Search tips
Search criteria 


Logo of plosbiolPLoS BiologySubmit to PLoSGet E-mail AlertsContact UsPublic Library of Science (PLoS)View this Article
Published online 2009 October 20. doi: 10.1371/journal.pbio.1000218

Figure 4

An external file that holds a picture, illustration, etc.
Object name is pbio.1000218.g004.jpg
Yeast two-hybrid hits contain high-scoring PWM matches.

The phage-derived PWM for each SH3 domain was used to search the yeast proteome for matching peptides based on a PWM scoring algorithm, which ranks each peptide based on how closely it resembles the PWM. The fraction of yeast two-hybrid (Y2H) hits containing sequences with a rank score higher than the value on the x-axis is shown for: yeast two-hybrid interactions observed at least six times (solid line), yeast two-hybrid interactions observed at least one time (dashed line), and randomly chosen interactions (dotted line).

Images in this article

  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5
  • Figure 6
  • Figure 7
  • Figure 8
Click on the image to see a larger version.