POC strategy for nA/H1N1v requires minimal training, necessitates a small dedicated laboratory area available in any hospital setting and can be operated by one person. It enables the hospital to provide diagnosis within the period of clinical illness. This is imperative if one wishes to take the decision to treat the patient, to decide to isolate the patient to prevent nosocomial transmission, or to discharge the patient. It provides reliable data for studies of the local epidemiology and its evolution. It also contributes to defining and monitoring the epidemiology on a larger scale (regional, national, international), via extrapolation based on the percentage of laboratory-confirmed cases compared with suspect cases. The usefulness of the POC strategy in the context of the nA/H1N1v pandemic demonstrates that POC could usefully be implemented throughout the country not only for emergency situations but also as a daily tool to improve the quality of care for hospitalized patients, by shortening the delays and allowing decisions during the period of clinical presentation. It is likely that hospitalization costs would also directly benefit from POC strategy, through reduction of the duration of hospitalization as previously demonstrated 
. Our experience demonstrates that POC laboratory implementation reduces the time necessary to obtain the results in all cases, even when the molecular techniques are not performed at the POC level. Although, the sensitivity of POC tests is usually lower than that of rtRT-PCR techniques, their high PPV enables clinical decisions to be taken much more rapidly than in the standard diagnostic approach.
One can argue that an efficient transportation system may be less expensive than setting up a POC facility because of the short distance (less than 10 km) between the North Hospital and the core laboratory. However, our experience is that delays due to transfer for medical ward to core laboratory can vary greatly (up to 7 hours). In our hospital system, samples transportation is operated by messengers (with cars). The long delays may be sometimes due to heavy traffic between the two hospitals (more than 1 hour). Beside, as MDs, we have no hierarchical authority on the messengers. This situation has been discussed with the administrative head of the hospital, but no satisfactory solution could be found. This is the reason why the POC laboratory solution has been considered and developed.
In our opinion, the decision to abandon systematic laboratory testing of suspect patients was equivalent to breaking the thermometer while attempting to define the body temperature curve. We believe that the application of diagnostic tools for respiratory tract infections (RTI) enables the doctors and nurses to work efficiently to combat this group of diseases that the most common cause of death worldwide 
and the most neglected cause of reduced longevity 
. In the current pandemic situation where less than 10% of tested specimens were found positive for nA/H1N1v, the economic impact of rapid testing through the POC strategy is very important. Indeed, all negative patients - the large majority of suspect patients for the considered study period - can therefore return to their professional activities immediately. The re-admission of students in the educational course is often conditioned by a certificate assessing the absence of contagiousness for nA/H1N1v, which needs to be based on specific virologic diagnostic tests such as those implemented in the POC strategy. Finally, a better knowledge of the local and seasonal ecology of RTI microorganisms must help to determine the panel of agents to be tested at the POC level. As an example, the findings that 34% of suspected nA/H1N1v infections were in fact due to rhinoviruses 
should theoretically justify POC testing for these viruses. It is also likely that the panel of POC detected pathogens will progressively increase to other agents causing respiratory tract infections. To address influenza morbidity and mortality, the approach based on systematic screening is more efficient than passive methods that produce underestimated data, in part due to the fact that they cannot consider the role of unrecognized influenza infection as a decisive co-morbidity factor in patients with underlying cardiovascular disease, hypertension, chronic pulmonary diseases and endocrine disorders 
. Therefore passive surveillance tends to hinder the knowledge of epidemiology of this pandemic 
. Systematic detection for each patient with severe influenza-associated pathology like acute respiratory distress syndrome 
or for each patient with high mortality risk like pregnant woman 
may contribute to appreciating the true incidence of influenza infection in such specific groups.