1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4. Washington, DC: American Psychiatric Association; 1994.
2. World Health Organization. International Classification of Diseases. 10. Geneva: World Health Organization; 2002.
3. Rice CE, Baio J, Van Naarden BK, Doernberg N, Meaney FJ, Kirby RS. A public health collaboration for the surveillance of autism spectrum disorders. Paediatr Perinat Epidemiol. 2007;21(2):179–190. [PubMed] 4. De Giacomo A, Fombonne E. Parental recognition of developmental abnormalities in autism. Eur Child Adolesc Psychiatry. 1998;7(3):131–136. [PubMed] 5. Rogers SJ, DiLalla DL. Age of symptom onset in young children with pervasive developmental disorders. J Am Acad Child Adolesc Psychiatry. 1990;29(6):863–872. [PubMed] 6. Wimpory DC, Hobson RP, Williams JM, Nash S. Are infants with autism socially engaged? A study of recent retrospective parental reports. J Autism Dev Disord. 2000;30(6):525–536. [PubMed]
7. Coonrod EE, Stone W. Early concerns of parents of children with autistic and nonautistic disorders. Infants Young Child. 2004;17(3):258–268.
8. Yeargin-Allsopp M, Rice C, Karapurkar T, Doernberg N, Boyle C, Murphy C. Prevalence of autism in a US metropolitan area. JAMA. 2003;289(1):49–55. [PubMed] 9. Autism and Developmental Disabilities Monitoring Network Surveillance Year 2002 Principal Investigators; Centers for Disease Control and Prevention. Prevalence of autism spectrum disorders: autism and developmental disabilities monitoring network, 14 sites, United States, 2002. MMWR Surveill Summ. 2007;56(1):12–28. [PubMed] 10. Mandell DS, Listerud J, Levy SE, Pinto-Martin JA. Race differences in the age at diagnosis among Medicaid-eligible children with autism. J Am Acad Child Adolesc Psychiatry. 2002;41(12):1447–1453. [PubMed] 11. Croen LA, Grether JK, Hoogstrate J, Selvin S. The changing prevalence of autism in California. J Autism Dev Disord. 2002;32(3):207–215. [PubMed] 12. Johnson CP, Myers SM. American Academy of Pediatrics, Council on Children With Disabilities. Identification and evaluation of children with autism spectrum disorders. Pediatrics. 2007;120(5):1183–1215. [PubMed] 13. Filipek PA, Accardo PJ, Ashwal S, et al. Practice parameter: screening and diagnosis of autism: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society. Neurology. 2000;55(4):468–479. [PubMed] 14. American Academy of Pediatrics, Council on Children With Disabilities; Section on Developmental Behavioral Pediatrics; Bright Futures Steering Committee; Medical Home Initiatives for Children With Special Needs Project Advisory Committee. Identifying infants and young children with developmental disorders in the medical home: an algorithm for developmental surveillance and screening [published correction appears in Pediatrics. 2006;118(4):1808–1809] Pediatrics. 2006;118(1):405–420. [PubMed] 17. First Signs. Developmental disability, early intervention, developmental delays, autism screening and early intervention autism: first signs. [Accessed March 5, 2009]. Available at: www.firstsigns.org. 18. Palomo R, Belinchon M, Ozonoff S. Autism and family home movies: a comprehensive review. J Dev Behav Pediatr. 2006;27(2 suppl):S59–S68. [PubMed] 19. Werner E, Dawson G. Validation of the phenomenon of autistic regression using home videotapes. Arch Gen Psychiatry. 2005;62(8):889–895. [PubMed] 20. Zwaigenbaum L, Thurm A, Stone W, et al. Studying the emergence of autism spectrum disorders in high-risk infants: methodological and practical issues. J Autism Dev Disord. 2007;37(3):466–480. [PubMed] 21. Young RL, Brewer N, Pattison C. Parental identification of early behavioural abnormalities in children with autistic disorder. Autism. 2003;7(2):125–143. [PubMed] 22. Gray KM, Tonge BJ. Are there early features of autism in infants and preschool children? J Paediatr Child Health. 2001;37(3):221–226. [PubMed]
23. Charman T, Baron-Cohen S, Swettenham J, Baird G, Cox T, Drew A. Testing joint attention, imitation, and play as infancy precursors to language and theory of mind. Cogn Dev. 2000;15(4):481–498.
24. Rutter M, Lord C. Language disorders associated with psychiatric disturbance. In: Yule W, Rutter M, editors. Language Development and Disorders. Philadelphia, PA: JB Lippincott; 1987. pp. 206–233.
25. Luyster R, Richler J, Risi S, et al. Early regression in social communication in autism spectrum disorders: a CPEA study. Dev Neuropsychol. 2005;27(3):311–336. [PubMed] 26. Tuchman RF, Rapin I. Regression in pervasive developmental disorders: seizures and epileptiform electroencephalogram correlates. Pediatrics. 1997;99(4):560–566. [PubMed] 27. Kurita H. Infantile autism with speech loss before the age of thirty months. J Am Acad Child Psychiatry. 1985;24(2):191–196. [PubMed] 28. Hoshino Y, Kaneko M, Yashima Y, Kumashiro H, Volkmar FR, Cohen DJ. Clinical features of autistic children with setback course in their infancy. Jpn J Psychiatry Neurol. 1987;41(2):237–245. [PubMed] 29. Maestro S, Muratori F, Cavallaro MC, et al. Attentional skills during the first 6 months of age in autism spectrum disorder. J Am Acad Child Adolesc Psychiatry. 2002;41(10):1239–1245. [PubMed] 30. Maestro S, Muratori F, Barbieri F, et al. Early behavioral development in autistic children: the first 2 years of life through home movies. Psychopathology. 2001;34(3):147–152. [PubMed] 31. Dawson G, Toth K, Abbott R, et al. Early social attention impairments in autism: social orienting, joint attention, and attention to distress. Dev Psychol. 2004;40(2):271–283. [PubMed] 32. Adrien JL, Faure M, Perrot A, et al. Autism and family home movies: preliminary findings. J Autism Dev Disord. 1991;21(1):43–49. [PubMed] 33. Osterling J, Dawson G. Early recognition of children with autism: a study of first birthday home videotapes. J Autism Dev Disord. 1994;24(3):247–257. [PubMed] 34. Maestro S, Muratori F, Cesari A, et al. Course of autism signs in the first year of life. Psychopathology. 2005;38(1):26–31. [PubMed] 35. Baranek GT. Autism during infancy: a retrospective video analysis of sensory-motor and social behaviors at 9–12 months of age. J Autism Dev Disord. 1999;29(3):213–224. [PubMed] 36. Colgan SE, Lanter E, McComish C, Watson LR, Crais ER, Baranek GT. Analysis of social interaction gestures in infants with autism. Child Neuropsychol. 2006;12(4–5):307–319. [PubMed] 37. Yirmiya N, Gamliel I, Shaked M, Sigman M. Cognitive and verbal abilities of 24- to 36-month-old siblings of children with autism. J Autism Dev Disord. 2007;37(2):218–229. [PubMed] 38. Volkmar F, Chawarska K, Klin A. Autism in infancy and early childhood. Annu Rev Psychol. 2005;56:315–336. [PubMed] 39. Sumi S, Taniai H, Miyachi T, Tanemura M. Sibling risk of pervasive developmental disorder estimated by means of an epidemiologic survey in Nagoya, Japan. J Hum Genet. 2006;51(6):518–522. [PubMed] 40. Bailey A, Phillips W, Rutter M. Autism: towards an integration of clinical, genetic, neuropsychological, and neurobiological perspectives. J Child Psychol Psychiatry. 1996;37(1):89–126. [PubMed] 41. Ritvo ER, Freeman BJ, Pingree C, et al. The UCLA-University of Utah epidemiologic survey of autism: prevalence. Am J Psychiatry. 1989;146(2):194–199. [PubMed] 42. Wetherby AM, Watt N, Morgan L, Shumway S. Social communication profiles of children with autism spectrum disorders late in the second year of life. J Autism Dev Disord. 2007;37(5):960–975. [PubMed] 43. Wetherby AM, Woods J, Allen L, Cleary J, Dickinson H, Lord C. Early indicators of autism spectrum disorders in the second year of life. J Autism Dev Disord. 2004;34(5):473–493. [PubMed] 44. Bryson SE, Zwaigenbaum L, Brian J, et al. A prospective case series of high-risk infants who developed autism. J Autism Dev Disord. 2007;37(1):12–24. [PubMed] 45. Zwaigenbaum L, Bryson S, Rogers T, Roberts W, Brian J, Szatmari P. Behavioral manifestations of autism in the first year of life. Int J Dev Neurosci. 2005;23(2–3):143–152. [PubMed] 46. Ozonoff S, Macari S, Young GS, Goldring S, Thompson M, Rogers SJ. Atypical object exploration at 12 months of age is associated with autism in a prospective sample. Autism. 2008;12(5):457–472. [PMC free article] [PubMed] 47. Iverson JM, Wozniak RH. Variation in vocal-motor development in infant siblings of children with autism. J Autism Dev Disord. 2007;37(1):158–170. [PMC free article] [PubMed] 48. Landa R, Garrett-Mayer E. Development in infants with autism spectrum disorders: a prospective study. J Child Psychol Psychiatry. 2006;47(6):629–638. [PubMed] 49. Loh A, Soman T, Brian J, et al. Stereotyped motor behaviors associated with autism in high-risk infants: a pilot videotape analysis of a sibling sample. J Autism Dev Disord. 2007;37(1):25–36. [PubMed] 50. Landa RJ, Holman KC, Garrett-Mayer E. Social and communication development in toddlers with early and later diagnosis of autism spectrum disorders. Arch Gen Psychiatry. 2007;64(7):853–864. [PubMed] 51. Sullivan M, Finelli J, Marvin A, Garrett-Mayer E, Bauman M, Landa R. Response to joint attention in toddlers at risk for autism spectrum disorder: a prospective study. J Autism Dev Disord. 2007;37(1):37–48. [PubMed] 52. Mitchell S, Brian J, Zwaigenbaum L, et al. Early language and communication development of infants later diagnosed with autism spectrum disorder. J Dev Behav Pediatr. 2006;27(2 suppl):S69–S78. [PubMed] 53. Gamliel I, Yirmiya N, Sigman M. The development of young siblings of children with autism from 4 to 54 months. J Autism Dev Disord. 2007;37(1):171–183. [PubMed] 54. Dawson G, Osterling J, Meltzoff AN, Kuhl P. Case study of the development of an infant with autism from birth to two years of age. J Appl Dev Psychol. 2000;21(3):299–313. [PMC free article] [PubMed] 55. Baron-Cohen S, Allen J, Gillberg C. Can autism be detected at 18 months? The needle, the haystack, and the CHAT. Br J Psychiatry. 1992;161:839–843. [PubMed] 56. Baron-Cohen S, Cox A, Baird G, et al. Psychological markers in the detection of autism in infancy in a large population. Br J Psychiatry. 1996;168(2):158–163. [PubMed] 57. Baird G, Charman T, Baron-Cohen S, et al. A screening instrument for autism at 18 months of age: a 6-year follow-up study. J Am Acad Child Adolesc Psychiatry. 2000;39(6):694–702. [PubMed] 58. Robins DL, Fein D, Barton ML, Green JA. The Modified Checklist for Autism in Toddlers: an initial study investigating the early detection of autism and pervasive developmental disorders. J Autism Dev Disord. 2001;31(2):131–144. [PubMed] 59. Kleinman JM, Robins DL, Ventola PE, et al. The Modified Checklist for Autism in Toddlers: a follow-up study investigating the early detection of autism spectrum disorders. J Autism Dev Disord. 2008;38(5):827–839. [PMC free article] [PubMed] 60. Pandey J, Verbalis A, Robins D, et al. Screening for autism in older and younger toddlers with the Modified Checklist for Autism in Toddlers. Autism. 2008;12(5):513–535. [PubMed]
61. Wetherby A, Prizant B. Communication and Symbolic Behavior Scales: Developmental Profile. Baltimore, ME: Paul H. Brookes Publishing Company; 2002.
62. Wetherby A, Brosnan-Maddox S, Peace V, Newton L. Validation of the Infant-Toddler Checklist as a broadband screener for autism spectrum disorders from 9 to 24 months of age. Autism. 2008;12(5):487–511. [PMC free article] [PubMed] 63. Stone WL, McMahon CR, Henderson LM. Use of the Screening Tool for Autism in Two-Year-Olds (STAT) for children under 24 months: an exploratory study. Autism. 2008;12(5):557–573. [PubMed] 64. Bryson SE, Zwaigenbaum L, McDermott C, Rombough V, Brian J. The Autism Observation Scale for Infants: scale development and reliability data. J Autism Dev Disord. 2008;38(4):731–738. [PubMed] 65. Zwaigenbaum L. The Screening Tool for Autism in Two Year Olds can identify children at risk of autism. Evid Based Ment Health. 2005;8(3):69. [PubMed] 66. Watson LR, Baranek GT, Crais ER, Steven RJ, Dykstra J, Perryman T. The first year inventory: retrospective parent responses to a questionnaire designed to identify one-year-olds at risk for autism. J Autism Dev Disord. 2007;37(1):49–61. [PubMed] 67. Reznick JS, Baranek GT, Reavis S, Watson LR, Crais ER. A parent-report instrument for identifying one-year-olds at risk for an eventual diagnosis of autism: the first year inventory. J Autism Dev Disord. 2007;37(9):1691–1710. [PubMed] 68. Dosreis S, Weiner CL, Johnson L, Newschaffer CJ. Autism spectrum disorder screening and management practices among general pediatric providers. J Dev Behav Pediatr. 2006;27(2 suppl):S88–S94. [PubMed] 69. Pinto-Martin JA, Souders MC, Giarelli E, Levy SE. The role of nurses in screening for autistic spectrum disorder in pediatric primary care. J Pediatr Nurs. 2005;20(3):163–169. [PubMed] 70. Lannon CM, Flower K, Duncan P, Moore KS, Stuart J, Bassewitz J. The Bright Futures Training Intervention Project: implementing systems to support preventive and developmental services in practice. Pediatrics. 2008. Available at: www.pediatrics.org/cgi/content/full/122/1/e163. [PubMed] 71. Kennedy T, Regehr G, Rosenfield J, Roberts SW, Lingard L. Exploring the gap between knowledge and behavior: a qualitative study of clinician action following an educational intervention. Acad Med. 2004;79(5):386–393. [PubMed] 72. Howlin P, Asgharian A. The diagnosis of autism and Asperger syndrome: findings from a survey of 770 families. Dev Med Child Neurol. 1999;41(12):834–839. [PubMed] 73. Zwaigenbaum L. Autistic spectrum disorders in preschool children. Can Fam Physician. 2001;47:2037–2042. [PMC free article] [PubMed]
74. Lord C, Risi S. Autism spectrum disorder: a transactional developmental perspective. In: Wetherby AM, Prizant BM, editors. Diagnosis of Autism Spectrum Disorders in Young Children. London, United Kingdom: Paul H. Brookes Publishing Company; 2000. pp. 11–30.
75. Rutter M. Novartis Found Symp. Vol. 251. 2003. Introduction: autism—the challenges ahead; pp. 1–9. discussion 109–111, 281–297. [PubMed] 76. Stone WL, Hoffman EL, Lewis SE, Ousley OY. Early recognition of autism: parental reports vs clinical observation. Arch Pediatr Adolesc Med. 1994;148(2):174–179. [PubMed] 77. Chawarska K, Paul R, Klin A, Hannigen S, Dichtel LE, Volkmar F. Parental recognition of developmental problems in toddlers with autism spectrum disorders. J Autism Dev Disord. 2007;37(1):62–72. [PubMed] 78. Lord C, Risi S, Lambrecht L, et al. The Autism Diagnostic Observation Schedule-Generic: a standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord. 2000;30(3):205–223. [PubMed] 79. Risi S, Lord C, Gotham K, et al. Combining information from multiple sources in the diagnosis of autism spectrum disorders. J Am Acad Child Adolesc Psychiatry. 2006;45(9):1094–1103. [PubMed] 80. Chawarska K, Klin A, Paul R, Volkmar F. Autism spectrum disorder in the second year: stability and change in syndrome expression. J Child Psychol Psychiatry. 2007;48(2):128–138. [PubMed] 81. Gotham K, Risi S, Pickles A, Lord C. The Autism Diagnostic Observation Schedule: revised algorithms for improved diagnostic validity. J Autism Dev Disord. 2007;37(4):613–627. [PubMed]
82. Bayley N. Bayley Scales of Infant and Toddler Development. 3. San Antonio, TX: Harcourt Assessment, Inc; 2006.
83. Mullen E. Mullen Scales of Early Learning. Circle Pines, MN: American Guidance Service, Inc; 1995.
84. Striano T, Rochat P. Developmental link between dyadic and triadic social competence in infancy. Br J Dev Psychol. 1999;17(4):551–562.
85. Sparrow SS, Cicchetti DV, Balla DA. Vineland Adaptive Behaviour Scales. 2. Circle Pines, MN: American Guidance Service Inc; 1984.
86. Carter AS, Volkmar FR, Sparrow SS, et al. The Vineland Adaptive Behavior Scales: supplementary norms for individuals with autism. J Autism Dev Disord. 1998;28(4):287–302. [PubMed] 87. Stone WL, Ousley OY, Hepburn SL, Hogan KL, Brown CS. Patterns of adaptive behavior in very young children with autism. Am J Ment Retard. 1999;104(2):187–199. [PubMed] 88. Klin A, Saulnier CA, Sparrow SS, Cicchetti DV, Volkmar FR, Lord C. Social and communication abilities and disabilities in higher functioning individuals with autism spectrum disorders: the Vineland and the ADOS. J Autism Dev Disord. 2007;37(4):748–759. [PubMed] 89. Saulnier CA, Klin A. Brief report: social and communication abilities and disabilities in higher functioning individuals with autism and Asperger syndrome. J Autism Dev Disord. 2007;37(4):788–793. [PubMed]
90. Zimmerman I, Steiner V, Pond R. Preschool Language Scale. 4. San Antonio, TX: Harcourt; 2002.
91. Fenson L, Bates E, Dale P, Goodman J, Reznick JS, Thal D. Measuring variability in early child language: don’t shoot the messenger. Child Dev. 2000;71(2):323–328. [PubMed] 92. Caronna EB, Augustyn M, Zuckerman B. Revisiting parental concerns in the age of autism spectrum disorders: the need to help parents in the face of uncertainty. Arch Pediatr Adolesc Med. 2007;161(4):406–408. [PubMed] 93. Glascoe FP. Screening for developmental and behavioral problems. Ment Retard Dev Disabil Res Rev. 2005;11(3):173–179. [PubMed] 94. Merin N, Young GS, Ozonoff S, Rogers SJ. Visual fixation patterns during reciprocal social interaction distinguish a subgroup of 6-month-old infants at-risk for autism from comparison infants. J Autism Dev Disord. 2007;37(1):108–121. [PubMed] 95. Stone WL, McMahon CR, Yoder PJ, Walden TA. Early social-communicative and cognitive development of younger siblings of children with autism spectrum disorders. Arch Pediatr Adolesc Med. 2007;161(4):384–390. [PubMed] 96. Cassel TD, Messinger DS, Ibanez LV, Haltigan JD, Acosta SI, Buchman AC. Early social and emotional communication in the infant siblings of children with autism spectrum disorders: an examination of the broad phenotype. J Autism Dev Disord. 2007;37(1):122–132. [PubMed] 97. Presmanes AG, Walden TA, Stone WL, Yoder PJ. Effects of different attentional cues on responding to joint attention in younger siblings of children with autism spectrum disorders. J Autism Dev Disord. 2007;37(1):133–144. [PubMed]
98. Yirmiya N, Ozonoff S. The very early phenotype of autism. J Autism. 2007;37(1):1–11.
99. Lord C, Rutter M, Le CA. Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for care-givers of individuals with possible pervasive developmental disorders. J Autism Dev Disord. 1994;24(5):659–685. [PubMed] 100. Kleinman JM, Ventola PE, Pandey J, et al. Diagnostic stability in very young children with autism spectrum disorders. J Autism Dev Disord. 2008;38(4):606–615. [PMC free article] [PubMed]
101. Lord C, Bailey A. Autism spectrum disorders. In: Rutter M, Taylor ER, editors. Child and Adolescent Psychiatry. 4. New York, NY: Guilford Press; 2002. pp. 636–663.
102. Shattuck PT. The contribution of diagnostic substitution to the growing administrative prevalence of autism in US special education. Pediatrics. 2006;117(4):1028–1037. [PubMed] 103. Rogers SJ. Empirically supported comprehensive treatments for young children with autism. J Clin Child Psychol. 1998;27(2):168–179. [PubMed] 104. Landry SH, Smith KE, Swank PR, Assel MA, Vellet S. Does early responsive parenting have a special importance for children’s development or is consistency across early childhood necessary? Dev Psychol. 2001;37(3):387–403. [PubMed] 105. Masur EF, Flynn V, Eichorst DL. Maternal responsive and directive behaviours and utterances as predictors of children’s lexical development. J Child Lang. 2005;32(1):63–91. [PubMed]
106. Barr R, Hayne H. Age-related changes in imitation: implications for memory development. In: Lipsitt LP, Hayne H, editors. Progress in Infancy Research. Mahwah, NJ: Erlbaum; 2000. pp. 21–67.
107. National Association for the Education of Young Children. Developmentally appropriate practice in early childhood programs serving children from birth through age 8: a position statement of the National Association for the Education of Young Children. [Accessed January 9, 2009]. Available at: www.naeyc.org/about/positions/dap3.asp. 108. Green G, Brennan LC, Fein D. Intensive behavioral treatment for a toddler at high risk for autism. Behav Modif. 2002;26(1):69–102. [PubMed]
109. McGee GG, Morrier MJ, Daly T. An incidental teaching approach to early intervention for toddlers with autism. J Assoc Pers Sev Handicaps. 1999;24(3):133–146.
110. Wetherby A, Woods J. Early social interaction project for children with autism spectrum disorders beginning in the second year of life: a preliminary study. Top Early Child Spec Educ. 2006;26(2):67–82.
111. Smith CM, Rogers SJ, Dawson G. The Early Start Denver Model: a comprehensive early intervention approach for toddlers with autism. In: Handleman JS, Harris SL, editors. Preschool Education Programs for Children With Autism. 3. Austin, TX: Pro-Ed; 2006. pp. 65–101.
112. Mahoney G, Perales F, Wiggers B, Herman B. Responsive teaching: early intervention for children with Down syndrome and other disabilities. Downs Syndr Res Pract. 2006;11(1):18–28. [PubMed]
113. Sussman F. More Than Words: Helping Parents Promote Communication and Social Skills in Children With Autism Spectrum Disorder. Toronto, Ontario, Canada: The Hanen Centre; 1999.
114. Landa RJ. Diagnosis of autism spectrum disorders in the first 3 years of life. Nat Clin Pract Neurol. 2008;4(3):138–147. [PubMed]
115. Prizant BM, Wetherby AM, Rubin E, Laurent AC, Rydell PJ. The SCERTS Model: A Comprehensive Educational Approach for Children With Autism Spectrum Disorders. Baltimore, MD: Paul H. Brookes Publishing Company; 2006.