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Cover photograph (Copyright © 2010, American Society for Microbiology. All Rights Reserved.): Crystal structure of the Pseudomonas aeruginosa epoxide hydrolase virulence factor Cif. The structure is shown as a ribbon diagram, colored by temperature factor (blue = low; green = intermediate) and as a transparent molecular surface (gray). Protein crystals are seen in the background. The crystal structure identifies the key active-site residues, represented as sticks colored by atom type (green = carbon, blue = nitrogen, red = oxygen). The structure shows how novel epoxide hydrolase active-site motifs are stereochemically accommodated and provides a road map for structure-function analysis of this novel class of virulence factors. (See related article on page 1785.)

J Bacteriol. 2010 April; 192(7): Cover