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Curr Oncol. 2010 April; 17(2): 5.
PMCID: PMC2854637

Reply from Dr. Luis Souhami

We thank Drs. Tokgöz and Erol for their interest in our review paper on the conservative management of invasive bladder cancer and for their comments. They specifically refer to the potential prognostic value of lymphovascular space invasion for cancer-specific survival in patients undergoing radical cystectomy 1. Lymphovascular space invasion has been shown to be of prognostic value in other malignancies, and we agree with the authors that it is likely to be predictive of survival in bladder cancer and that further studies are needed to better clarify its potential role as a stratification factor.

REFERENCES

1. Türkölmez K, Tokgöz H, Reşorlu B, Köse K, Bedük Y. Muscleinvasive bladder cancer: predictive factors and prognostic difference between primary and progressive tumors. Urology. 2007;70:477–81. [PubMed]

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