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Students in the health professions are often not taught the skills necessary to critically and accurately evaluate published drug studies, which are of increasing importance. The objective of this project was to develop, refine, and test a computer assisted instructional program designed to educate pharmacy and medical students to critically evaluate published drug efficacy studies. The interactive program thus far contains 10 main sections and 10 subsections. It is designed to serve as a stand-alone educational program which students can complete at their own pace. The software has currently been used and evaluated by second professional year pharmacy students using a pre-test/post-test design and a comparison group which did not receive similar instruction. Student comments have been positive overall, and learning was significantly increased by the program. The program will be further utilized and tested by second year medical students and Doctor of Pharmacy degree students.