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Coefficients of gene expression variation (CV), defined as standard deviation normalised to expression mean, vary for CORUM and non-CORUM genes.
A) Effects of resolution and dynamic range of expression arrays on CVs. The measurable variation in gene expression is limited by the sensitivity of the employed array technology. Genes which are expressed at extremely low levels, or not expressed at all, cluster in the low expression/low CV region. Shown in grey are genes which were excluded from further calculations (standard deviation ). B) CORUM genes have significantly smaller CVs than non-CORUM genes. Outliers beyond are not shown. C) Large CORUM complexes exhibit lower average CVs of their members.