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Cover photograph (Copyright © 2010, American Society for Microbiology. All Rights Reserved.): Localization of heme-regulated inhibitor (HRI) kinase to stress granules. (Top) Merged image of HeLa cells undergoing arsenite-induced stress. The stress granule marker G3BP1 (green) and eukaryotic translation initiation factor 2 kinase HRI (pink) are detected by indirect immunofluorescence. White foci represent an overlap of G3BP1 and HRI in cytoplasmic stress granules. (Bottom) Zoom (×2) of the cytoplasmic region indicated by the white box (top) showing HRI, G3BP1, and merged channels, respectively. (See related article on page 2006.)

Mol Cell Biol. 2010 April; 30(8): Cover