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Tissue Antigens. 2010 April; 75(4): 291–455.
PMCID: PMC2848993
Copyright © 2010 John Wiley & Sons A/S
Nomenclature for factors of the HLA system, 2010
S G E Marsh, E D Albert, W F Bodmer, R E Bontrop, B Dupont, H A Erlich, M Fernández-Viña, D E Geraghty, R Holdsworth, C K Hurley, M Lau, K W Lee, B Mach, M Maiers, W R Mayr, C R Müller, P Parham, E W Petersdorf, T Sasazuki, J L Strominger, A Svejgaard, P I Terasaki, J M Tiercy, and J Trowsdale
SGE Marsh, Anthony Nolan Research Institute, London, UK (Chairman)
ED Albert, Munich, Germany
WF Bodmer, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, UK
RE Bontrop, Biomedical Primate Research Centre, Rijswijk, The Netherlands
B Dupont, Sloan-Kettering Institute for Cancer Research, New York, USA
HA Erlich, Roche Molecular Systems, Alameda, USA
M Fernández-Viña, MD Anderson, Houston, USA
DE Geraghty, Fred Hutchinson Cancer Center, Seattle, USA
R Holdsworth, Victorian Transplantation and Immunogenetics Service, Melbourne, Australia
CK Hurley, Georgetown University, Washington, USA
M Lau, UCLA School of Medicine, Los Angeles, USA
KW Lee, Hallym University, Anyang City, South Korea
B Mach, University of Geneva, Geneva, Switzerland
M Maiers, National Marrow Donor Program, Minneapolis, USA
WR Mayr, Medical University of Vienna, Vienna, Austria
CR Müller, Zentrales Knochenmarkspender-Register, Ulm, Germany
P Parham, Stanford University School of Medicine, Stanford, USA
EW Petersdorf, Fred Hutchinson Cancer Center, Seattle, USA
T Sasazuki, International Medical Centre of Japan, Tokyo, Japan
JL Strominger, Harvard University, Cambridge, USA
A Svejgaard, State University Hospital, Copenhagen, Denmark
PI Terasaki, Los Angeles, USA
JM Tiercy, Hôpital Cantonal Universitaire, Geneva, Switzerland
J Trowsdale, Cambridge University, Cambridge, UK
Prof Steven GE Marsh, Anthony Nolan Research Institute, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, United Kingdom. Tel. +44 20 7284 8321; Fax: +44 20 7284 8331; e-mail: steven.marsh/at/ucl.ac.uk; URLs: hla.alleles.org; www.ebi.ac.uk/imgt/hla/
Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
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The WHO Nomenclature Committee for Factors of the HLA System met following the 14th International HLA and Immunogenetics Workshop in Melbourne, Australia in December 2005 and Buzios, Brazil during the 15th International HLA and Immunogenetics Workshop in September 2008. This report documents the additions and revisions to the nomenclature of HLA specificities following the principles established in previous reports (1–18).
1. Naming of HLA genes and alleles
A number of HLA gene fragments have been reported and named. These are HLA-T previously known as HLA-16 (19), HLA-U previously known as HLA-21 (19), HLA-V previously known as HLA-75 (19), HLA-W previously known as HLA-80 (19), HLA-P previously known as HLA-90 (19) and HLA-Y previously known as HLA-BEL/COQ/DEL (20, 21). A full list of all recognised HLA genes is given in Table 1.
Table 1
Table 1
Names for genes in the HLA region
a. Conditions for acceptance of new allele sequences
As emphasised in previous reports, there are required conditions for acceptance of new sequences for official names.
  • Where a sequence is obtained from cDNA, or where PCR products are subcloned prior to sequencing, several clones should have been sequenced.
  • Sequencing should always be performed in both directions.
  • If direct sequencing of PCR amplified material is performed, products from at least two separate PCR reactions must have been sequenced.
  • In individuals who are heterozygous for a locus, and where one of the alleles is novel, the novel allele must be sequenced in isolation from the second allele. Thus an allele sequence that is derived using a sequence-based typing (SBT) methodology, where both alleles of a heterozygous individual are sequenced together, is insufficient evidence for assignment of an official designation.
  • Sequence derived solely from the primers used to amplify an allele must not be included in the submitted sequence.
  • Where possible, a novel sequence should be confirmed by typing of genomic DNA using a method such as PCR-SSOP or PCR-SSP. Where a new sequence contains either a novel mutation or a previously unseen combination of nucleotides (sequence motif), this must be confirmed by a DNA typing technique. This may require the use of newly designed probes or primers to cover the new mutation; these reagents should also be described.
  • An accession number in a databank should have been obtained. Sequences may be submitted to the databases online at the following addresses:
  • Full-length sequences are preferable though not essential; the minimum requirements are complete exons 2 and 3 for an HLA class I sequence and complete exon 2 for an HLA class II sequence.
  • Where a novel sequence differs only within an intron or other non-coding part of the gene, a full-length sequence must be obtained, which covers all coding and non-coding regions. In the absence of a full-length genomic sequence from the most closely related allele that is identical in its exon sequence, it may be required that this also be sequenced and submitted before a name can be assigned to the novel sequence.
  • Where possible, a paper in which the new sequence is described should be submitted for publication. Copies of draft publications can be submitted to the database by email or FAX.
  • Sequences derived solely from tumour material will not be considered for nomenclature.
  • The complete HLA type for the HLA-A, -B and -DRB1 genes should be submitted for the material in which a novel allele has been defined. In addition the sample should have been characterised for the second allele at the locus of interest in a heterozygous individual.
  • DNA or other material, preferably cell lines, should, wherever possible, be made available in a publicly accessible repository or alternatively, at least in the originating laboratory. The WHO Nomenclature Committee will maintain documentation on this material.
  • Submission of a sequence to the WHO Nomenclature Committee should be performed using the online submission tool available at www.ebi.ac.uk/imgt/hla/subs/submit.html. Researchers are expected to complete a questionnaire relating to the sequence and provide a comparison of their new sequence with known related alleles. If the sequence cannot be submitted using the online web tools, researchers should contact hla/at/alleles.org directly for details of alternative submission methods.
Although at present it is only a recommendation that full-length sequences of the coding region of novel alleles be submitted it was widely felt that in the future this should become a requirement for submission. Such requirement would remove many of the currently encountered ambiguities in the assignment of names to alleles for which partial sequences have been submitted and should not be burdensome as sequencing techniques have improved substantially since the submission conditions were first devised. In cases where novel mutations or polymorphisms are detected in non-coding regions of the gene, it will be a requirement that full-length sequences be submitted of both the novel allele and its most closely related allele.
It should be noted with some caution that cells from which only partial sequences have been obtained may later be shown to have different or novel alleles when further sequencing is performed. This is of particular importance in cases where partial sequences of what appears to be the same allele have been obtained from several different cells. In such cases, all cells studied have been listed in this report.
Current practice is that official designations will be promptly assigned to newly described alleles in periods between Nomenclature Committee meetings, provided that the submitted data and its accompanying description meet the criteria outlined above. A list of the newly reported alleles is published each month in nomenclature updates in the journals Tissue Antigens, Human Immunology and the International Journal of Immunogenetics. The listing of references to new sequences does not imply priority of publication. The use of numbers or names for alleles, genes or specificities which pre-empt assignment of official designations by the Nomenclature Committee is strongly discouraged.
The list of those genes in the HLA region considered by the WHO Nomenclature Committee is given in Table 1.
b. New Allele Sequences
A total of 2558 HLA alleles have been named since the last report (18). The newly named alleles are shown in bold typeface in Tables 2 to ​to11.11. For HLA class I, 616 HLA-A, 913 HLA-B, 446 HLA-C, four HLA-E, 19 HLA-F, 31 HLA-G, 12 HLA-H, nine HLA-J, six HLA-K, five HLA-L, four HLA-P and three HLA-V alleles were named, making a total of 3249 class I alleles with official names. For HLA class II, 368 HLA-DRB1, 12 HLA-DRB3, one HLA-DRB4, one HLA-DRB5, seven HLA-DQA1, 45 HLA-DQB1, six HLA-DPA1, 22 HLA-DPB1, one HLA-DMB and four HLA-DOA alleles were named, making a total of 1198 class II alleles with official names. Eleven MICA alleles were named bringing their total to 68 and 12 MICB alleles bringing their total to 30 alleles, see Table 12. The total number of alleles at each locus assigned with official names as of 31st December 2009 is given in Table 13. A full list of all allele names that have been deleted is given in Table 14.
Table 2
Table 2
Designations of HLA-A alleles
Table 11
Table 11
Designations of TAP alleles
Table 12
Table 12
Designations of MICA and MICB alleles
Table 13
Table 13
Numbers of alleles with official names at each locus by 31st December 2009
Table 14
Table 14
List of allele names that have been deleted
Table 3
Table 3
Designations of HLA-B alleles
Table 4
Table 4
Designations of HLA-C, -E, -F and -G alleles
Table 5
Table 5
Designations of HLA-H, -J, -K, L, P, and -V alleles
Table 6
Table 6
Designations of HLA-DRA and -DRB alleles
Table 8
Table 8
Designations of HLA-DPA1 and -DPB1 alleles
Table 9
Table 9
Designations of HLA-DOA and -DOB alleles
Table 10
Table 10
Designations of HLA-DMA and -DMB alleles
In February 2005 the allele A*30:14L was named. The allele has a mutation in codon 164 encoding a cysteine residue contributing to a structurally critical disulphide bond in the α2 domain of the HLA molecule. Expression studies performed on cells with this allele showed its protein to have a much-reduced expression compared to normal, and the allele name was thus given the suffix ‘L’ to indicate this low expression. Since then several other alleles have been reported that have also lost one of the two cysteine residues (position 101 and 164) that form the α2 domain disulphide bond. It has not, however, been possible to ascertain the expression status of these alleles, due to a lack of viable material. The Nomenclature Committee considered the naming of these alleles during the 14th HLA and Immunogenetics Workshop. As a result of these discussions, it was decided to introduce an additional suffix, Q, to indicate a ‘Questionable’ expression level. The first seven alleles to receive this suffix have been named and are included in this report, A*23:19Q, A*32:11Q, B*13:08Q, B*35:65Q, B*39:38Q, C*02:25Q and C*03:22Q. It is anticipated that when further examples of these alleles are described, their expression status will be determined and the suffix changed accordingly.
As the database of HLA allele sequences has expanded, it has become increasingly difficult to maintain consistent linkage between allele names assigned on the basis of nucleotide sequences and the serological profiles of the encoded proteins. These difficulties are in part technological and in part due to the inherent biological properties of the HLA system. In the first category there is the increasing emphasis on DNA technology and consequent lack of a serological description for many newly discovered HLA alleles. In the second category is the finding that a newly defined antigen does not comfortably fit within any known serological grouping. This is especially true of the HLA-DRB1*03, *11, *13, *14 and *08 family of alleles, for which the description of new alleles has revealed a continuum of allelic diversity rather than five discrete sub-families. It should be stressed that, although a goal is to indicate the serological grouping into which an allele will fall, this is not always possible. Most importantly the allele name should be seen as no more than a unique designation.
2. Serological specificities associated with alleles
Where this information is known, lists of the serological specificities or antigens associated with the alleles, is given in Tables 2–7. In most cases these data are based on the serological typing obtained for the cells that were sequenced for the individual alleles and from information submitted to the Committee. In many cases no serological information is available and the entry in the table has been left blank. This is also true for cases when the serological pattern associated with an expressed allele does not correspond to a single defined specificity. A comprehensive dictionary of antigen and allele equivalents is published periodically by the World Marrow Donor Association (WMDA) Quality Assurance Working Group on HLA Serology to DNA Equivalents (22–26). Where additional or superior serological data are available from the dictionary, this has been included in Tables 2–7 and the source of this information indicated. A full list of all officially named serological specificities is given in Table 15. The specificity B82 was assigned following the 14th International HLA and Immunogenetics Workshop in 2005 having been clearly identified as a novel antigen in a number of UCLA cell exchanges.
Table 7
Table 7
Designations of HLA-DQA1 and -DQB1 alleles
Table 15
Table 15
List of all recognised serological and cellular HLA specificities
3. Introduction of colon delimited HLA allele names
The convention of using a four-digit code to distinguish HLA alleles that differ in the proteins they encode was introduced in the 1987 Nomenclature Report (8). Since that time additional digits have been added, and currently an allele name may be composed of four, six or eight digits dependent on its sequence.
The first two digits describe the allele family, which often corresponds to the serological antigen carried by the allotype. The third and fourth digits are assigned in the order in which the sequences have been determined. Alleles whose numbers differ in the first four digits must differ by one or more nucleotide substitutions that change the amino-acid sequence of the encoded protein. Alleles that differ only by synonymous nucleotide substitutions within the coding sequence are distinguished by the use of the fifth and sixth digits. Alleles that only differ by sequence polymorphisms in introns or in the 5′ and 3′ untranslated regions that flank the exons and introns are distinguished by the use of the seventh and eight digits.
In 2002 we faced the issue of the A*02 and B*15 allele families having more than 100 alleles (17). At that time the decision taken was to name further alleles in these families in the rollover allele families A*92 and B*95 respectively. For HLA-DPB1 alleles, it was decided to assign new alleles within the existing system, hence once DPB1*9901 had been assigned, the next allele would be assigned DPB1*0102, followed by DPB1*0203, DPB1*0302 etc.
When these conventions were adopted it was anticipated that the nomenclature system would accommodate all the HLA alleles likely to be sequenced. Unfortunately this is not the case, as the number of alleles for certain genes is fast approaching the maximum possible with the current naming convention.
With the ever increasing number of HLA alleles described it has been decided to introduce colons (:) into the allele names to act as delimiters of the separate fields. To facilitate the transition from the old to the new nomenclature, a single leading zero must be added to all fields containing the values 1 to 9 but beyond that no leading zeros are allowed. This will help to lessen any confusion in the conversion to the new style of nomenclature.
Hence
A*01010101 becomes A*01:01:01:01
A*02010102L becomes A*02:01:01:02L
A*260101 becomes A*26:01:01
A*3301 becomes A*33:01
B*0808N becomes B*08:08N
DRB1*01010101 becomes DRB1*01:01:01:01
For allele families that have more than 100 alleles such as the A*02 and B*15 groups it will be possible to encode these in a single series. Thus the A*92 and B*95 alleles have now been renamed in to the A*02 and B*15 allele series. For example:
A*9201 becomes A*02:101
A*9202 becomes A*02:102
A*9203 becomes A*02:103 etc
B*9501 becomes B*15:101
B*9502 becomes B*15:102
B*9503 becomes B*15:103 etc
The names A*02:100 and B*15:100 will not be assigned. In cases of other allele families where the number of alleles reaches 100 these will be numbered sequentially, for example A*24:99 will be followed by A*24:100.
The DPB1 allele names that have been previously assigned names within the existing system have also be renamed, for example:
DPB1*0102 becomes DPB1*100:01
DPB1*0203 becomes DPB1*101:01
DPB1*0302 becomes DPB1*102:01
DPB1*0403 becomes DPB1*103:01
DPB1*0502 becomes DPB1*104:01 etc
The ‘w’ will be removed from the HLA-C allele names, but will be retained in the HLA-C antigen names, to avoid confusion with the factors of the complement system and epitopes on the HLA-C molecule often termed C1 and C2 that act as ligands for the Killer-cell Immunoglobulin-like Receptors.
Cw*0103 becomes C*01:03
Cw*020201 becomes C*02:02:01
Cw*07020101 becomes C*07:02:01:01 etc
Details of the new format allele names are given in column 1 of Tables 2–12, with the previous name listed in column 2. These changes to the HLA Nomenclature will be officially introduced in April 2010. A full listing of old and new HLA allele names will be made available through the IMGT/HLA Database (www.ebi.ac.uk/imgt/hla) (27, 28) and be implemented with the April 2010 release of the database.
4. Reporting of ambiguous HLA allele typing
The level of resolution achieved by many of the HLA typing technologies employed today does not always allow for a single HLA allele to be unambiguously assigned. Often it is only possible to resolve the presence of a number of closely related alleles. This is referred to as an ambiguous ‘string’ of alleles. In addition, typing strategies are frequently aimed at resolving alleles that encode differences within the peptide binding domains, but fail to exclude those that differ elsewhere. For some purposes it is helpful to provide codes that aid the reporting of certain ambiguous alleles ‘strings’. The decision was taken to introduce codes to allow for the easy reporting of:
a. HLA alleles that encode for identical peptide binding domains
HLA alleles having nucleotide sequences that encode the same protein sequence for the peptide binding domains (exon 2 and 3 for HLA class I and exon 2 only for HLA class II alleles) will be designated by an upper case ‘P’ which follows the allele designation of the lowest numbered allele in the group.
For example the string of allele names below share the same α1 and α2 domain protein sequence encoded by exons 2 and 3.
A*02:01:01:01/A*02:01:01:02L/A*02:01:01:03/A*02:01:02/A*02:01:03/A*02:01:04/A*02:01:05/A*02:01:06/A*02:01:07/A*02:01:08/A*02:01:09/A*02:01:10/A*02:01:11/ A*02:01:12/A*02:01:13/A*02:01:14/A*02:01:15/A*02:01:17/A*02:01:18/A*02:01:19/A*02:01:21/A*02:01:22/A*02:01:23/A*02:01:24/A*02:01:25/A*02:01:26/A*02:01:27/ A*02:01:28/A*02:01:29/A*02:01:30/A*02:01:31/A*02:01:32/A*02:01:33/A*02:01:34/A*02:01:35/A*02:01:36/A*02:01:37/A*02:01:38/A*02:01:39/A*02:01:40/A*02:01:41/ A*02:01:42/A*02:09/A*02:66/A*02:75/A*02:89/A*02:97:01/ A*02:97:02/A*02:132/A*02:134/A*02:140
This string can be reduced to A*02:01P
b. HLA alleles that share identical nucleotide sequences for the exons encoding the peptide binding domains
HLA alleles that have identical nucleotide sequences for the exons encoding the peptide binding domains (exon 2 and 3 for HLA class I and exon 2 only for HLA class II alleles) will be designated by an upper case ‘G’ which follows the allele designation of the lowest numbered allele in the group.
For example the string shown below consists of alleles that have identical nucleotide sequences in exons 2 and 3.
A*02:01:01:01/A*02:01:01:02L/A*02:01:01:03/A*02:01:08/A*02:01:11/A*02:01:14/A*02:01:15/A*02:01:21/A*02:09/A*02:43N/A*02:66/A*02:75/A*02:83N/A*02:89/A*02:97:01/A*02:97:02/A*02:132/A*02:134/A*02:140
This string can be reduced to A*02:01:01G
These reporting codes will be implemented in April 2010 and will be made available through the IMGT/HLA Database (www.ebi.ac.uk/imgt/hla) (27, 28) and will be implemented with the April 2010 release of the database.
5. Gene and protein nomenclature
Discussions took place on the use of nomenclature for defining HLA allele sequences at the gene and protein level. The committee recommended the use of standard genetic nomenclature where gene symbols are in uppercase and italicised and protein symbols are the same as the gene symbols but are not italicised. Using this approach it is possible to discriminate between an allele of the HLA-A gene, for example A*03:01 and the expressed protein product of the same gene A*03:01.
Additionally it was recommended that when reporting an ambiguous string of HLA alleles, a forward slash (/) should be used as the separator to indicate ‘or’. When reporting genotypes it was recommended to use a comma (,) to indicate ‘and’. Hence an HLA type may be reported as:
A*02:01/02:09, 03:01; B*07:02, 15:02/15:73; C*03:03, 07:02
6. The IMGT/HLA Sequence Database
The IMGT/HLA Sequence Database continues to act as the official repository for HLA sequences named by the WHO Nomenclature Committee for Factors of the HLA System (27, 28). The database contains sequences for all HLA alleles officially recognised by the WHO Nomenclature Committee for Factors of the HLA System and provides users with online tools and facilities for their retrieval and analysis. These include allele reports, alignment tools, and detailed descriptions of the source cells. The online IMGT/HLA submission tool allows both new and confirmatory sequences to be submitted directly to the WHO Nomenclature Committee. New releases of the database are made every three months, in January, April, July and October, with the latest version (release 2.28.0 January 2010) containing 4447 HLA alleles. The database may be accessed via the worldwide web at www.ebi.ac.uk/imgt/hla.
The IMGT/HLA Database is currently supported by the following organisations: Histogenetics, Abbott, Biotest, Invitrogen, One Lambda, Olerup SSP, Gen-Probe, The Anthony Nolan Trust (ANT), The American Society for Histocompatibility and Immunogenetics (ASHI), The European Federation for Immunogenetics (EFI), Innogenetics, BAG Healthcare, Be the Match Foundation and the National Marrow Donor Program.
Acknowledgments
The Committee would like to thank James Robinson, Kavita Mistry, Matthew Waller and Sylvie Fail for their work with the IMGT/HLA Sequence database, and Kavita Mistry for her help in the preparation of tables for this report. Also thanked are Rodrigo Lopez, Hamish McWilliam and Peter Stoehr and the staff at the European Bioinformatics Institute for their continued support of the IMGT/HLA Database. We would also like to thank the many organisations that provide financial support for the IMGT/HLA database and Angie Dahl of the ‘Be the Match Foundation’ for her work in soliciting and coordinating the funding of this project.
List of committee members involved in preparing this report:
SGE Marsh, Anthony Nolan Research Institute, London, UK (Chairman)
ED Albert, Munich, Germany
WF Bodmer, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, UK
B Dupont, Sloan-Kettering Institute for Cancer Research, New York, USA
HA Erlich, Roche Molecular Systems, Alameda, USA
M Fernández-Viña, MD Anderson, Houston, USA
DE Geraghty, Fred Hutchinson Cancer Center, Seattle, USA
R Holdsworth, Victorian Transplantation and Immunogenetics Service, Melbourne, Australia
CK Hurley, Georgetown University, Washington, USA
M Lau, UCLA School of Medicine, Los Angeles, USA
KW Lee, Hallym University, Anyang City, South Korea
B Mach, University of Geneva, Geneva, Switzerland
M Maiers, National Marrow Donor Program, Minneapolis, USA
WR Mayr, Medical University of Vienna, Vienna, Austria
CR Müller, Zentrales Knochenmarkspender-Register, Ulm, Germany
P Parham, Stanford University School of Medicine, Stanford, USA
EW Petersdorf, Fred Hutchinson Cancer Center, Seattle, USA
T Sasazuki, International Medical Centre of Japan, Tokyo, Japan
JL Strominger, Harvard University, Cambridge, USA
A Svejgaard, State University Hospital, Copenhagen, Denmark
PI Terasaki, Los Angeles, USA
JM Tiercy, Hôpital Cantonal Universitaire, Geneva, Switzerland
J Trowsdale, Cambridge University, Cambridge, UK
Co-opted members:
RE Bontrop, Biomedical Primate Research Centre, Rijswijk, The Netherlands
Footnote:
New sequences should be communicated to Prof Steven Marsh via the sequence submission tool of the IMGT/HLA Database to receive official names, www.ebi.ac.uk/imgt/hla.
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163. Lazaro AM, Hwang WY, Yeoh AE, Ng J, Posch PE. Characterization of new HLA-B and -DRB1 alleles from Singapore. Tissue Antigens. 2009;73:75–6. [PubMed]
164. Chen Q, Zou H, Xu XH, et al. Characterization of HLA-B*5516, -B*1313, -B*9512, and -DRB1*1457 alleles identified in a southwest Chinese population. Tissue Antigens. 2006;68:339–43. [PubMed]
165. Altermann WW, Wahle A, Seliger B, Schlaf G. A novel HLA-B70 (B*9514) allele with an amino acid substitution (alanine to glycine at protein position 139) in a Caucasian heart allograft recipient. Tissue Antigens. 2006;68:185–7. [PubMed]
166. An SP, Yan LN, Li SY, et al. HLA-B*9518 allele identified in the Chinese population. Tissue Antigens. 2007;69:363–5. [PubMed]
167. Chu CC, Chen YF, Lee HL, Lin CY, Lin M. Identification of HLA-B*9521 in Taiwan. Tissue Antigens. 2009;74:445–6. [PubMed]
168. Balas A, Sanchez-Gordo F, Garcia-Sanchez F, Prat I, Vicario JL. HLA-B*9523 increases the extremely high B*15-group polymorphism. Tissue Antigens. 2007;69:620–1. [PubMed]
169. Zhu FM, He JJ, He J, Yan LX. A novel HLA-B*15 allele, B*9524, identified by sequence-based tying in the Chinese population. Tissue Antigens. 2007;70:521–2. [PubMed]
170. Wang QS, Li JP, Chen Y, Li XF, Liu XZ. Identification of a novel HLA-B allele HLA-B*9526 in a Chinese donor. Tissue Antigens. 2009;73:280–1. [PubMed]
171. Zhu FM, He J, Zhang W, Yan LX. Identification of a novel HLA-B*15 allele, B*9529, in the Chinese population. Tissue Antigens. 2008;71:254–5. [PubMed]
172. Yan LX, Zhu FM, He JJ, Xu XG. A novel HLA-B*15 allele, B*9534, identified by sequence-based typing in the Chinese population. Tissue Antigens. 2008;71:256–7. [PubMed]
173. Yan LX, Zhu FM, Zhang W, He J. Two novel alleles HLA-B*9536 and B*4612 were identified in a healthy Chinese individual. Tissue Antigens. 2008;71:573–5. [PubMed]
174. Zou HY, Li Z, Jin SZ, Cheng X, Cheng LH. A frame shift due to a two-nucleotide deletion results in an HLA-B null allele, B*9549N. Tissue Antigens. 2009;74:447–9. [PubMed]
175. Alaez C, Munguia A, Flores AH, Gomez K, Gorodezky C. Identification of B*9550, a novel B*15 allele, in a Mexican bone marrow donor from Veracruz State. Tissue Antigens. 2009;73:614–6. [PubMed]
176. Dubois V, Favre-Victoire I, Giannoli C. Three new HLA-B alleles determined by sequence-based typing: B*9551, B*5161 and B*5317. Tissue Antigens. 2009 in press. [PubMed]
177. Elsner HA, Baengeroth K, Blasczyk R. The nature of introns 4–6 suggests reduced lineage specificity in HLA-B alleles. Genes Immun. 2003;4:391–401. [PubMed]
178. Witter K, Conrad H, Bernhard H, Albert T, Kauke T. HLA-B*1832, a novel B allele was found through high-resolution HLA typing of a Spanish blood donor. Tissue Antigens. 2009;74:170–2. [PubMed]
179. Jeong SM, Hur SS, Kwon OJ, Nah SY. A new HLA-B*27 allele, HLA-B*270402, identified by sequence-based typing. Tissue Antigens. 2006;67:340–1. [PubMed]
180. Heymann GA, Hoppe B, Schonemann C, Lassahn A, Salama A. A novel HLA-B*270509 variant escaping detection by PCR-SSO-based histotyping. Tissue Antigens. 2005;66:702–3. [PubMed]
181. Vidan-Jeras B, Kunilo S, Fae I, Kandus A, Fischer GF. A novel HLA-B*2730 allele found in a Slovene patient affected with IgA nephropathy. Int J Immunogenet. 2006;33:371–3. [PubMed]
182. Witter K, Albert T, Volgger A, Zahn R, Scholz S. Routine HLA sequence-specific-oligonucleotide typing and confirming sequence-based typing of a prospective bone marrow donor identified a novel B*27 allele, HLA-B*2734. Tissue Antigens. 2006;68:527–8. [PubMed]
183. Li Z, Zou HY, Shao CP, Tang S, Wang DM. Identification of a novel HLA-B*56 allele, B*5618 and an extension of B*2736 by sequence-based typing. Tissue Antigens. 2007;69:365–6. [PubMed]
184. Chen MJ, Yang TC, Chu CC, et al. Detection of a novel HLA-B*27 allele, B*2740, in Taiwanese volunteer bone marrow donors by sequence-based typing: curiosity rewarded. Int J Immunogenet. 2009;36:207–11. [PubMed]
185. Vidan-Jeras B, Ambroz N, Fae I, Kemperle I, Fischer G. HLA-B*350802, a novel allele, which has arisen by silent mutation at codon 67. Tissue Antigens. 2007;69:363. [PubMed]
186. Lee KW. A novel hybrid allele (B*3563) originated from B*350101 and B*4001-like alleles. Tissue Antigens. 2007;70:260–2. [PubMed]
187. Hwang SH, Lim YS, Kwon OJ, Heo YS, Oh HB. Structural aspects the of B*3564 molecule, a novel HLA-B*35 allele identified by sequence-based typing. Tissue Antigens. 2006;68:90–1. [PubMed]
188. Elsner HA, Horn PA, Schoenemann C, Altermann WW, Blasczyk R. Aberrant expression of HLA-B*3565Q is associated with a disrupted disulfide bond. Immunogenetics. 2006;58:929–31. [PubMed]
189. Schlaf G, Erhuma ME, Seliger B, Foell J, Altermann WW. A novel HLA-B*35 (B*3570) allele of a Caucasian family differing with one amino acid mismatch from HLA-B*3503 allele in exon 4. Tissue Antigens. 2007;70:72–3. [PubMed]
190. Aubert V, Mayerat C, Lopez N, Pantaleo G. Sequence analysis of the novel HLA-B35 (B*3576) allele in an African individual. Tissue Antigens. 2007;70:439–41. [PubMed]
191. Aureli A, Liberatore G, Papola F, Adorno D, Piancatelli D. Identification of a novel HLA-B allele, HLA-B*3580, with possible implication in transplantation and CTL response. Tissue Antigens. 2008;71:90–1. [PubMed]
192. Brixner V, Steffen B, Seidl C, Seifried E. Sequencing-based typing reveals the novel HLA-B*3581 allele in a voluntary stem cell donor. Tissue Antigens. 2009 in press.
193. Phipps M, Jinam T. A new HLA-B*35 allele, B*3589, detected in a Malaysian individual. Tissue Antigens. 2009;73:279–80. [PubMed]
194. Jin SZ, Li Z, Zou HY, Cheng X, Cheng LH, Wang DM. A novel HLA-B*37 allele, B*370105, was identified in a Chinese Han individual. Tissue Antigens. 2009;74:344–5. [PubMed]
195. Frison S, Longhi E. Espadas de Arias A, Andreini E, Poli F, Scalamogna M. Characterization of the novel allele HLA-B*3710. Tissue Antigens. 2006;67:173–4. [PubMed]
196. Lin W, Shan X, Zhang Z. Identification of a novel HLA-B allele, HLA-B*3713, in a Chinese individual. Tissue Antigens. 2008;72:177–9. [PubMed]
197. Emmerich F, Schonemann C, Diederich G, Salama A. Haplotype-specific sequencing reveals a novel HLA-B*37 allele, B*3714. Tissue Antigens. 2009;73:67. [PubMed]
198. Aureli A, Piancatelli D, Ozzella G, Libertore G, Piazza A, Adorno D. B*3812: a new HLA-B38 variant identified by sequence-based typing. Tissue Antigens. 2006;68:91–3. [PubMed]
199. Cheng LH, Zhu WG, Lan YX, Jin SZ, Zou HY. Full length sequence of a novel HLA-B*3818 allele differs from HLA-B*380201 allele in exon 4 and intron 5. Tissue Antigens. 2009;74:439–40. [PubMed]
200. Yan LX, Zhu FM, Lv QF, Zhang W, He J. Identification of a novel HLA-B*39 allele, B*3936, by sequencing-based typing. Tissue Antigens. 2006;67:341–2. [PubMed]
201. Paturel L, Bera O, Favre-Victoire I, Dubois V. Identification of a new HLA-B*40 variant, B*400204, by sequence-based typing in a Martinican individual. Tissue Antigens. 2009;74:345–7. [PubMed]
202. Shan X, Gao G, He X, Wu G, Zhang Z. Identification of a novel HLA-B allele HLA-B*4059 in a Chinese bone marrow donor. Tissue Antigens. 2006;67:339–40. [PubMed]
203. He X, Shan X, Gao X. Identification of a novel HLA-B allele, B*4060 in a Chinese registered bone marrow donor. Tissue Antigens. 2008 in press.
204. Yan LX, Zhu FM, Lv QF, Zhang W. Identification of a novel HLA-B*4061 allele in the Chinese population. Tissue Antigens. 2005;66:705–6. [PubMed]
205. Bernardo I, Castillo-Rama M, Paz-Artal E, Grande C, Castro-Panete MJ. A new HLA-B allele, HLA-B*4068, identified in an Equatorian individual. Tissue Antigens. 2006;68:528–30. [PubMed]
206. Li J, Lazaro AM, Xiao Y, Ng J, Hurley CK. Identification of two new HLA-B alleles, HLA-B*4069 and B*5409, in the Liaoning province of China. Tissue Antigens. 2007;70:345–6. [PubMed]
207. Jin WM, Du D, Liu X, Kong FH, Cai JP. Identification of a novel HLA-B allele HLA-B*4070 in a Chinese donor. Tissue Antigens. 2007;69:618–9. [PubMed]
208. Park J, Kwon OJ, Hong SA, Kwon SY, Cho NS. Identification of a novel HLA-B*40 allele, HLA-B*4071, by sequence-based typing. Tissue Antigens. 2007;70:170–1. [PubMed]
209. Kwon OJ, Kim J, Dirisala VR, Xiao R, Park C. A new HLA-B*40 variant, B*4073, identified by sequence-based typing in the Korean population. Tissue Antigens. 2008;71:250–1. [PubMed]
210. Wang D, Zhang Z. Characterization of the novel allele HLA-B*4075. Tissue Antigens. 2008;71:251–2. [PubMed]
211. Li SY, Xie JH, Dong L, Yan LN, Yuan YH. Identification of the novel allele HLA-B*4076 by sequence-based typing in a Chinese individual. Tissue Antigens. 2009;73:68–9. [PubMed]
212. Sanchez-Gordo F, Balas A, Garcia-Sanchez F, Prat I, Vicario JL. Description of a new HLA-B allele: HLA-B*4077. Tissue Antigens. 2007;70:343–4. [PubMed]
213. Zou HY, Li Z, Cheng LH, Wang DM, Deng ZH. Identification of a new HLA-B*40 allele, HLA-B*4081, in a Chinese individual. Tissue Antigens. 2009;73:70–2. [PubMed]
214. Lee KW. A novel HLA-B*40 allele, HLA-B*4083, identified in a Korean individual. Tissue Antigens. 2008;71:571–2. [PubMed]
215. Han SH, Heo YA, Kwon OJ, Lee A, Lee KR. A new HLA-B*40 allele, HLA-B*4085, identified by sequence-based typing in the Korean population. Tissue Antigens. 2008;72:179–80. [PubMed]
216. Zhu C, Zhang Y, Nie X, He W, Fang Y, Liu Y. A novel HLA-B*40 allele, B*4086, was identified by sequence-based typing in a Chinese donor. Tissue Antigens. 2008;72:181–2. [PubMed]
217. Yan L, Zhu FM, Zhang W, He L. HLA-B*4088, a new allele was identified by polymerase chain reaction sequence-based typing in a Chinese cord blood donor. Tissue Antigens. 2009 in press. [PubMed]
218. Aggarwal R, Stamm L, Zhao W, Fernandez-Vina M, Senitzer D, Berka N. A novel HLA-B allele, B*4093, sharing sequences with B*4006 and B*0702 in an Asian Indian donor. Tissue Antigens. 2008;72:492–4. [PubMed]
219. Zhang Y, Lu HX, Liu Y, Zhu CF. A novel HLA-B allele, B*4096 was identified by sequence-based typing in a Chinese individual. Tissue Antigens. 2009;74:440–2. [PubMed]
220. Eiz-Vesper B, Deluca DS, Blasczyk R, Horn PA. The nature of recombination in HLA-B*4207. Tissue Antigens. 2007;70:164–8. [PubMed]
221. Hoelsch K, Lenggeler I, Knabe H, Hartel K, Klein HG, Woelpl A. Identification of a novel HLA-B*44 variant (B*4441) in three unrelated Caucasian individuals. Tissue Antigens. 2006;67:247–9. [PubMed]
222. Thude H, Hardt C, Schorner U, Ferencik S, Helfricht C, Barz D. Identification of a new HLA-B allele, HLA-B*4443, in a German family. Tissue Antigens. 2005;66:696–9. [PubMed]
223. Ll JP, Li XF, Zhang X, Qu Z, Liu XZ. A novel HLA-B*44 allele, B*4446, identified by sequence-based typing in a Chinese donor. Tissue Antigens. 2006;68:345–6. [PubMed]
224. Ulrich S, Posch U, Helmberg W, Lanzer G. A new HLA-B*44 variant, B*4453, identified by haplotype-specific extraction and sequencing-based typing. Tissue Antigens. 2008;71:91–2. [PubMed]
225. Tijssen HJ, Driessen SW, van Houwelingen KP, Allebes WA, Joosten I. Complete genomic sequence of a novel HLA-B allele, B*4456N. Tissue Antigens. 2009;73:607–9. [PubMed]
226. Hammond L, Dunn PP. A novel HLA-B*44 allele, HLA-B*4459, identified in a renal patient with aberrant B44 serology and characterized by sequence-based typing. Tissue Antigens. 2008;72:494–5. [PubMed]
227. Redman H, Marcus N, Marlowe M, Endres RO. A novel HLA-B*44 allele, B*4466, discovered in a potential donor for a hematopoietic stem cell transplant. Tissue Antigens. 2009;74:347–8. [PubMed]
228. Chu CC, Lee HL, Lin M. Identification of a novel HLA-B allele, B*460102, in three Taiwanese individuals. Tissue Antigens. 2009;73:374–5. [PubMed]
229. Yan LX, Zhu FM, Lv QF, Zhang W. Identification of a novel HLA-B*4608 allele in the Chinese population. Tissue Antigens. 2006;67:253–4. [PubMed]
230. Zhang KL, Li JP, Zhang X, Chen Y, Liu XZ. A novel HLA-B*46 allele, B*4609, identified by sequence-based typing in a Chinese donor. Tissue Antigens. 2007;70:344–5. [PubMed]
231. Yan LX, Zhu FM, Zhang W, He J. Characterization of three novel HLA alleles, HLA-B*4613, HLA-B*4614 and HLA-B*4618, in Chinese individuals. Tissue Antigens. 2009;73:609–11. [PubMed]
232. Sohn YH, Oh HB, Heo YS, Kwon OJ. Structural aspects of B*4617 molecule, a novel HLA-B*46 allele identified by sequence-based typing. Tissue Antigens. 2009;73:72–4. [PubMed]
233. Gao S, Deng ZH, Xu YP. Charaterization of the novel HLA-B allele, B*4621 in a Chinese individual. Tissue Antigens. 2009. in press. [PubMed]
234. Chen MJ, Chu CC, Shyr MH, Lin PY, Yang KL. Discovery of HLA-B*480102 in Taiwanese. Int J Immunogenet. 2008;35:15–8. [PubMed]
235. Kwon OJ, Hwang SH, Heo YS, Hur SS, Oh HB. Structural aspect of B*4811 molecule, a novel HLA-B*48 allele identified by sequence-based typing. Tissue Antigens. 2005;66:707–9. [PubMed]
236. Liu ML, Qi J, Liu S, Zhang Y, Wei XQ. Identification of a novel HLA-B*4814 allele in a Chinese registrant. Tissue Antigens. 2006;67:342–3. [PubMed]
237. Nesci S, Buffi O, Iliescu A, Scalari P, Luchetti MM. HLA-B*4904, a new allele identified in two unrelated individuals from the same Italian region. Tissue Antigens. 2006;68:89–90. [PubMed]
238. Andreini E, Longhi E, Frison S, Bontempelli M, Castellani L, Poli F. Identification of HLA-B*4905 in a Caucasian family. Tissue Antigens. 2006;67:174–6. [PubMed]
239. Balas A, Garcia-Sanchez F, Vicario JL. HLA-B*4907 and B*490101 differs by residue 163 placed in a dominant serologic epitope. Tissue Antigens. 2009 [PubMed]
240. Zhu FM, He J, Zhang W, Yan LX. Identification of a novel HLA-B*510203 allele in a Chinese individual. Tissue Antigens. 2008;71:572–3. [PubMed]
241. Kim KW, Kwon OJ, Kwon SY, Cho NS, Oh DJ. A new HLA-B*5124 variant, B*512402 allele, identified by sequence-based typing. Tissue Antigens. 2009;74:253–4. [PubMed]
242. Endres RO, Redman H, Scavello GS. A novel HLA-B*51 allele, HLA-B*5149. Tissue Antigens. 2007;70:259–60. [PubMed]
243. Roh EY, Shin S, Yoon JH, Ahn BM, Chang JY. A new HLA-B*51 variant, B*5158, identified by sequence-based typing in a Korean individual. Tissue Antigens. 2009;73:375–6. [PubMed]
244. Xiao L, Luo M, Zhu H. Identification of a novel HLA-B*51 variant allele, B*5159 in a Chinese Han individual. Tissue Antigens. 2009 in press.
245. Chen MJ, Chu CC, Shyr MH, Lin CL, Lin PY, Yang KL. A novel HLA-B allele, B*5214, detected in a Taiwanese volunteer bone marrow donor using a sequence-based typing method. Int J Immunogenet. 2009. in press. [PubMed]
246. Heinold A, Bauer M, Scherer S, Opelz G, Tran TH. Characterization of a new HLA-B allele, HLA-B*5312, and re-evaluation of the published sequences of the untranslated regions of HLA-B*35 and HLA-B*53. Tissue Antigens. 2007;70:319–23. [PubMed]
247. Cheng LH, Zhu WG, Lan YX, Zou HY, Li Z, Jin SZ. A novel HLA-B*54 allele, B*5417, identified in a Northern Chinese Han individual. Tissue Antigens. 2009;74:442–4. [PubMed]
248. Yan LX, Zhu FM, Lv QF. Sequence analysis of the novel allele HLA-B*5408 N in the Chinese population. Tissue Antigens. 2006;68:182. [PubMed]
249. Chu CC, Lee KC, Lee HL, Lin M. Identification of HLA-B*5410 in Taiwan. Tissue Antigens. 2009;73:611–2. [PubMed]
250. Yan LN, Li SY, Dong Z, et al. Identification of a novel HLA-B*54 allele, B*5411, by sequence-based typing in a Chinese individual. Tissue Antigens. 2008;71:484–5. [PubMed]
251. Lee KW, Seo JJ. A novel HLA-B allele: HLA-B*5419. Tissue Antigens. 2009;74:444–5. [PubMed]
252. Hammond L, Street J, Downing J, Pepperall J, Darke C. A new HLA-B*5501 variant–B*550104. Tissue Antigens. 2006;68:182–3. [PubMed]
253. Yan LX, Zhu FM, Zhang W, He J. A novel allele HLA-B*550203 was identified by polymerase chain reaction-sequence-based typing. Tissue Antigens. 2009;74:254–5. [PubMed]
254. Witter K, Volgger A, Zahn R, Scholz S, Sala M, Albert ED. Bone marrow donor routine HLA typing identified a novel B*55 allele, B*5517, confirmed by allele-specific DNA cycle sequencing. Tissue Antigens. 2005;66:58–60. [PubMed]
255. Lebedeva TV, Huang A, Ohashi M, et al. The recombinant HLA-B*5518 allele supports the evidence of conserved haplotype association of rare alleles. Tissue Antigens. 2005;66:156–9. [PubMed]
256. Jeong SM, Lee MN, Park SY, Kwon OJ, Nah SY. Identification of a new HLA-B*55 allele, HLA-B*5519, in the Korean population. Tissue Antigens. 2006;68:183–5. [PubMed]
257. Yan LX, Zhu FM, Zhang W. Sequence analysis of the novel allele HLA-B*5522 in the Chinese population. Tissue Antigens. 2007;69:202–3. [PubMed]
258. Emmerich F, Schonemann C, Galicki L, Salama A. Identification of a novel HLA-B allele, HLA-B*5529, by haplotype-specific sequencing. Tissue Antigens. 2008;71:486. [PubMed]
259. Yan LX, Zhu FM, Zhang W, He J. HLA-B*5530, a new allele was identified by sequence-based typing in a Chinese individual. Tissue Antigens. 2008 in press. [PubMed]
260. Zhuang Y, Song YH, Zhang Y, Nie XM, Zhu CF. A novel HLA-B allele, B*5535, was identified by sequence-based typing in a Chinese individual. Tissue Antigens. 2009 in press. [PubMed]
261. Rahal M, Kervaire B, Villard J, Tiercy JM. DNA typing by microbead arrays and PCR-SSP: apparent false-negative or -positive hybridization or amplification signals disclose new HLA-B and -DRB1 alleles. Tissue Antigens. 2008;71:238–41. [PubMed]
262. Altermann WW, Grondkowski V, Reichert S, Seliger B, Schlaf G. A novel HLA-B*57 (B*5714) allele in a healthy male Caucasian individual. Tissue Antigens. 2008;71:253–4. [PubMed]
263. Figueiredo C, Mbulaiteye S, Ndugwa CM, Schulz T, Eiz-Vesper B. Assessment of the amino acid substitution in HLA-B*5719 for allorecognition. Tissue Antigens. 2009;73:376–8. [PMC free article] [PubMed]
264. Zhu FM, Zhang W, He J, Yan LX. Identification of the novel allele HLA-B*580102 by sequence-based typing in a Chinese individual. Tissue Antigens. 2009;73:74–5. [PubMed]
265. Yoon S, Baek JY, Hur SS, Kwon OJ, Kwack K. Identification of a novel HLA-B*58 allele, B*5813, by sequence-based typing of DNA from Korean baby cord blood. Tissue Antigens. 2007;69:366–7. [PubMed]
266. Ueta M, Matsushita M, Sotozono C, Kinoshita S, Tokunaga K. Identification of a novel HLA-B allele, HLA-B*5904. Tissue Antigens. 2009;73:612–4. [PubMed]
267. Xu Y, Yang B, Zeng J, Wang D, Deng Z. Characterization of the genomic full-length sequence of HLA-Cw*0706 in two Chinese individuals. Tissue Antigens. 2009 in press.
268. Lebedeva TV, Ohashi M, Mastromarino SA, Alosco SM, Yu N. New HLA-C alleles identified in minority populations. Tissue Antigens. 2007;70:441–2. [PubMed]
269. Xu Y, Yang B, Gao S, Deng Z, Xie Z. Genomic full length sequence of HLA-Cw*0103 and Cw*0107, identified by cloning and sequencing. Tissue Antigens. 2009 in press. [PubMed]
270. Kwon OJ, Hwang SH, Hur SS, Oh HB. Novel HLA-Cw*01 allele, Cw*0111, identified by sequence-based typing. Tissue Antigens. 2005;66:706–7. [PubMed]
271. Lazaro AM, Xiao Y, Cao K, et al. Twenty-three novel alleles increase diversity at the HLA-C locus. Tissue Antigens. 2008;71:560–3. [PubMed]
272. Ding L, Lin WZ, Wu YP, Chen SW, Xu AL. A novel HLA-C allele, Cw*0119, isolated from the Han Chinese. Tissue Antigens. 2007;70:346–8. [PubMed]
273. Li Z, Zhang H, Jin SZ. Identification of a new HLA-Cw*01 variant, Cw*0121, by sequence-based typing in a Chinese patient. Tissue Antigens. 2009;74:449–51. [PubMed]
274. Jin SZ, Zhu WG, Lan YX, Zou HY, Cheng LH. A novel HLA-Cw*0124 allele found in a Chinese Han patient from southern China. Tissue Antigens. 2009 in press. [PubMed]
275. Deng ZH, Wang DM. A novel HLA-Cw*01 variant allele, HLA-Cw*0130. Tissue Antigens. 2009 [PubMed]
276. Elamin NE, Elbashir MI, Elkhidir IM, Elghazali G, Blasczyk R, Horn PA. Identification of four new HLA-Cw alleles in the Sudanese population. Tissue Antigens. 2007;69:270–2. [PubMed]
277. Serov Y, Hommel-Berrey G, Lobashevsky A. Identification of a novel HLA-C allele, Cw*021602, by sequence-based typing in a family of German descent. Tissue Antigens. 2009;74:349–50. [PubMed]
278. Minevich G, Kuhn L, Polistena C, Nuara J, Winchester R. Description of two new HLA-C alleles in a black South African population. Tissue Antigens. 2008;71:72–6. [PMC free article] [PubMed]
279. Balas A, Bustamante L, Garcia-Sanchez F, Vicario JL. The new HLA-C allele, Cw*0220, shows a new polymorphism at amino acid position 169. Tissue Antigens. 2008;71:93. [PubMed]
280. Johnson J, Street J, Hammond L, Iley C, Darke C. Two new HLA-C alleles: Cw*0222 and Cw*0434. Tissue Antigens. 2009;73:76–8. [PubMed]
281. Xu YP, Deng ZH, Wang DM, Zeng JQ, Jing SZ. Genomic full-length sequence of HLA-Cw*140201, identified by cloning and sequencing. Tissue Antigens. 2009 in press. [PubMed]
282. Xu Y, Deng Z, Zeng J, Gao S, Yang B. Genomic full length sequence of HLA-Cw*030301, identified by cloning and sequencing. Tissue Antigens. 2009;74:452–3. [PubMed]
283. Pang SW, Chan SH, Ren EC. Identification of two novel HLA-C alleles, HLA-Cw*1217 and HLA-Cw*030404, in Singapore Chinese. Tissue Antigens. 2006;67:177–9. [PubMed]
284. Hammond L, Street J, Johnson J, Pepperall J, Darke C. A new HLA-Cw*03 variant - Cw*031102. Tissue Antigens. 2006;68:455–6. [PubMed]
285. Middleton D, Meenagh A, Marsh SGE, Martin J. A HLA-Cw*03 allele, Cw*0322Q with limited or no expression. Tissue Antigens. 2006;67:343–5. [PubMed]
286. Nesci S, Malagoli A, Iliescu A, Buffi O, Carella G. Characterization of the novel allele HLA-Cw*0331 by sequence-based typing. Tissue Antigens. 2007;69:203–4. [PubMed]
287. Kim MH, Oh HB, Kwon OJ. A novel HLA-Cw*03 allele, Cw*033802, identified by sequence-based typing. Tissue Antigens. 2007;70:522–4. [PubMed]
288. Cheng LH, Li Z, Jin SZ, Zou HY. Sequence-based typing characterization of the novel HLA-Cw*0340 allele in a Chinese individual. Tissue Antigens. 2008;72:495–7. [PubMed]
289. Endres RO, Redman H, Baumbach A, Capper J. A novel HLA-C locus allele with codon 54 deletion, Cw*0346. Tissue Antigens. 2007;70:524–5. [PubMed]
290. Zou HY, Li Z, Deng ZH. Characterization of a new HLA-C allele in a Chinese family by sequence-based typing: HLA-Cw*0348. Tissue Antigens. 2009;73:616–8. [PubMed]
291. Lee KW, Jung YA, Eom HS. Description of a novel HLA-Cw*03 allele, HLA-Cw*0349, identified in a Korean individual. Tissue Antigens. 2008;72:407–9. [PubMed]
292. Cheng LH, Jin SZ, Zhu WG, Lan YX, Li Z. Full length sequence of the HLA-Cw*0361 allele identified in a Chinese Han potential bone marrow donor from Northern China. Tissue Antigens. 2009 in press. [PubMed]
293. Elsner HA, Blasczyk R. The phylogenies of introns 4–7 demonstrate an inconsistent pattern between human leukocyte antigen-C group topologies. Tissue Antigens. 2004;63:109–21. [PubMed]
294. Xu Y, Deng Z, Zeng J, Gao S, Wang D. A novel HLA-Cw*04 allele, Cw*04010103, identified by genomic full length cloning and sequencing. Tissue Antigens. 2009;74:453–5. [PubMed]
295. Deng ZH, Yang BC, Zhou HY, Wang DM, Chen SW, Xu AL. Characterization and sequence analysis of the novel HLA-Cw*040105 allele in a Chinese Uygur individual. Tissue Antigens. 2008;72:182–4. [PubMed]
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