PMCID: PMC2859006

Third International Symposium on Myocardial Cytoprotection: From Basic Science to Clinical Perspectives

September 28 to 30, Pécs, Hungary
Elizabeth Rőth, MD PhD DSc

We were honoured to have the opportunity to arrange the Third International Symposium on Myocardial Cytoprotection (ISMC) under the auspices of the Experimental Section of the Hungarian Society of Cardiology. As always, the venue was Pécs, home to the oldest university in Hungary. Our department, the Department of Experimental Surgery, affiliated with the Medical Centre of Pécs University, hosted the meeting. We tried our utmost to create a forum for discussion and exchange of ideas and the latest findings in the field of cardioprotection. Topics under discussion ranged from the latest findings on cardiac adaptation, to reperfusion injury and cardiac apoptosis, to the development of new surgical approaches with cardioprotection in mind.

A total of 86 abstracts were received. Sixty-one papers were accepted for presentation: 47 for oral presentation and 14 for poster presentation. Eleven distinguished researchers from across Europe and the United States were invited to present their research at the meeting. On Thursday, September 28, a satellite meeting entitled “Off-pump surgery. Is myocardial protection still necessary?”, organized in collaboration with Dr Amrani and his colleagues from the Royal Brompton & Harefield NHS Trust (UK), was held, at which more than 10 lectures were presented regarding this topic. The satellite meeting focused on the learning curve, hemodynamics, anesthetic problems and patient recovery using this technique. Colleagues from Croatia and Hungary also presented their results regarding off-pump surgery.

The core meeting was arranged between Thursday late afternoon and Saturday (September 28 to 30). Six sessions were designated for oral presentation and two parallel sessions for poster presentation. The sessions of the third ISMC meeting are summarized below:

  • Session 1: coronary circulation, regulatory mechanisms, endothelial mediators and dysfunction (mechanism of calcium-dependant vasodilation, nitric oxide and endothelin interactions).
  • Session 2: preconditioning, from the basics to clinical practice (possible therapeutic exploitations, nitric oxide in cardioadaptation, protection in the developing heart).
  • Session 3: oxidative stress and reperfusion injury (new approaches to reperfusion injury, oxidative stress in various pathophysiological settings).
  • Session 4: intracellular changes, alterations in myocardial performance (role of serine protease in myocardial performance, Na+/K+ ATPase and stunning).
  • Session 5: failing heart, diabetes, cardiomyopathy (the diabetic heart and Ca2+-regulation, protein kinases and susceptibility to arrhythmia).
  • Session 6: hemorrheology, vascular pathology (hemorrheological parameters and ischemic heart disease).

The high standard of the oral presentation provided a good base for fruitful scientific discussions. The poster session was arranged for Friday, September 29, under the excellent guidance of Prof Eric Roth, Prof Ágnes Végh, Prof Attila Ziegelhöffer and Nándor Marczin. We sincerely hope that the scientific as well as the various social programs were to all participants’ tastes.

I thank all my colleagues in the local organizing committee (J Lantos, MT Jaberansari, Z Szántó, A Ferencz, B Borsiczky) who greatly contributed to the making of this symposium and strove to ensure a memorable time for all participants. I also thank all my friends, colleagues and fellow researchers for attending the meeting.

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