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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
Am J Addict. Author manuscript; available in PMC 2010 March 25.
Published in final edited form as:
PMCID: PMC2845168

Treatment Challenges Associated with Comorbid Substance Use and Posttraumatic Stress Disorder: Clinicians’ Perspectives


A significant proportion of individuals with substance use disorders (SUDs) meet criteria for comorbid posttraumatic stress disorder (PTSD). This comorbidity confers a more complicated clinical presentation that carries with it formidable treatment challenges for practitioners. The current study examined sources of difficulty and gratification among clinicians (N = 423) from four national organizations who completed an anonymous questionnaire. As expected, the findings revealed that comorbid SUD/PTSD was rated as significantly more difficult to treat than either disorder alone. The most common challenges associated with treating SUD/PTSD patients included knowing how to best prioritize and integrate treatment components, patient self-destructiveness and severe symptomatology, and helping patients abstain from substance use. The findings increase understanding of SUD/PTSD treatment challenges, and may be useful for enhancing therapist training programs, supervision effectiveness, and designing optimal SUD/PTSD interventions.


Epidemiologic surveys demonstrate substantial comorbidity of substance use disorders (SUDs) and other psychiatric conditions.14 Recent data from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), which surveyed more than 43,000 adults in the United States, found that 40.9% of individuals with an SUD had a comorbid lifetime mood disorder and 29.9% had a comorbid lifetime anxiety disorder.5 A frequently co-occurring anxiety disorder is posttraumatic stress disorder (PTSD).6,7 The comorbidity of SUDs and PTSD results in a more complicated clinical presentation and treatment prognosis, including higher rates of Axis I and II disorders, higher relapse rates, more medical and interpersonal problems, and poorer aftercare attendance.817

Not surprisingly, patients with comorbid SUDs and PTSD present a formidable challenge to even the most seasoned clinicians and consensus regarding ideal treatment practices for SUD/PTSD patients is lacking. Contrary to many patients’ treatment preferences,1821 the majority of SUD/PTSD patients receive SUD treatment only.21,22 Exposure-based therapies, which are the gold standard in treatment for PTSD, are underutilized by clinicians.23 Reasons for this are varied, and include a concern that exposure-based therapies will induce relapse or clinical deterioration.2325 However, the few studies that have investigated the tolerability and efficacy of addressing PTSD among individuals with SUDs do not indicate any increased risk of use or relapse, but rather demonstrate significant reductions in craving and substance use.2630

Little research has been conducted to date on clinicians’ perspectives of working with this dually diagnosed population. In one study of 147 clinicians attending professional workshops for Seeking Safety, an integrated SUD/PTSD treatment, Najavits31 found that individuals with co-occurring disorders were perceived by clinicians as more difficult to work with as compared to individuals with either disorder alone. In addition, certain clinician and work setting characteristics were associated with greater difficulty in treating SUD/PTSD patients. For example, clinicians without a personal history of trauma or SUD, Ph.D.-level clinicians, and those working primarily in a mental health setting reported the greatest difficulty in working with SUD/PTSD patients.31

The goal of the current study was to build on previous work investigating clinicians’ perspectives of treating SUD/PTSD patients, with a particular emphasis on areas of difficulty. Specifically, quantitative and qualitative information was gathered regarding common treatment challenges and dilemmas associated with treating SUD/PTSD patients. Such information is critical for improving therapist training programs and enhancing SUD/PTSD interventions.


Participants were 423 clinicians who completed the Clinician Survey on PTSD and Substance Abuse.31 An invitation to participate in the study was sent to four national organizations via their member listservs: the College on Problems of Drug Dependence, Association for Behavioral and Cognitive Therapies, International Society for Traumatic Stress Studies, and the National Institute on Drug Abuse’s Clinical Trials Network. Clinicians were invited to participate in a brief, anonymous, online survey regarding their views of treating patients with alcohol or drug use disorders and comorbid PTSD. Participants did not receive compensation.

The Clinician Survey on PTSD and Substance Abuse31 is a 40-item questionnaire that inquires about how gratifying and difficult it is to work with patients with SUDs, PTSD, or both; what areas are most difficult in treating this dual diagnosis; and common emotions clinicians experience when working with SUD/PTSD patients. The survey also collects, for example, demographic data; years and type of training (eg, social worker, doctoral-level psychologist, psychiatrist, certified alcohol/drug counselor); primary work setting (eg, mental health, substance abuse, dual diagnosis program); and theoretical orientation.

Descriptive analyses were conducted for questionnaire items of interest. Independent samples t-tests, analyses of variance (ANOVAs) and bivariate correlations were used to test associations between variables of interest. Alpha was set at .05 for all analyses.



Table 1 presents the demographic and descriptive characteristics of respondents. The average number of years of clinical experience was 14.4 years among professionals and 3.9 years (SD = 2.1) among clinicians still in training. As can be seen, training backgrounds and work settings were diverse.

Respondent demographics (N = 423)

SUD/PTSD Treatment Challenges

Table 2 presents the mean responses to items assessing difficulties associated with treating SUD/PTSD patients. As can be seen, respondents rated the treatment of the dual diagnosis as the most difficult, followed by SUDs alone, then PTSD alone (F (2, 750) = 101.10, p < .001). The most difficult aspects of treating SUD/PTSD patients included self-destructive behaviors (eg, suicidal ideation, cutting), heavy case management needs (eg, finding services, referrals), and patients’ dependency (eg, needing high levels of care).

SUD/PTSD treatment challenges


Clinicians were also asked to report in an open-ended fashion about common dilemmas in treating SUD/PTSD patients. Examples describing the three most commonly reported areas of difficulty are found in Table 3. Approximately15% of the sample reported struggling with treatment integration or implementation issues and 13% reported struggling with patients’ severe symptomatology and self-destructive behaviors. Some clinicians (7.8%) endorsed the challenge of helping patients abstain from alcohol or drug use during treatment.

Common SUD/PTSD treatment dilemmas: Quotes from clinicians

A minority of clinicians reported a lack of appropriate supervision or training (3.8%). This often involved clinicians reporting that they had training in one area (eg, PTSD), but did not feel competent to treat the comorbid conditions (eg, SUDs), and hence would refer the patient out. Several clinicians also reported that the treatment setting that they practiced in did not support integrated treatment (3.5%), and 2.6% of the sample reported a concern that patients’ substance use would escalate due to addressing the PTSD.


The most commonly reported emotions associated with treating SUD/PTSD patients were frustration and anger (22.9%). Clinicians reported experiencing these emotions as a result of patients’ self-destructive behaviors, substance use, missed appointments, lack of insight, or poor judgment. In addition, clinicians reported experiencing anger toward the patient’s perpetrator and because of the slow progress of therapy. Sadness was the second most commonly reported emotion (10.6%) in clinical work with SUD/PTSD patients.

SUD/PTSD Treatment Sources of Gratification

Sources of gratification, which could be useful targets of emphasis during supervision or therapist training, were also examined (see Table 4). Significant differences by diagnostic group were observed, F (2, 704) = 24.80, p < .001. Treating PTSD alone was rated as the most gratifying, followed by the dual diagnosis, then SUDs alone (p < .001). Common sources of gratification included developing expertise in working with this patient population, teaching patients new coping skills, and helping patients become abstinent from alcohol and drugs.

SUD/PTSD Sources of Treatment Gratification

Clinicians uniformly responded with more gratification than difficulty in treating patients with SUDs alone [M = 2.24 vs. 1.04, t(378) = −14.82, p < .001]; PSTD alone [M = 2.51 vs. .89, t(369) = −24.95, p < .001]; and with the dual diagnosis [M = 2.38 vs. 1.51, t(370) = −12.72, p < .001]. Correlations between ratings of difficulty and gratification indicated inverse relationships for each diagnostic group (p < .001). As the perceived difficulty of treating patients increased, the gratification decreased.


This study investigated challenges involved in treating patients with SUDs, PTSD, or co-occurring SUD/PTSD. Clinicians (N = 423) from varying training backgrounds and treatment settings participated. The findings underscore how challenging and intense SUD/PTSD clinical work can be, even for experienced clinicians (the average number of years of clinical experiences was 14.4 years).

Consistent with previous research,31 clinicians rated comorbid SUD/PTSD as the most difficult group to treat. One of the most unique and challenging issues for therapists in treating SUD/PTSD is understanding when and how to best integrate the different treatment components for trauma and SUDs. Typically, SUD/PTSD patients who present for treatment are still actively using substances or in early remission. Many SUD/PTSD patients will relapse at some point during treatment, whether enrolled in an integrated or standard substance use treatment program. How much “clean time,” therefore, is needed before working on the trauma? When is the optimal time to introduce trauma/PTSD work? Should trauma work be discontinued if the patient relapses? Can patients who significantly decrease but still continue to use substances still benefit from trauma work? Clearly, these are important questions that need to be addressed in future research so that treatment guidelines may be established.

Although inconclusive at this point, the extant literature does provide some information to help address these concerns and guide clinical efforts. First, many of the empirically investigated integrated SUD/PTSD treatments strongly encourage, but do not require, abstinence from substance use before beginning trauma work.27, 33 These treatments have been shown to result in significant improvements in both SUD and PTSD symptoms, demonstrating that abstinence is not absolutely essential before patients can benefit from concurrent trauma work. Indeed, addressing the trauma may help facilitate reduction in substance use for patients who are continuing to use in order to cope with trauma-related symptoms.

Regarding the ideal time in treatment to initiate trauma work, integrated treatments generally introduce trauma work following an initial phase focused on substance use. During the initial phase, which may last from one to three months,17,31,32 patients are taught coping skills (eg, drug refusal skills, coping with triggers, problem solving, relaxation training) to help achieve or maintain abstinence or significantly reduce alcohol and drug intake. Patients receive psychoeducation beginning at the very first session, however, about the interrelationship between PTSD and SUDs. Indications that a SUD/PTSD patient is prepared to engage in trauma work (eg, prolonged exposure) include, for example, significant reductions in substance use, significant reductions in or absence of self-harming behaviors or suicidal ideation, a solid understanding of the rationale for trauma work and what it will involve, adequate learning and adoption of healthy coping skills, a collaborative patient-therapist agreement to begin trauma work, and realistic expectations regarding the potential initial difficulties of engaging in trauma work and the importance of sticking with it by using healthy coping skills.32,34,35 In summary, some length (eg, one to three months) of abstinence or significantly reduced substance use is encouraged before beginning trauma work, although it remains unclear exactly how much time is necessary for trauma work to be beneficial.

The findings from this study identify severe symptomatology and self-destructive behaviors as another common challenge of treating SUD/PTSD patients. In the event of a crisis, the decision to move forward with trauma work in would depend on several factors (eg, successful resolution of the crisis, extent of the crisis, patient’s willingness). Because avoidance is strongly characteristic of both PTSD and substance abuse, clinicians working with SUD/PTSD patients need to consider whether a patient might be attempting to avoid discussing the trauma through such a crisis. As indicated earlier, many patients relapse during treatment. A lapse does not necessarily represent a crisis and does not always require a delay in trauma work. In fact, it may not be beneficial (from an avoidance perspective) to defer trauma work when a patient lapses. Rather, relapse prevention skills should be reviewed, the difference between a lapse and a full-blown relapse emphasized to protect against the abstinence violation effect, and a functional analysis performed to help identify antecedents of the use.

Supervision of SUD/PTSD clinicians can be improved by addressing these common challenges and by helping clinicians to build the necessary skills and expertise. Given the common challenges associated with severe symptomatology and self-destructiveness, it is important for supervisors to instruct and review with SUD/PTSD therapists their crisis intervention skills, distress tolerance techniques, anger management and disarming techniques, negative affect management, and ways to handle patient dissociation. Because of the extensive case management needs that many SUD/PTSD patients have, therapists and supervisors should have available a list of local services in the community (eg, housing, vocational rehabilitation, domestic violence shelters) that patients can access. This will help take some of the burden off the clinician.

Supervisors can also assist by helping clinicians balance the more challenging aspects of treating SUD/PTSD patients with the sources of gratification. This may help prevent or reduce therapist burn out. The top three sources of gratification in working with SUD/PTSD patients were developing expertise in working with these clients, teaching clients new coping skills, and helping clients become abstinent from substances. Surveys such as the one used in this study can be modified and used by supervisors to assess challenges and sources of gratification among SUD/PTSD their supervisees, and then tailor supervision efforts and goals accordingly.


While this study was anonymous, the findings are based on self report and, as such, biases may exist. Clinicians from four national organizations were invited to participate. As such, the findings may not generalize well to clinicians outside of those organizations. Data on treatment outcome was not collected in this study; thus, it is unclear how clinicians’ perspectives impact treatment outcome. A strength of the study is the large sample of clinicians who participated with diverse training backgrounds, work settings, and theoretical orientations.


The findings underscore the significant challenges that exist on multiple levels in treating comorbid SUDs and PTSD. One of the most common and unique challenges associated with treating SUD/PTSD patients involves knowing how to best integrate treatment components for PTSD and SUD symptoms. Clinicians frequently struggle with questions regarding when to initiate or defer trauma work and how to deal with continued patient substance use. While more research is clearly needed to help conclusively answer these questions, the extant literature provides some tentative guidance and supports the use of integrated psychosocial therapies that address both SUDs and PTSD concurrently. The findings from this study help increase understanding of the issues involved in providing treatment to SUD/PTSD patients, and may be helpful in improving therapist training programs, supervision practices, and the design of integrated treatment manuals for comorbid SUDs and PTSD.


We wish to thank the following organizations for their assistance with data collection: the College on Problems of Drug Dependence, Association for Behavioral and Cognitive Therapies, International Society for Traumatic Stress Studies, and the National Institute on Drug Abuse’s Clinical Trials Network. In addition, we thank the clinicians who participated in the study, Ms. Royce Sampson for her assistance with data collection, Dr. Thomas McLellan for his feedback, and Dr. Lisa Najavits for permitting the use of her questionnaire.


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