Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes
1 MRC Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
2 NIHR Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, Kings College, London, UK.
3 Department of Neuroscience, Institute of Psychiatry, Kings College, London, UK.
4 Institute of Public Health, University of Cambridge, Cambridge, UK.
5 Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
6 Mercer's Institute for Research on Aging, St. James Hospital and Trinity College, Dublin, Ireland.
7 Institute of Genetics, Queen's Medical Centre, University of Nottingham, NG7 2UH, UK.
8 Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, UK.
9 Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.
10 Clinical Neuroscience Research Group, Greater Manchester Neurosciences Centre, University of Manchester, Salford, UK.
11 Oxford Project to Investigate Memory and Ageing (OPTIMA), University of Oxford, Level 4, John Radcliffe Hospital, Oxford OX3 9DU, UK.
12 Dementia Research Group, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK.
13 Department of Molecular Neuroscience and Reta Lilla Weston Laboratories, Institute of Neurology, London, UK.
14 MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
15 Dementia Research Centre, Department of Neurodegenerative Diseases, University College London, Institute of Neurology, London, UK.
16 Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105 Bonn, Germany.
17 Institute of Primary Medical Care, University Medical Center Hamburg-Eppendorf, Germany.
18 Department of Psychiatry, Charité Berlin, Germany.
19 Department of Psychiatry and Psychotherapy, University of Erlangen-Nüremberg, Germany.
20 LVR-Hospital Essen, Department of Psychiatry and Psychotherapy, University Duisburg-Essen, Germany.
21 Institute for Stroke and Dementia Reserach, Klinikum der Universität München, Marchioninistr. 15, 81377, Munich, Germany.
22 Department of Neurology, Klinikum der Universität München, Marchioninistr. 15, 81377, Munich, Germany.
23 Department of Geriatric Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, D-68161 Mannheim, Germany.
24 Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Laboratory of Neuroimaging & Biomarker Research, Trinity College, University of Dublin, Ireland.
25 Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig-Maximilian University, Munich, Germany.
26 Centre for Geriatric Medicine and Section of Gerontopsychiatry and Neuropsychology, Medical School, University of Freiburg, Germany.
27 Departments of Psychiatry, Neurology and Genetics, Washington University School of Medicine, St Louis, MO 63110, US.
28 Department of Biology, Brigham Young University, Provo, UT, 84602, USA.
29 Neurodegenerative Brain Diseases group, Department of Molecular Genetics, VIB, Antwerpen, Belgium.
30 Institute Born-Bunge and University of Antwerp; Antwerpen, Belgium.
31 Memory Clinic and Department of Neurology, ZNA Middelheim, Antwerpen, Belgium.
32 Department of Mental Health Sciences, University College London, UK.
33 The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
34 MRC Centre for Neurodegeneration Research, Department of Clinical Neuroscience, King's College London, Institute of Psychiatry, London, SE5 8AF, UK.
35 3rd Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
36 Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, USA.
37 Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, D-53127 Bonn, Germany.
38 Institute of Human Genetics, University of Bonn, Wilhelmstr. 31, D-53111 Bonn, Germany.
39 Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Hufelandstr. 55, D-45147 Essen, Germany.
40 Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.
41 Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.
42 Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida 32224, USA.
43 Division of Biomedical Statistics and Informatics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.