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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
Mol Pharm. Author manuscript; available in PMC 2010 December 7.
Published in final edited form as:
Mol Pharm. 2009 December 7; 6(6): 1848–1855.
doi: 10.1021/mp900150g

Figure 4

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Effect of HSA concentration on transfection efficiency of liposome-ODN complexes in KB cells. Bcl-2 mRNA expression determined by real-time RT-PCR (A), Bcl-2 protein expression determined by Western blot (B) and quantification of Bcl-2 protein level normalized by β-actin (C). 1) untreated cells; 2) Oligofectamine-ODN complexes; 3) liposome-ODN complexes coated with HSA at 0.15:100 molar ratio; 4) 1.5:100 molar ratio; 5) 3:100 molar ratio; 6) 4.5:100 molar ratio; 7) uncoated liposome-ODN complexes; 8) liposome-ODN complexes coated with HSA at 9:100 molar ratio; 9) liposome-ODN complexes co-incubation with excess HSA (150:100 molar ratio); 10) free G3139; 11) free G3622. Each value represents the mean ± SD of three repeat studies.

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