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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
Transl Res. Author manuscript; available in PMC 2011 January 1.
Published in final edited form as:
Transl Res. 2010 January; 155(1): 44.
doi: 10.1016/j.trsl.2009.09.002

Figure 1

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Effects of iloprost on BAL cell count and protein content in the two-hit VILI model

Mice were subjected to mechanical ventilation at high tidal volume (HTV, 30 ml/kg, 4 hr) with or without TRAP6 injection (3×10−7 mol/mouse i/t), or left spontaneously ventilated. Animals were treated with iloprost (2 μg/kg, i/v) or sterile saline at three time points (0, 40, and 80 min) during mechanical ventilation. Cell count (A) and measurements of protein concentration (B) were performed in BAL fluid taken from control and experimental animals; n=6–10 per condition; *p<0.03, **p<0.005.

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