Syringoma is a benign adnexal tumor that derives from the intraepidermal portion of the eccrine sweat ducts. Syringomas first appear during puberty or the third or fourth decade.[
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4,
5] Although the variety localized on the eyelid in middle-aged women is the most frequent, many other clinical variants are reported. Friedman and Butler proposed a classification, based on the clinical features and associations. This consisted of four principal clinical variants of syringoma: a localized form, a familial form, a form associated with Down's syndrome, and a generalized form that encompasses multiple and eruptive syringoma.[
1] The eruptions are generally asymptomatic, although pruritus has been reported in some cases. The lesions are benign and may spontaneously resolve, or, more commonly, remain stable.[
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Our case was a 28-year old woman who had lesions of generalized eruptive form. The patient presented with an eight-year history of a dermatosis. The lesions appeared on the forearm first, which was followed by successive eruptions on the face, chest, upper abdomen, thigh and neck respectively. The patient had mild pruritus during perspiration. There was no spontaneous resolution in the period of observation.
Treatment of syringoma is cosmetic. Therefore, it should not be confused with the above referred differential diagnosis. Options are abundant and generally unsatisfactory, as they are located in the dermis and often numerous. Physical techniques such as excision, electrocoagulation and liquid nitrogen cryotherapy and dermabrasion yield poor cosmetic results.[
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7,
8] Oral isotretinoin and topical tretinoin and adapalene have been used, as well as ablative techniques such as the CO
2 laser, with variable success; however, none eliminates the risk of recurrence and, therefore, treatment of syringoma is often frustrating.[
9] Most of the literature suggests using carbon dioxide laser.[
10–
12] One study demonstrates good results with temporary tattooing, following Q-switched alexandrite laser.[
13] Unfortunately, all surgical interventions result in scarring.[
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Treatment of syringoma is cosmetic. They are abundant and generally unsatisfactory. Treatment modalities have included dermabrasion, various methods of excision, cryosurgery, electrodesiccation, chemical peeling, and oral and topical retinoids.[
8–
10] Successful treatment of facial syringomas with carbon dioxide laser also has been reported.[
11] A recent report suggests the use of topical atropine to alleviate the pruritus in symptomatic eruptive syringoma.[
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