PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of neurologyNeurologyAmerican Academy of Neurology
 
Neurology. 2009 September 15; 73(11): 903.
PMCID: PMC2848583

The imaging spectrum of neuro-Behçet disease

S Taylor, MSc, MD, O Islam, MD, FRCPC, M Joneja, MD, MEd, FRCPC, M Melanson, MD, FRCPC, and A Y. Jin, PhD, MD, FRCPC

An 18-year-old man with recurrent oral and genital ulcers presented with uveitis, encephalopathy, headache, spastic paraparesis, and urinary retention. MRI demonstrated periventricular and hypothalamic lesions, sinus thrombosis, and longitudinally extensive spinal cord lesions (figure). Treatment with high-dose steroid medication resulted in dramatic neurologic and radiographic improvement.

figure znl0350969090001
Figure Imaging features of neuro-Behçet disease

Behçet disease is a multisystemic inflammatory disease characterized by recurrent oral aphthae, uveitis, and genital ulcers. Two patterns of CNS involvement have been described, including direct parenchymal involvement and cerebrovascular involvement.1 Simultaneous symptomatic parenchymal, vascular, and spinal cord lesions characteristic of neuro-Behçet disease in a single patient are highly unusual.

Notes

Disclosure: The authors report no disclosures.

Address correspondence and reprint requests to Dr. Albert Y. Jin, Department of Medicine (Neurology), Queen’s University c/o Connell 7, Division of Neurology, Kingston General Hospital, Kingston, Ontario, Canada K7L 2V7; ac.usneeuq@jya

&NA;

1. Al-Araji A, Kidd DP. Neuro-Behcet’s disease: epidemiology, clinical characteristics, and management. Lancet Neurol 2009;8:192–204. [PubMed]

Articles from Neurology are provided here courtesy of American Academy of Neurology